skip to main content
Idioma:
Resultados 1 2 3 4 5 next page
Mostrar Somente
Result Number Material Type Add to My Shelf Action Record Details and Options
1
Fragment Screening Purely with Protein Crystallography
Fragment Screening Purely with Protein Crystallography
Material Type:
Artigo 		Adicionar ao Meu Espaço

Fragment Screening Purely with Protein Crystallography

Spurlino, John C.

Methods in Enzymology, 2011, Vol.493, p.321-356 [Periódico revisado por pares]

United States: Elsevier Science & Technology

Texto completo disponível

Citações Citado por
2
Discovery of Potent and Orally Bioavailable Pyridine N‑Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions
Discovery of Potent and Orally Bioavailable Pyridine N‑Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions
Material Type:
Artigo 		Adicionar ao Meu Espaço

Discovery of Potent and Orally Bioavailable Pyridine N‑Oxide-Based Factor XIa Inhibitors through Exploiting Nonclassical Interactions

Xu, Guozhang ; Liu, Zhijie ; Wang, Xinkang ; Lu, Tianbao ; DesJarlais, Renee L. ; Thieu, Tho ; Zhang, Jing ; Devine, Zheng Huang ; Du, Fuyong ; Li, Qiu ; Milligan, Cynthia M. ; Shaffer, Paul ; Cedervall, Peder E. ; Spurlino, John C. ; Stratton, Christopher F. ; Pietrak, Beth ; Szewczuk, Lawrence M. ; Wong, Victoria ; Steele, Ruth A. ; Bruinzeel, Wouter ; Chintala, Madhu ; Silva, Jose ; Gaul, Michael D. ; Macielag, Mark J. ; Nargund, Ravi

Journal of medicinal chemistry, 2022-08, Vol.65 (15), p.10419-10440 [Periódico revisado por pares]

American Chemical Society

Texto completo disponível

Citações Citado por
3
Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor
Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor
Material Type:
Artigo 		Adicionar ao Meu Espaço

Hit-to-lead optimization and discovery of a potent, and orally bioavailable G protein coupled receptor kinase 2 (GRK2) inhibitor

Xu, Guozhang ; Gaul, Michael D. ; Liu, Zhijie ; DesJarlais, Renee L. ; Qi, Jenson ; Wang, Weixue ; Krosky, Daniel ; Petrounia, Ioanna ; Milligan, Cynthia M. ; Hermans, An ; Lu, Hua-Rong ; Huang, Devine Zheng ; Xu, June Zhi ; Spurlino, John C.

Bioorganic & medicinal chemistry letters, 2020-12, Vol.30 (23), p.127602-127602, Article 127602 [Periódico revisado por pares]

England: Elsevier Ltd

Texto completo disponível

Citações Citado por
4
Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells
Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells
Material Type:
Artigo 		Adicionar ao Meu Espaço

Discovery and Cocrystal Structure of Benzodiazepinedione HDM2 Antagonists That Activate p53 in Cells

Grasberger, Bruce L ; Lu, Tianbao ; Schubert, Carsten ; Parks, Daniel J ; Carver, Theodore E ; Koblish, Holly K ; Cummings, Maxwell D ; LaFrance, Louis V ; Milkiewicz, Karen L ; Calvo, Raul R ; Maguire, Diane ; Lattanze, Jennifer ; Franks, Carol F ; Zhao, Shuyuan ; Ramachandren, Kannan ; Bylebyl, Gwendolyn R ; Zhang, Marie ; Manthey, Carl L ; Petrella, Eugene C ; Pantoliano, Michael W ; Deckman, Ingrid C ; Spurlino, John C ; Maroney, Anna C ; Tomczuk, Bruce E ; Molloy, Christopher J ; Bone, Roger F

Journal of medicinal chemistry, 2005-02, Vol.48 (4), p.909-912 [Periódico revisado por pares]

Washington, DC: American Chemical Society

Texto completo disponível

Citações Citado por
5
Extensive features of tight oligosaccharide binding revealed in high-resolution structures of the maltodextrin transport/chemosensory receptor
Extensive features of tight oligosaccharide binding revealed in high-resolution structures of the maltodextrin transport/chemosensory receptor
Material Type:
Artigo 		Adicionar ao Meu Espaço

Extensive features of tight oligosaccharide binding revealed in high-resolution structures of the maltodextrin transport/chemosensory receptor

Quiocho, Florante A ; Spurlino, John C ; Rodseth, Lynn E

Structure (London), 1997-08, Vol.5 (8), p.997-1015 [Periódico revisado por pares]

United States: Elsevier Inc

Texto completo disponível

Citações Citado por
6
Crystal Structure of the Tyrosine Kinase Domain of Colony-stimulating Factor-1 Receptor (cFMS) in Complex with Two Inhibitors
Crystal Structure of the Tyrosine Kinase Domain of Colony-stimulating Factor-1 Receptor (cFMS) in Complex with Two Inhibitors
Material Type:
Artigo 		Adicionar ao Meu Espaço

Crystal Structure of the Tyrosine Kinase Domain of Colony-stimulating Factor-1 Receptor (cFMS) in Complex with Two Inhibitors

Schubert, Carsten ; Schalk-Hihi, Céline ; Struble, Geoffrey T. ; Ma, Hong-Chang ; Petrounia, Ioanna P. ; Brandt, Benjamin ; Deckman, Ingrid C. ; Patch, Raymond J. ; Player, Mark R. ; Spurlino, John C. ; Springer, Barry A.

The Journal of biological chemistry, 2007-02, Vol.282 (6), p.4094-4101 [Periódico revisado por pares]

United States: Elsevier Inc

Texto completo disponível

Citações Citado por
7
Potency variation of small-molecule chymase inhibitors across species
Potency variation of small-molecule chymase inhibitors across species
Material Type:
Artigo 		Adicionar ao Meu Espaço

Potency variation of small-molecule chymase inhibitors across species

Kervinen, Jukka ; Crysler, Carl ; Bayoumy, Shariff ; Abad, Marta C. ; Spurlino, John ; Deckman, Ingrid ; Greco, Michael N. ; Maryanoff, Bruce E. ; de Garavilla, Lawrence

Biochemical pharmacology, 2010-10, Vol.80 (7), p.1033-1041 [Periódico revisado por pares]

Amsterdam: Elsevier Inc

Texto completo disponível

Citações Citado por
8
Crystallographic evidence of a large ligand-induced hinge-twist motion between the two domains of the maltodextrin binding protein involved in active transport and chemotaxis
Crystallographic evidence of a large ligand-induced hinge-twist motion between the two domains of the maltodextrin binding protein involved in active transport and chemotaxis
Material Type:
Artigo 		Adicionar ao Meu Espaço

Crystallographic evidence of a large ligand-induced hinge-twist motion between the two domains of the maltodextrin binding protein involved in active transport and chemotaxis

Sharff, Andrew J ; Rodseth, Lynn E ; Spurlino, John C ; Quiocho, Florante A

Biochemistry (Easton), 1992-11, Vol.31 (44), p.10657-10663 [Periódico revisado por pares]

Washington, DC: American Chemical Society

Texto completo disponível

Citações Citado por
9
Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives
Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives
Material Type:
Artigo 		Adicionar ao Meu Espaço

Potent, nonpeptide inhibitors of human mast cell tryptase. Synthesis and biological evaluation of novel spirocyclic piperidine amide derivatives

Costanzo, Michael J. ; Yabut, Stephen C. ; Zhang, Han-Cheng ; White, Kimberley B. ; de Garavilla, Lawrence ; Wang, Yuanping ; Minor, Lisa K. ; Tounge, Brett A. ; Barnakov, Alexander N. ; Lewandowski, Frank ; Milligan, Cynthia ; Spurlino, John C. ; Abraham, William M. ; Boswell-Smith, Victoria ; Page, Clive P. ; Maryanoff, Bruce E.

Bioorganic & medicinal chemistry, 2008-03, Vol.18 (6), p.2114-2121 [Periódico revisado por pares]

Oxford: Elsevier Ltd

Texto completo disponível

Citações Citado por
10
Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif
Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif
Material Type:
Artigo 		Adicionar ao Meu Espaço

Orally efficacious thrombin inhibitors with cyanofluorophenylacetamide as the P2 motif

Kreutter, Kevin D. ; Lu, Tianbao ; Lee, Lily ; Giardino, Edward C. ; Patel, Sharmila ; Huang, Hui ; Xu, Guozhang ; Fitzgerald, Mark ; Haertlein, Barbara J. ; Mohan, Venkatraman ; Crysler, Carl ; Eisennagel, Stephen ; Dasgupta, Malini ; McMillan, Martin ; Spurlino, John C. ; Huebert, Norman D. ; Maryanoff, Bruce E. ; Tomczuk, Bruce E. ; Damiano, Bruce P. ; Player, Mark R.

Bioorganic & medicinal chemistry, 2008-05, Vol.18 (9), p.2865-2870 [Periódico revisado por pares]

Oxford: Elsevier Ltd

Texto completo disponível

Citações Citado por
Resultados 1 2 3 4 5 next page

Personalize Seus Resultados

  1. Editar

Refine Search Results

Expandir Meus Resultados

  1.   

Mostrar Somente

  1. Recursos Online (49)
  2. Revistas revisadas por pares (49)

Refinar Meus Resultados

Tipo de Recurso 

  1. Artigos  (62)
  2. Dissertações  (1)
  3. Book Chapters  (1)
  4. Mais opções open sub menu

Data de Publicação 

De até
Refinar
  1. Antes de1994  (9)
  2. 1994Até2000  (13)
  3. 2001Até2005  (9)
  4. 2006Até2011  (19)
  5. Após 2011  (16)
  6. Mais opções open sub menu

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.