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RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents
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RG3487, a novel nicotinic α7 receptor partial agonist, improves cognition and sensorimotor gating in rodents

Wallace, Tanya L ; Callahan, Patrick M ; Tehim, Ashok ; Bertrand, Daniel ; Tombaugh, Geoffrey ; Wang, Shaojie ; Xie, Walter ; Rowe, Wayne B ; Ong, Voon ; Graham, Elizabeth ; Terry, Jr, Alvin V ; Rodefer, Joshua S ; Herbert, Brian ; Murray, Michael ; Porter, Richard ; Santarelli, Luca ; Lowe, David A

The Journal of pharmacology and experimental therapeutics, 2011-01, Vol.336 (1), p.242-253 [Periódico revisado por pares]

United States

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2
A Monoclonal Anti-Calcitonin Gene-Related Peptide Antibody Decreases Stress-Induced Colonic Hypersensitivity
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A Monoclonal Anti-Calcitonin Gene-Related Peptide Antibody Decreases Stress-Induced Colonic Hypersensitivity

Noor-Mohammadi, Ehsan ; Ligon, Casey Owen ; Mackenzie, Kimberly ; Stratton, Jennifer ; Shnider, Sara ; Greenwood-Van Meerveld, Beverley

The Journal of pharmacology and experimental therapeutics, 2021-12, Vol.379 (3), p.270-279 [Periódico revisado por pares]

United States

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3
Streptococcal Exotoxin Streptolysin O Causes Vascular Endothelial Dysfunction Through PKC β Activation
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Streptococcal Exotoxin Streptolysin O Causes Vascular Endothelial Dysfunction Through PKC β Activation

Mukohda, Masashi ; Nakamura, Sho ; Takeya, Kosuke ; Matsuda, Akira ; Yano, Takanori ; Seki, Mihiro ; Mizuno, Risuke ; Ozaki, Hiroshi

The Journal of pharmacology and experimental therapeutics, 2021-11, Vol.379 (2), p.117-124 [Periódico revisado por pares]

United States

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4
RTICBM-74 Is a Brain-Penetrant Cannabinoid Receptor Subtype 1 Allosteric Modulator that Reduces Alcohol Intake in Rats
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RTICBM-74 Is a Brain-Penetrant Cannabinoid Receptor Subtype 1 Allosteric Modulator that Reduces Alcohol Intake in Rats

Lovelock, Dennis F ; Nguyen, Thuy ; Van Voorhies, Kalynn ; Zhang, Yanan ; Besheer, Joyce

The Journal of pharmacology and experimental therapeutics, 2022-03, Vol.380 (3), p.153-161 [Periódico revisado por pares]

United States

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5
Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity
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Pharmacological profile of lurasidone, a novel antipsychotic agent with potent 5-hydroxytryptamine 7 (5-HT7) and 5-HT1A receptor activity

Ishibashi, Tadashi ; Horisawa, Tomoko ; Tokuda, Kumiko ; Ishiyama, Takeo ; Ogasa, Masaaki ; Tagashira, Rie ; Matsumoto, Kenji ; Nishikawa, Hiroyuki ; Ueda, Yoko ; Toma, Satoko ; Oki, Hitomi ; Tanno, Norihiko ; Saji, Ikutaro ; Ito, Akira ; Ohno, Yukihiro ; Nakamura, Mitsutaka

The Journal of pharmacology and experimental therapeutics, 2010-07, Vol.334 (1), p.171-181 [Periódico revisado por pares]

United States

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6
Antidepressant Potential of ( R )-Ketamine in Rodent Models: Comparison with ( S )-Ketamine
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Antidepressant Potential of ( R )-Ketamine in Rodent Models: Comparison with ( S )-Ketamine

Fukumoto, Kenichi ; Toki, Hidetoh ; Iijima, Michihiko ; Hashihayata, Takashi ; Yamaguchi, Jun-Ichi ; Hashimoto, Kenji ; Chaki, Shigeyuki

The Journal of pharmacology and experimental therapeutics, 2017-04, Vol.361 (1), p.9-16 [Periódico revisado por pares]

United States

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7
Development of CVN424: A Selective and Novel GPR6 Inverse Agonist Effective in Models of Parkinson Disease
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Development of CVN424: A Selective and Novel GPR6 Inverse Agonist Effective in Models of Parkinson Disease

Brice, Nicola L ; Schiffer, Hans H ; Monenschein, Holger ; Mulligan, Victoria J ; Page, Keith ; Powell, Justin ; Xu, Xiao ; Cheung, Toni ; Burley, J Russell ; Sun, Huikai ; Dickson, Louise ; Murphy, Sean T ; Kaushal, Nidhi ; Sheardown, Steve ; Lawrence, Jason ; Chen, Yun ; Bartkowski, Darian ; Kanta, Anne ; Russo, Joseph ; Hosea, Natalie ; Dawson, Lee A ; Hitchcock, Stephen H ; Carlton, Mark B

The Journal of pharmacology and experimental therapeutics, 2021-06, Vol.377 (3), p.407-416 [Periódico revisado por pares]

United States

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8
High Salt Upregulates Ca 2+ -Sensing Receptor Expression and Ca 2+ -Induced Relaxation of Contracted Mesenteric Arteries from Dahl Salt-Sensitive Rats
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High Salt Upregulates Ca 2+ -Sensing Receptor Expression and Ca 2+ -Induced Relaxation of Contracted Mesenteric Arteries from Dahl Salt-Sensitive Rats

Bridges, Lakeesha E ; Williams, Cicely L ; Awumey, Emmanuel M

The Journal of pharmacology and experimental therapeutics, 2022-05, Vol.381 (2), p.120-128 [Periódico revisado por pares]

United States

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9
FTBMT, a Novel and Selective GPR52 Agonist, Demonstrates Antipsychotic-Like and Procognitive Effects in Rodents, Revealing a Potential Therapeutic Agent for Schizophrenia
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FTBMT, a Novel and Selective GPR52 Agonist, Demonstrates Antipsychotic-Like and Procognitive Effects in Rodents, Revealing a Potential Therapeutic Agent for Schizophrenia

Nishiyama, Keiji ; Suzuki, Hirobumi ; Harasawa, Toshiya ; Suzuki, Noriko ; Kurimoto, Emi ; Kawai, Takayuki ; Maruyama, Minoru ; Komatsu, Hidetoshi ; Sakuma, Kensuke ; Shimizu, Yuji ; Shimojo, Masato

The Journal of pharmacology and experimental therapeutics, 2017-11, Vol.363 (2), p.253-264 [Periódico revisado por pares]

United States

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10
N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes
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N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a novel metabotropic glutamate 2 potentiator with potential anxiolytic/antidepressant properties: in vivo profiling suggests a link between behavioral and central nervous system neurochemical changes

Fell, Matthew J ; Witkin, Jeffrey M ; Falcone, Julie F ; Katner, Jason S ; Perry, Kenneth W ; Hart, John ; Rorick-Kehn, Linda ; Overshiner, Carl D ; Rasmussen, Kurt ; Chaney, Stephen F ; Benvenga, Mark J ; Li, Xia ; Marlow, Deanna L ; Thompson, Linda K ; Luecke, Susan K ; Wafford, Keith A ; Seidel, Wesley F ; Edgar, Dale M ; Quets, Anne T ; Felder, Christian C ; Wang, XuShan ; Heinz, Beverly A ; Nikolayev, Alexander ; Kuo, Ming-Shang ; Mayhugh, Daniel ; Khilevich, Albert ; Zhang, Deyi ; Ebert, Philip J ; Eckstein, James A ; Ackermann, Bradley L ; Swanson, Steven P ; Catlow, John T ; Dean, Robert A ; Jackson, Kimberley ; Tauscher-Wisniewski, Sitra ; Marek, Gerard J ; Schkeryantz, Jeffrey M ; Svensson, Kjell A

The Journal of pharmacology and experimental therapeutics, 2011-01, Vol.336 (1), p.165-177 [Periódico revisado por pares]

United States

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