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Material Type: Artigo
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Purinergic signaling during macrophage differentiation results in M2 alternative activated macrophagesBarberá‐Cremades, Maria ; Baroja‐Mazo, Alberto ; Pelegrín, PabloJournal of leukocyte biology, 2016-02, Vol.99 (2), p.289-299 [Periódico revisado por pares]United StatesTexto completo disponível |
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Material Type: Artigo
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Ibrutinib Plus Venetoclax for First-Line Treatment of Chronic Lymphocytic Leukemia: Primary Analysis Results From the Minimal Residual Disease Cohort of the Randomized Phase II CAPTIVATE StudyWierda, William G ; Allan, John N ; Siddiqi, Tanya ; Kipps, Thomas J ; Opat, Stephen ; Tedeschi, Alessandra ; Badoux, Xavier C ; Kuss, Bryone J ; Jackson, Sharon ; Moreno, Carol ; Jacobs, Ryan ; Pagel, John M ; Flinn, Ian ; Pak, Yvonne ; Zhou, Cathy ; Szafer-Glusman, Edith ; Ninomoto, Joi ; Dean, James P ; James, Danelle F ; Ghia, Paolo ; Tam, Constantine SJournal of clinical oncology, 2021-12, Vol.39 (34), p.3853-3865 [Periódico revisado por pares]United States: Wolters Kluwer HealthTexto completo disponível |
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Material Type: Artigo
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Long-Term Follow-Up of Ibrutinib Monotherapy in Symptomatic, Previously Treated Patients With Waldenström MacroglobulinemiaTreon, Steven P ; Meid, Kirsten ; Gustine, Joshua ; Yang, Guang ; Xu, Lian ; Liu, Xia ; Patterson, Christopher J ; Hunter, Zachary R ; Branagan, Andrew R ; Laubach, Jacob P ; Ghobrial, Irene M ; Palomba, M Lia ; Advani, Ranjana ; Castillo, Jorge JJournal of clinical oncology, 2021-02, Vol.39 (6), p.565-575 [Periódico revisado por pares]United States: American Society of Clinical OncologyTexto completo disponível |
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Material Type: Artigo
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Characterization of a Novel PERK Kinase Inhibitor with Antitumor and Antiangiogenic ActivityATKINS, Charity ; QI LIU ; CHOUDHRY, Anthony E ; ALSAID, Hasan ; JUCKER, Beat M ; AXTEN, Jeffrey M ; KUMAR, Rakesh ; MINTHORN, Elisabeth ; ZHANG, Shu-Yun ; FIGUEROA, David J ; MOSS, Katherine ; STANLEY, Thomas B ; SANDERS, Brent ; GOETZ, Aaron ; GAUL, NathanCancer research (Chicago, Ill.), 2013-03, Vol.73 (6), p.1993-2002 [Periódico revisado por pares]Philadelphia, PA: American Association for Cancer ResearchTexto completo disponível |
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Material Type: Artigo
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Prediction of Outcome in Patients With Chronic Lymphocytic Leukemia Treated With Ibrutinib: Development and Validation of a Four-Factor Prognostic ModelAhn, Inhye E ; Tian, Xin ; Ipe, David ; Cheng, Mei ; Albitar, Maher ; Tsao, L Claire ; Zhang, Lei ; Ma, Wanlong ; Herman, Sarah E M ; Gaglione, Erika M ; Soto, Susan ; Dean, James P ; Wiestner, AdrianJournal of clinical oncology, 2021-02, Vol.39 (6), p.576-585 [Periódico revisado por pares]United States: American Society of Clinical OncologyTexto completo disponível |
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Material Type: Artigo
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Acute metformin preconditioning confers neuroprotection against focal cerebral ischaemia by pre‐activation of AMPK‐dependent autophagyJiang, Teng ; Yu, Jin‐Tai ; Zhu, Xi‐Chen ; Wang, Hui‐Fu ; Tan, Meng‐Shan ; Cao, Lei ; Zhang, Qiao‐Quan ; Gao, Li ; Shi, Jian‐Quan ; Zhang, Ying‐Dong ; Tan, LanBritish journal of pharmacology, 2014-07, Vol.171 (13), p.3146-3157 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Mechanisms of Resistance to Noncovalent Bruton’s Tyrosine Kinase InhibitorsWang, Eric ; Mi, Xiaoli ; Thompson, Meghan C ; Montoya, Skye ; Notti, Ryan Q ; Afaghani, Jumana ; Durham, Benjamin H ; Penson, Alex ; Witkowski, Matthew T ; Lu, Sydney X ; Bourcier, Jessie ; Hogg, Simon J ; Erickson, Caroline ; Cui, Dan ; Cho, Hana ; Singer, Michael ; Totiger, Tulasigeri M ; Chaudhry, Sana ; Geyer, Mark ; Alencar, Alvaro ; Linley, Adam J ; Palomba, M. Lia ; Coombs, Catherine C ; Park, Jae H ; Zelenetz, Andrew ; Roeker, Lindsey ; Rosendahl, Mary ; Tsai, Donald E ; Ebata, Kevin ; Brandhuber, Barbara ; Hyman, David M ; Aifantis, Iannis ; Mato, Anthony ; Taylor, Justin ; Abdel-Wahab, OmarThe New England journal of medicine, 2022-02, Vol.386 (8), p.735-743 [Periódico revisado por pares]United States: Massachusetts Medical SocietyTexto completo disponível |
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8 |
Material Type: Artigo
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Pharmacological targeting of the pseudokinase Her3Xie, Ting ; Lim, Sang Min ; Westover, Kenneth D ; Dodge, Michael E ; Ercan, Dalia ; Ficarro, Scott B ; Udayakumar, Durga ; Gurbani, Deepak ; Tae, Hyun Seop ; Riddle, Steven M ; Sim, Taebo ; Marto, Jarrod A ; Jänne, Pasi A ; Crews, Craig M ; Gray, Nathanael SNature chemical biology, 2014-12, Vol.10 (12), p.1006-1012 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Cell-to-cell spread of HIV permits ongoing replication despite antiretroviral therapySIGAL, Alex ; KIM, Jocelyn T ; BALAZS, Alejandro B ; DEKEL, Erez ; MAYO, Avi ; MILO, Ron ; BALTIMORE, DavidNature (London), 2011-09, Vol.477 (7362), p.95-98 [Periódico revisado por pares]London: Nature Publishing GroupTexto completo disponível |
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10 |
Material Type: Artigo
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Therapeutic modulation of eIF2α phosphorylation rescues TDP-43 toxicity in amyotrophic lateral sclerosis disease modelsKim, Hyung-Jun ; Raphael, Alya R ; LaDow, Eva S ; McGurk, Leeanne ; Weber, Ross A ; Trojanowski, John Q ; Lee, Virginia M-Y ; Finkbeiner, Steven ; Gitler, Aaron D ; Bonini, Nancy MNature genetics, 2014-02, Vol.46 (2), p.152-160 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |