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1
Sestrin2 is a leucine sensor for the mTORC1 pathway
Sestrin2 is a leucine sensor for the mTORC1 pathway
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Sestrin2 is a leucine sensor for the mTORC1 pathway

Wolfson, Rachel L. ; Chantranupong, Lynne ; Saxton, Robert A. ; Shen, Kuang ; Scaria, Sonia M. ; Cantor, Jason R. ; Sabatini, David M.

Science (American Association for the Advancement of Science), 2016-01, Vol.351 (6268), p.43-48 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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2
Loss of leucine-rich repeat kinase 2 (LRRK2) in rats leads to progressive abnormal phenotypes in peripheral organs
Loss of leucine-rich repeat kinase 2 (LRRK2) in rats leads to progressive abnormal phenotypes in peripheral organs
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Loss of leucine-rich repeat kinase 2 (LRRK2) in rats leads to progressive abnormal phenotypes in peripheral organs

Baptista, Marco A S ; Dave, Kuldip D ; Frasier, Mark A ; Sherer, Todd B ; Greeley, Melanie ; Beck, Melissa J ; Varsho, Julie S ; Parker, George A ; Moore, Cindy ; Churchill, Madeline J ; Meshul, Charles K ; Fiske, Brian K Moore, Darren J

PloS one, 2013-11, Vol.8 (11), p.e80705-e80705 [Periódico revisado por pares]

United States: Public Library of Science

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3
Differential regulation of mTORC1 by leucine and glutamine
Differential regulation of mTORC1 by leucine and glutamine
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Differential regulation of mTORC1 by leucine and glutamine

Jewell, Jenna L. ; Kim, Young Chul ; Russell, Ryan C. ; Yu, Fa-Xing ; Park, Hyun Woo ; Plouffe, Steven W. ; Tagliabracci, Vincent S. ; Guan, Kun-Liang

Science (American Association for the Advancement of Science), 2015-01, Vol.347 (6218), p.194-198 [Periódico revisado por pares]

Washington: American Association for the Advancement of Science

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4
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway
Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway
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Structural basis for leucine sensing by the Sestrin2-mTORC1 pathway

Saxton, Robert A. ; Knockenhauer, Kevin E. ; Wolfson, Rachel L. ; Chantranupong, Lynne ; Pacold, Michael E. ; Wang, Tim ; Schwartz, Thomas U. ; Sabatini, David M.

Science (American Association for the Advancement of Science), 2016-01, Vol.351 (6268), p.53-58 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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5
Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine
Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine
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Zonated leucine sensing by Sestrin-mTORC1 in the liver controls the response to dietary leucine

Cangelosi, Andrew L ; Puszynska, Anna M ; Roberts, Justin M ; Armani, Andrea ; Nguyen, Thao P ; Spinelli, Jessica B ; Kunchok, Tenzin ; Wang, Brianna ; Chan, Sze Ham ; Lewis, Caroline A ; Comb, William C ; Bell, George W ; Helman, Aharon ; Sabatini, David M

Science (American Association for the Advancement of Science), 2022-07, Vol.377 (6601), p.47-56 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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6
Epoxymicheliolide, a novelguaiane-type sesquiterpene lactone, inhibits NF‑κB/COX‑2 signaling pathways by targeting leucine 281 and leucine 25 in IKKβ in renal cell carcinoma
Epoxymicheliolide, a novelguaiane-type sesquiterpene lactone, inhibits NF‑κB/COX‑2 signaling pathways by targeting leucine 281 and leucine 25 in IKKβ in renal cell carcinoma
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Epoxymicheliolide, a novelguaiane-type sesquiterpene lactone, inhibits NF‑κB/COX‑2 signaling pathways by targeting leucine 281 and leucine 25 in IKKβ in renal cell carcinoma

Zhu, Jiabin ; Zhao, Jun ; Yu, Zhenlong ; Shrestha, Sandeep ; Song, Jing ; Liu, Wenwen ; Lan, Wen ; Xing, Jinshan ; Liu, Shuang ; Chen, Chen ; Cao, Momo ; Sun, Xiuzhen ; Wang, Qi ; Song, Xishuang

International journal of oncology, 2018-06, Vol.53 (3), p.987-1000

Athens: Spandidos Publications UK Ltd

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7
A cold-adapted leucine dehydrogenase from marine bacterium Alcanivorax dieselolei: Characterization and l-tert-leucine production
A cold-adapted leucine dehydrogenase from marine bacterium Alcanivorax dieselolei: Characterization and l-tert-leucine production
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A cold-adapted leucine dehydrogenase from marine bacterium Alcanivorax dieselolei: Characterization and l-tert-leucine production

Jiang, Wei ; Sun, Dongfang ; Lu, Jixue ; Wang, Yali ; Wang, Shizhen ; Zhang, Yonghui ; Fang, Baishan

Engineering in life sciences, 2016-04, Vol.16 (3), p.283-289 [Periódico revisado por pares]

Blackwell Publishing Ltd

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8
Lysine and Leucine Deficiencies Affect Myocytes Development and IGF Signaling in Gilthead Sea Bream (Sparus aurata)
Lysine and Leucine Deficiencies Affect Myocytes Development and IGF Signaling in Gilthead Sea Bream (Sparus aurata)
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Lysine and Leucine Deficiencies Affect Myocytes Development and IGF Signaling in Gilthead Sea Bream (Sparus aurata)

Azizi, Sheida ; Nematollahi, Mohammad Ali ; Mojazi Amiri, Bagher ; Vélez, Emilio J ; Lutfi, Esmail ; Navarro, Isabel ; Capilla, Encarnación ; Gutiérrez, Joaquim Prunet, Patrick

PloS one, 2016-01, Vol.11 (1), p.e0147618-e0147618 [Periódico revisado por pares]

United States: Public Library of Science

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9
Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein
Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein
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Leucine-Rich Repeat Kinase 2 Regulates the Progression of Neuropathology Induced by Parkinson's-Disease-Related Mutant α-synuclein

Lin, Xian ; Parisiadou, Loukia ; Gu, Xing-Long ; Wang, Lizhen ; Shim, Hoon ; Sun, Lixin ; Xie, Chengsong ; Long, Cai-Xia ; Yang, Wan-Jou ; Ding, Jinhui ; Chen, Zsu Zsu ; Gallant, Paul E. ; Tao-Cheng, Jung-Hwa ; Rudow, Gay ; Troncoso, Juan C. ; Liu, Zhihua ; Li, Zheng ; Cai, Huaibin

Neuron (Cambridge, Mass.), 2009-12, Vol.64 (6), p.807-827 [Periódico revisado por pares]

United States: Elsevier Inc

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10
A metabolite of leucine (β-hydroxy-β-methylbutyrate) given to sows during pregnancy alters bone development of their newborn offspring by hormonal modulation
A metabolite of leucine (β-hydroxy-β-methylbutyrate) given to sows during pregnancy alters bone development of their newborn offspring by hormonal modulation
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A metabolite of leucine (β-hydroxy-β-methylbutyrate) given to sows during pregnancy alters bone development of their newborn offspring by hormonal modulation

Blicharski, Tomasz ; Tomaszewska, Ewa ; Dobrowolski, Piotr ; Hułas-Stasiak, Monika ; Muszyński, Siemowit Gonzalez-Bulnes, Antonio

PloS one, 2017-06, Vol.12 (6), p.e0179693-e0179693 [Periódico revisado por pares]

United States: Public Library of Science

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