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BRAF Inhibitor Resistance Mechanisms in Metastatic Melanoma: Spectrum and Clinical Impact
BRAF Inhibitor Resistance Mechanisms in Metastatic Melanoma: Spectrum and Clinical Impact
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BRAF Inhibitor Resistance Mechanisms in Metastatic Melanoma: Spectrum and Clinical Impact

RIZOS, Helen ; MENZIES, Alexander M ; HOWIE, Julie ; SAW, Robyn ; THOMPSON, John F ; KEFFORD, Richard F ; SCOLYER, Richard A ; LONG, Georgina V ; PUPO, Gulietta M ; CARLINO, Matteo S ; FUNG, Carina ; HYMAN, Jessica ; HAYDU, Lauren E ; MIJATOV, Branka ; BECKER, Therese M ; BOYD, Suzanah C

Clinical cancer research, 2014-04, Vol.20 (7), p.1965-1977 [Periódico revisado por pares]

Philadelphia, PA: American Association for Cancer Research

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2
Increased MAPK reactivation in early resistance to dabrafenib/trametinib combination therapy of BRAF-mutant metastatic melanoma
Increased MAPK reactivation in early resistance to dabrafenib/trametinib combination therapy of BRAF-mutant metastatic melanoma
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Increased MAPK reactivation in early resistance to dabrafenib/trametinib combination therapy of BRAF-mutant metastatic melanoma

Long, Georgina V ; Fung, Carina ; Menzies, Alexander M ; Pupo, Gulietta M ; Carlino, Matteo S ; Hyman, Jessica ; Shahheydari, Hamideh ; Tembe, Varsha ; Thompson, John F ; Saw, Robyn P ; Howle, Julie ; Hayward, Nicholas K ; Johansson, Peter ; Scolyer, Richard A ; Kefford, Richard F ; Rizos, Helen

Nature communications, 2014-12, Vol.5 (1), p.5694-5694, Article 5694 [Periódico revisado por pares]

England: Nature Publishing Group

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3
Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis
Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis
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Response of BRAF-mutant melanoma to BRAF inhibition is mediated by a network of transcriptional regulators of glycolysis

Parmenter, Tiffany J ; Kleinschmidt, Margarete ; Kinross, Kathryn M ; Bond, Simon T ; Li, Jason ; Kaadige, Mohan R ; Rao, Aparna ; Sheppard, Karen E ; Hugo, Willy ; Pupo, Gulietta M ; Pearson, Richard B ; McGee, Sean L ; Long, Georgina V ; Scolyer, Richard A ; Rizos, Helen ; Lo, Roger S ; Cullinane, Carleen ; Ayer, Donald E ; Ribas, Antoni ; Johnstone, Ricky W ; Hicks, Rodney J ; McArthur, Grant A

Cancer discovery, 2014-04, Vol.4 (4), p.423-433

United States

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4
Differential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanoma
Differential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanoma
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Differential activity of MEK and ERK inhibitors in BRAF inhibitor resistant melanoma

Carlino, Matteo S. ; Todd, Jason R. ; Gowrishankar, Kavitha ; Mijatov, Branka ; Pupo, Gulietta M. ; Fung, Carina ; Snoyman, Stephanie ; Hersey, Peter ; Long, Georgina V. ; Kefford, Richard F. ; Rizos, Helen

Molecular oncology, 2014-05, Vol.8 (3), p.544-554 [Periódico revisado por pares]

United States: Elsevier B.V

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5
The Epigenetic Regulator I-BET151 Induces BIM-Dependent Apoptosis and Cell Cycle Arrest of Human Melanoma Cells
The Epigenetic Regulator I-BET151 Induces BIM-Dependent Apoptosis and Cell Cycle Arrest of Human Melanoma Cells
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The Epigenetic Regulator I-BET151 Induces BIM-Dependent Apoptosis and Cell Cycle Arrest of Human Melanoma Cells

Gallagher, Stuart J. ; Mijatov, Branka ; Gunatilake, Dilini ; Tiffen, Jessamy C. ; Gowrishankar, Kavitha ; Jin, Lei ; Pupo, Gulietta M. ; Cullinane, Carleen ; Prinjha, Rab K. ; Smithers, Nicholas ; McArthur, Grant A. ; Rizos, Helen ; Hersey, Peter

Journal of investigative dermatology, 2014-11, Vol.134 (11), p.2795-2805 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes
Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes
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Targeting activating mutations of EZH2 leads to potent cell growth inhibition in human melanoma by derepression of tumor suppressor genes

Tiffen, Jessamy C ; Gunatilake, Dilini ; Gallagher, Stuart J ; Gowrishankar, Kavitha ; Heinemann, Anja ; Cullinane, Carleen ; Dutton-Regester, Ken ; Pupo, Gulietta M ; Strbenac, Dario ; Yang, Jean Y ; Madore, Jason ; Mann, Graham J ; Hayward, Nicholas K ; McArthur, Grant A ; Filipp, Fabian V ; Hersey, Peter

Oncotarget, 2015-09, Vol.6 (29), p.27023-27036

United States: Impact Journals LLC

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7
Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor
Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor
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Mutant B-RAF-Mcl-1 survival signaling depends on the STAT3 transcription factor

Becker, T M ; Boyd, S C ; Mijatov, B ; Gowrishankar, K ; Snoyman, S ; Pupo, G M ; Scolyer, R A ; Mann, G J ; Kefford, R F ; Zhang, X D ; Rizos, H

Oncogene, 2014-02, Vol.33 (9), p.1158-1166 [Periódico revisado por pares]

England: Nature Publishing Group

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8
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma
A high-throughput panel for identifying clinically relevant mutation profiles in melanoma
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A high-throughput panel for identifying clinically relevant mutation profiles in melanoma

Dutton-Regester, Ken ; Irwin, Darryl ; Hunt, Priscilla ; Aoude, Lauren G ; Tembe, Varsha ; Pupo, Gulietta M ; Lanagan, Cathy ; Carter, Candace D ; O'Connor, Linda ; O'Rourke, Michael ; Scolyer, Richard A ; Mann, Graham J ; Schmidt, Christopher W ; Herington, Adrian ; Hayward, Nicholas K

Molecular cancer therapeutics, 2012-04, Vol.11 (4), p.888-897 [Periódico revisado por pares]

United States

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9
Effect of a novel quaternary ammonium methacrylate polymer (QAMP) on adhesion and antibacterial properties of dental adhesives
Effect of a novel quaternary ammonium methacrylate polymer (QAMP) on adhesion and antibacterial properties of dental adhesives
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Effect of a novel quaternary ammonium methacrylate polymer (QAMP) on adhesion and antibacterial properties of dental adhesives

Pupo, Yasmine M ; Farago, Paulo Vitor ; Nadal, Jessica M ; Simão, Luzia C ; Esmerino, Luís Antônio ; Gomes, Osnara M M ; Gomes, João Carlos

International journal of molecular sciences, 2014-05, Vol.15 (5), p.8998-9015 [Periódico revisado por pares]

Switzerland: MDPI AG

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10
Evolutionary relationships among pathogenic and nonpathogenic Escherichia coli strains inferred from multilocus enzyme electrophoresis and mdh sequence studies
Evolutionary relationships among pathogenic and nonpathogenic Escherichia coli strains inferred from multilocus enzyme electrophoresis and mdh sequence studies
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Evolutionary relationships among pathogenic and nonpathogenic Escherichia coli strains inferred from multilocus enzyme electrophoresis and mdh sequence studies

PUPO, G. M ; KARAOLIS, D. K. R ; LAN, R ; REEVES, P. R

Infection and Immunity, 1997-07, Vol.65 (7), p.2685-2692 [Periódico revisado por pares]

Washington, DC: American Society for Microbiology

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