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Material Type: Artigo
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Improved glycemic control with minimal systemic metformin exposure: Effects of Metformin Delayed-Release (Metformin DR) targeting the lower bowel over 16 weeks in a randomized trial in subjects with type 2 diabetesHenry, Robert R ; Frias, Juan P ; Walsh, Brandon ; Skare, Sharon ; Hemming, John ; Burns, Colleen ; Bicsak, Thomas A ; Baron, Alain ; Fineman, Mark Samocha-Bonet, DoritPloS one, 2018-09, Vol.13 (9), p.e0203946-e0203946 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Efficacy and Safety of Dulaglutide 3.0 mg and 4.5 mg Versus Dulaglutide 1.5 mg in Metformin-Treated Patients With Type 2 Diabetes in a Randomized Controlled Trial (AWARD-11)Frias, Juan P ; Bonora, Enzo ; Nevarez Ruiz, Luis ; Li, Ying G ; Yu, Zhuoxin ; Milicevic, Zvonko ; Malik, Raleigh ; Bethel, M Angelyn ; Cox, David ADiabetes care, 2021-03, Vol.44 (3), p.765-773 [Periódico revisado por pares]United States: American Diabetes AssociationTexto completo disponível |
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Material Type: Artigo
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Effect of exenatide QW or placebo, both added to titrated insulin glargine, in uncontrolled type 2 diabetes: The DURATION‐7 randomized studyGuja, Cristian ; Frías, Juan P. ; Somogyi, Aniko ; Jabbour, Serge ; Wang, Hui ; Hardy, Elise ; Rosenstock, JulioDiabetes, obesity & metabolism, 2018-07, Vol.20 (7), p.1602-1614Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Tolerability, safety and pharmacodynamics of oral, small‐molecule glucagon‐like peptide‐1 receptor agonist danuglipron for type 2 diabetes: A 12‐week, randomized, placebo‐controlled, Phase 2 study comparing different dose‐escalation schemesSaxena, Aditi R. ; Frias, Juan P. ; Gorman, Donal N. ; Lopez, Rene N. ; Andrawis, Nabil ; Tsamandouras, Nikolaos ; Birnbaum, Morris J.Diabetes, obesity & metabolism, 2023-10, Vol.25 (10), p.2805-2814Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Effects of once-weekly semaglutide vs once-daily canagliflozin on body composition in type 2 diabetes: a substudy of the SUSTAIN 8 randomised controlled clinical trialMcCrimmon, Rory J. ; Catarig, Andrei-Mircea ; Frias, Juan P. ; Lausvig, Nanna L. ; le Roux, Carel W. ; Thielke, Desirée ; Lingvay, IldikoDiabetologia, 2020-03, Vol.63 (3), p.473-485 [Periódico revisado por pares]Berlin/Heidelberg: Springer Berlin HeidelbergTexto completo disponível |
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Material Type: Artigo
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Effect of dulaglutide 3.0 and 4.5 mg on weight in patients with type 2 diabetes: Exploratory analyses of AWARD‐11Bonora, Enzo ; Frias, Juan P. ; Tinahones, Francisco J. ; Van, Joanna ; Malik, Raleigh E. ; Yu, Zhuoxin ; Mody, Reema ; Bethel, Angelyn ; Kwan, Anita Y. M. ; Cox, David A.Diabetes, obesity & metabolism, 2021-10, Vol.23 (10), p.2242-2250Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Effects of exenatide once weekly plus dapagliflozin, exenatide once weekly, or dapagliflozin, added to metformin monotherapy, on body weight, systolic blood pressure, and triglycerides in patients with type 2 diabetes in the DURATION‐8 studyJabbour, Serge A. ; Frías, Juan P. ; Guja, Cristian ; Hardy, Elise ; Ahmed, Azazuddin ; Öhman, PeterDiabetes, obesity & metabolism, 2018-06, Vol.20 (6), p.1515-1519Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Efficacy and safety of an expanded dulaglutide dose range: A phase 2, placebo‐controlled trial in patients with type 2 diabetes using metforminFrias, Juan P. ; Wynne, Alan G. ; Matyjaszek‐Matuszek, Beata ; Bartaskova, Dagmar ; Cox, David A. ; Woodward, Brad ; Li, Ying G. ; Tham, Lai S. ; Milicevic, ZvonkoDiabetes, obesity & metabolism, 2019-09, Vol.21 (9), p.2048-2057Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Effects of exenatide once weekly plus dapagliflozin, exenatide once weekly alone, or dapagliflozin alone added to metformin monotherapy in subgroups of patients with type 2 diabetes in the DURATION‐8 randomized controlled trialFrías, Juan P. ; Hardy, Elise ; Ahmed, Azazuddin ; Öhman, Peter ; Jabbour, Serge ; Wang, Hui ; Guja, CristianDiabetes, obesity & metabolism, 2018-06, Vol.20 (6), p.1520-1525Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Long‐term effects of dapagliflozin plus saxagliptin versus glimepiride on a background of metformin in patients with type 2 diabetes: Results of a 104‐week extension to a 52‐week randomized, phase 3 study and liver fat MRI substudyFrías, Juan P. ; Maaske, Jill ; Suchower, Lisa ; Johansson, Lars ; Hockings, Paul D. ; Iqbal, Nayyar ; Wilding, John P. H.Diabetes, obesity & metabolism, 2022-01, Vol.24 (1), p.61-71Oxford, UK: Blackwell Publishing LtdTexto completo disponível |