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Refinado por: assunto: Chemistry, Medicinal remover
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1
Solid-phase synthesis of novel inhibitors of Farnesyl Transferase
Solid-phase synthesis of novel inhibitors of Farnesyl Transferase
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Solid-phase synthesis of novel inhibitors of Farnesyl Transferase

Barber, Amelia Moreno ; Hardcastle, Ian R ; Rowlands, Martin G ; Nutley, Bernard P ; Marriott, Jonathan H ; Jarman, Michael

Bioorganic & medicinal chemistry letters, 1999-02, Vol.9 (4), p.623-626 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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2
Inhibition of enzymes of estrogen and androgen biosynthesis by esters of 4-pyridylacetic acid
Inhibition of enzymes of estrogen and androgen biosynthesis by esters of 4-pyridylacetic acid
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Inhibition of enzymes of estrogen and androgen biosynthesis by esters of 4-pyridylacetic acid

McCague, Raymond ; Rowlands, Martin G ; Barrie, S. Elaine ; Houghton, John

Journal of medicinal chemistry, 1990-11, Vol.33 (11), p.3050-3055 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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3
Conformational analysis of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione (rogletimide) and discovery of potent 5-alkyl derivatives
Conformational analysis of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione (rogletimide) and discovery of potent 5-alkyl derivatives
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Conformational analysis of the aromatase inhibitor 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione (rogletimide) and discovery of potent 5-alkyl derivatives

McCague, Raymond ; Rowlands, Martin G

Journal of medicinal chemistry, 1992-10, Vol.35 (20), p.3699-3704 [Periódico revisado por pares]

WASHINGTON: American Chemical Society

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4
3- and 4-pyridylalkyl adamantanecarboxylates: inhibitors of human cytochrome P450(17 alpha) (17 alpha-hydroxylase/C17,20-lyase). Potential nonsteroidal agents for the treatment of prostatic cancer
3- and 4-pyridylalkyl adamantanecarboxylates: inhibitors of human cytochrome P450(17 alpha) (17 alpha-hydroxylase/C17,20-lyase). Potential nonsteroidal agents for the treatment of prostatic cancer
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3- and 4-pyridylalkyl adamantanecarboxylates: inhibitors of human cytochrome P450(17 alpha) (17 alpha-hydroxylase/C17,20-lyase). Potential nonsteroidal agents for the treatment of prostatic cancer

Chan, F C ; Potter, G A ; Barrie, S E ; Haynes, B P ; Rowlands, M G ; Houghton, J ; Jarman, M

Journal of medicinal chemistry, 1996-08, Vol.39 (17), p.3319-3323 [Periódico revisado por pares]

United States

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5
Analogs of aminoglutethimide: selective inhibition of aromatase
Analogs of aminoglutethimide: selective inhibition of aromatase
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Analogs of aminoglutethimide: selective inhibition of aromatase

Foster, Allan B ; Jarman, Michael ; Leung, Chui Sheung ; Rowlands, Martin G ; Taylor, Grahame N

Journal of medicinal chemistry, 1985-02, Vol.28 (2), p.200-204 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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6
Analogs of 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione as selective inhibitors of aromatase: derivatives with variable 1-alkyl and 3-alkyl substituents
Analogs of 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione as selective inhibitors of aromatase: derivatives with variable 1-alkyl and 3-alkyl substituents
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Analogs of 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione as selective inhibitors of aromatase: derivatives with variable 1-alkyl and 3-alkyl substituents

Leung, Chui Sheung ; Rowlands, Martin G. ; Jarman, Michael ; Foster, Allan B. ; Griggs, Leslie J. ; Wilman, Derry E. V.

Journal of medicinal chemistry, 1987-09, Vol.30 (9), p.1550-1554 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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7
Homologs of Idoxifene:  Variation of Estrogen Receptor Binding and Calmodulin Antagonism with Chain Length
Homologs of Idoxifene:  Variation of Estrogen Receptor Binding and Calmodulin Antagonism with Chain Length
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Homologs of Idoxifene:  Variation of Estrogen Receptor Binding and Calmodulin Antagonism with Chain Length

Hardcastle, Ian R ; Rowlands, Martin G ; Grimshaw, Rachel M ; Houghton, John ; Jarman, Michael ; Sharff, Andrew ; Neidle, Stephen

Journal of medicinal chemistry, 1996-02, Vol.39 (4), p.999-1004 [Periódico revisado por pares]

United States: American Chemical Society

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8
Analogs of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity
Analogs of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity
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Analogs of aminoglutethimide based on 1-phenyl-3-azabicyclo[3.1.0]hexane-2,4-dione: selective inhibition of aromatase activity

Rowlands, Martin G ; Bunnett, Michael A ; Foster, Allan B ; Jarman, Michael ; Stanek, Jaroslav ; Schweizer, Ernst

Journal of medicinal chemistry, 1988-05, Vol.31 (5), p.971-976 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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9
Hydroxyperfluoroazobenzenes: novel inhibitors of enzymes of androgen biosynthesis
Hydroxyperfluoroazobenzenes: novel inhibitors of enzymes of androgen biosynthesis
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Hydroxyperfluoroazobenzenes: novel inhibitors of enzymes of androgen biosynthesis

Jarman, Michael ; Barrie, S. Elaine ; Deadman, John J ; Houghton, John ; McCague, Raymond ; Rowlands, Martin G

Journal of medicinal chemistry, 1990-09, Vol.33 (9), p.2452-2455 [Periódico revisado por pares]

United States: American Chemical Society

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10
Crystallographic and molecular modeling studies on 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione and its butyl analog, inhibitors of mammalian aromatase. Comparison with natural substrates: prediction of enantioselectivity for N-alkyl derivatives
Crystallographic and molecular modeling studies on 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione and its butyl analog, inhibitors of mammalian aromatase. Comparison with natural substrates: prediction of enantioselectivity for N-alkyl derivatives
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Crystallographic and molecular modeling studies on 3-ethyl-3-(4-pyridyl)piperidine-2,6-dione and its butyl analog, inhibitors of mammalian aromatase. Comparison with natural substrates: prediction of enantioselectivity for N-alkyl derivatives

Laughton, Charles A ; McKenna, Robert ; Neidle, Stephen ; Jarman, Michael ; McCague, Ray ; Rowlands, Martin G

Journal of medicinal chemistry, 1990-09, Vol.33 (9), p.2673-2679 [Periódico revisado por pares]

United States: American Chemical Society

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