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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2

Drayman, Nir ; DeMarco, Jennifer K ; Jones, Krysten A ; Azizi, Saara-Anne ; Froggatt, Heather M ; Tan, Kemin ; Maltseva, Natalia Ivanovna ; Chen, Siquan ; Nicolaescu, Vlad ; Dvorkin, Steve ; Furlong, Kevin ; Kathayat, Rahul S ; Firpo, Mason R ; Mastrodomenico, Vincent ; Bruce, Emily A ; Schmidt, Madaline M ; Jedrzejczak, Robert ; Muñoz-Alía, Miguel Á ; Schuster, Brooke ; Nair, Vishnu ; Han, Kyu-Yeon ; O'Brien, Amornrat ; Tomatsidou, Anastasia ; Meyer, Bjoern ; Vignuzzi, Marco ; Missiakas, Dominique ; Botten, Jason W ; Brooke, Christopher B ; Lee, Hyun ; Baker, Susan C ; Mounce, Bryan C ; Heaton, Nicholas S ; Severson, William E ; Palmer, Kenneth E ; Dickinson, Bryan C ; Joachimiak, Andrzej ; Randall, Glenn ; Tay, Savaş

Science (American Association for the Advancement of Science), 2021-08, Vol.373 (6557), p.931-936 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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2
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
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SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase

Zheng, Qinheng ; Woehl, Jordan L. ; Kitamura, Seiya ; Santos-Martins, Diogo ; Smedley, Christopher J. ; Li, Gencheng ; Forli, Stefano ; Moses, John E. ; Wolan, Dennis W. ; Sharpless, K. Barry

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (38), p.18808-18814 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets
Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets
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Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets

Sriram, Krishna ; Insel, Paul A

Physiological reviews, 2021-04, Vol.101 (2), p.545-567 [Periódico revisado por pares]

United States: American Physiological Society

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4
Proteasome inhibitors in multiple myeloma: 10 years later
Proteasome inhibitors in multiple myeloma: 10 years later
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Proteasome inhibitors in multiple myeloma: 10 years later

Moreau, Philippe ; Richardson, Paul G. ; Cavo, Michele ; Orlowski, Robert Z. ; San Miguel, Jesús F. ; Palumbo, Antonio ; Harousseau, Jean-Luc

Blood, 2012-08, Vol.120 (5), p.947-959 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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5
NSP4, an elastase-related protease in human neutrophils with arginine specificity
NSP4, an elastase-related protease in human neutrophils with arginine specificity
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NSP4, an elastase-related protease in human neutrophils with arginine specificity

Perera, Natascha C ; Schilling, Oliver ; Kittel, Heike ; Back, Walter ; Kremmer, Elisabeth ; Jenne, Dieter E

Proceedings of the National Academy of Sciences - PNAS, 2012-04, Vol.109 (16), p.6229-6234 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
Proteinase-activated Receptor 2: Springboard of Tumors
Proteinase-activated Receptor 2: Springboard of Tumors
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Proteinase-activated Receptor 2: Springboard of Tumors

Vetvicka, David ; Suhaj, Petr ; Olejar, Tomas ; Sivak, Ladislav ; Benes, Jiri ; Pouckova, Pavla

Anticancer research, 2024-01, Vol.44 (1), p.1-12 [Periódico revisado por pares]

Greece: International Institute of Anticancer Research

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7
Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali: conformation, selectin binding, and biological activity
Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali: conformation, selectin binding, and biological activity
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Fucosylated chondroitin sulfates from the body wall of the sea cucumber Holothuria forskali: conformation, selectin binding, and biological activity

Panagos, Charalampos G ; Thomson, Derek S ; Moss, Claire ; Hughes, Adam D ; Kelly, Maeve S ; Liu, Yan ; Chai, Wengang ; Venkatasamy, Radhakrishnan ; Spina, Domenico ; Page, Clive P ; Hogwood, John ; Woods, Robert J ; Mulloy, Barbara ; Bavington, Charlie D ; Uhrín, Dušan

The Journal of biological chemistry, 2014-10, Vol.289 (41), p.28284-28298 [Periódico revisado por pares]

United States: American Society for Biochemistry and Molecular Biology

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8
Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1
Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1
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Synthesis of a sugar-based thiosemicarbazone series and structure-activity relationship versus the parasite cysteine proteases rhodesain, cruzain, and Schistosoma mansoni cathepsin B1

Fonseca, Nayara Cristina ; da Cruz, Luana Faria ; da Silva Villela, Filipe ; do Nascimento Pereira, Glaécia Aparecida ; de Siqueira-Neto, Jair Lage ; Kellar, Danielle ; Suzuki, Brian M ; Ray, Debalina ; de Souza, Thiago Belarmino ; Alves, Ricardo José ; Sales Júnior, Policarpo Ademar ; Romanha, Alvaro José ; Murta, Silvane Maria Fonseca ; McKerrow, James H ; Caffrey, Conor R ; de Oliveira, Renata Barbosa ; Ferreira, Rafaela Salgado

Antimicrobial agents and chemotherapy, 2015-05, Vol.59 (5), p.2666-2677 [Periódico revisado por pares]

United States: American Society for Microbiology

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9
Engineering a potent inhibitor of matriptase from the natural hepatocyte growth factor activator inhibitor type-1 (HAI-1) protein
Engineering a potent inhibitor of matriptase from the natural hepatocyte growth factor activator inhibitor type-1 (HAI-1) protein
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Engineering a potent inhibitor of matriptase from the natural hepatocyte growth factor activator inhibitor type-1 (HAI-1) protein

Mitchell, Aaron C. ; Kannan, Deepti ; Hunter, Sean A. ; Parra Sperberg, R. Andres ; Chang, Cheryl H. ; Cochran, Jennifer R.

The Journal of biological chemistry, 2018-04, Vol.293 (14), p.4969-4980 [Periódico revisado por pares]

United States: Elsevier Inc

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10
Effector Specialization in a Lineage of the Irish Potato Famine Pathogen
Effector Specialization in a Lineage of the Irish Potato Famine Pathogen
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Effector Specialization in a Lineage of the Irish Potato Famine Pathogen

Dong, Suomeng ; Stam, Remco ; Cano, Liliana M. ; Song, Jing ; Sklenar, Jan ; Yoshida, Kentaro ; Bozkurt, Tolga O. ; Oliva, Ricardo ; Liu, Zhenyu ; Tian, Miaoying ; Win, Joe ; Banfield, Mark J. ; Jones, Alexandra M. E. ; van der Hoorn, Renier A. L. ; Kamoun, Sophien

Science (American Association for the Advancement of Science), 2014-01, Vol.343 (6170), p.552-555 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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