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Material Type: Artigo
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Human α-Synuclein-Harboring Familial Parkinson's Disease-Linked Ala-53 → Thr Mutation Causes Neurodegenerative Disease with α-Synuclein Aggregation in Transgenic MiceLee, Michael K. ; Stirling, Wanda ; Xu, Yanqun ; Xu, Xueying ; Qui, Dike ; Mandir, Allen S. ; Dawson, Ted M. ; Copeland, Neal G. ; Jenkins, Nancy A. ; Price, Don L.Proceedings of the National Academy of Sciences - PNAS, 2002-06, Vol.99 (13), p.8968-8973 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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neurodegenerative disease mutation that accelerates the clearance of apoptotic cellsKao, Aimee W ; Eisenhut, Robin J ; Martens, Lauren Herl ; Nakamura, Ayumi ; Huang, Anne ; Bagley, Josh A ; Zhou, Ping ; de Luis, Alberto ; Neukomm, Lukas J ; Cabello, Juan ; Farese, Robert V. Jr ; Kenyon, CynthiaProceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (11), p.4441-4446 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Axonal Transport Defects in Neurodegenerative DiseasesMorfini, Gerardo A ; Burns, Matthew ; Binder, Lester I ; Kanaan, Nicholas M ; LaPointe, Nichole ; Bosco, Daryl A ; Brown, Robert H., Jr ; Brown, Hannah ; Tiwari, Ashutosh ; Hayward, Lawrence ; Edgar, Julia ; Nave, Klaus-Armin ; Garberrn, James ; Atagi, Yuka ; Song, Yuyu ; Pigino, Gustavo ; Brady, Scott TThe Journal of neuroscience, 2009-10, Vol.29 (41), p.12776-12786 [Periódico revisado por pares]United States: Soc NeuroscienceTexto completo disponível |
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Material Type: Artigo
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Small molecule C381 targets the lysosome to reduce inflammation and ameliorate disease in models of neurodegenerationVest, Ryan T ; Chou, Ching-Chieh ; Zhang, Hui ; Haney, Michael S ; Li, Lulin ; Laqtom, Nouf N ; Chang, Betty ; Shuken, Steven ; Nguyen, Andy ; Yerra, Lakshmi ; Yang, Andrew C ; Green, Carol ; Tanga, Mary ; Abu-Remaileh, Monther ; Bassik, Michael C ; Frydman, Judith ; Luo, Jian ; Wyss-Coray, TonyProceedings of the National Academy of Sciences - PNAS, 2022-03, Vol.119 (11), p.e2121609119-e2121609119 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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Drosophila as an In Vivo Model for Human Neurodegenerative DiseaseMcGurk, Leeanne ; Berson, Amit ; Bonini, Nancy MGenetics (Austin), 2015-10, Vol.201 (2), p.377-402 [Periódico revisado por pares]United States: Genetics Society of AmericaTexto completo disponível |
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Material Type: Artigo
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P7C3-A20 treatment one year after TBI in mice repairs the blood–brain barrier, arrests chronic neurodegeneration, and restores cognitionVázquez-Rosa, Edwin ; Shin, Min-Kyoo ; Dhar, Matasha ; Chaubey, Kalyani ; Cintrón-Pérez, Coral J. ; Tang, Xinmiao ; Liao, Xudong ; Miller, Emiko ; Koh, Yeojung ; Barker, Sarah ; Franke, Kathryn ; Crosby, Danyel R. ; Schroeder, Rachel ; Emery, Josie ; Yin, Terry C. ; Fujioka, Hisashi ; Reynolds, James D. ; Harper, Matthew M. ; Jain, Mukesh K. ; Pieper, Andrew A.Proceedings of the National Academy of Sciences - PNAS, 2020-11, Vol.117 (44), p.27667-27675 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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MicroRNA-223 is neuroprotective by targeting glutamate receptorsHarraz, Maged M ; Eacker, Stephen M ; Wang, Xueqing ; Dawson, Ted M ; Dawson, Valina LProceedings of the National Academy of Sciences - PNAS, 2012-11, Vol.109 (46), p.18962-18967 [Periódico revisado por pares]United States: National Academy of SciencesTexto completo disponível |
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Material Type: Artigo
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TCRD and Pharos 2021: mining the human proteome for disease biologySheils, Timothy K ; Mathias, Stephen L ; Kelleher, Keith J ; Siramshetty, Vishal B ; Nguyen, Dac-Trung ; Bologa, Cristian G ; Jensen, Lars Juhl ; Vidović, Dušica ; Koleti, Amar ; Schürer, Stephan C ; Waller, Anna ; Yang, Jeremy J ; Holmes, Jayme ; Bocci, Giovanni ; Southall, Noel ; Dharkar, Poorva ; Mathé, Ewy ; Simeonov, Anton ; Oprea, Tudor INucleic acids research, 2021-01, Vol.49 (D1), p.D1334-D1346 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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The LIMP-2/SCARB2 binding motif on acid β-glucosidase: basic and applied implications for Gaucher disease and associated neurodegenerative diseasesLiou, Benjamin ; Haffey, Wendy D ; Greis, Kenneth D ; Grabowski, Gregory AThe Journal of biological chemistry, 2014-10, Vol.289 (43), p.30063-30074 [Periódico revisado por pares]United States: American Society for Biochemistry and Molecular BiologyTexto completo disponível |
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Material Type: Artigo
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Sphingosine 1-phosphate: Lipid signaling in pathology and therapyCartier, Andreane ; Hla, TimothyScience (American Association for the Advancement of Science), 2019-10, Vol.366 (6463) [Periódico revisado por pares]United States: The American Association for the Advancement of ScienceTexto completo disponível |