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Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia
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Targeting BTK with Ibrutinib in Relapsed Chronic Lymphocytic Leukemia

Byrd, John C ; Furman, Richard R ; Coutre, Steven E ; Flinn, Ian W ; Burger, Jan A ; Blum, Kristie A ; Grant, Barbara ; Sharman, Jeff P ; Coleman, Morton ; Wierda, William G ; Jones, Jeffrey A ; Zhao, Weiqiang ; Heerema, Nyla A ; Johnson, Amy J ; Sukbuntherng, Juthamas ; Chang, Betty Y ; Clow, Fong ; Hedrick, Eric ; Buggy, Joseph J ; James, Danelle F ; O'Brien, Susan

The New England journal of medicine, 2013-07, Vol.369 (1), p.32-42 [Periódico revisado por pares]

Waltham, MA: Massachusetts Medical Society

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2
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study
Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study
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Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study

Larson, Richard A. ; Druker, Brian J. ; Guilhot, Francois ; O'Brien, Stephen G. ; Riviere, Gilles J. ; Krahnke, Tillmann ; Gathmann, Insa ; Wang, Yanfeng

Blood, 2008-04, Vol.111 (8), p.4022-4028 [Periódico revisado por pares]

Washington, DC: Elsevier Inc

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3
Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor
Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor
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Discovery and pharmacological characterization of N-[2-({2-[(2S)-2-cyanopyrrolidin-1-yl]-2-oxoethyl}amino)-2-methylpropyl]-2-methylpyrazolo[1,5-a]pyrimidine-6-carboxamide hydrochloride (anagliptin hydrochloride salt) as a potent and selective DPP-IV inhibitor

Kato, Noriyasu ; Oka, Mitsuru ; Murase, Takayo ; Yoshida, Masahiro ; Sakairi, Masao ; Yamashita, Satoko ; Yasuda, Yoshika ; Yoshikawa, Aya ; Hayashi, Yuuji ; Makino, Mitsuhiro ; Takeda, Motohiro ; Mirensha, Yakufu ; Kakigami, Takuji

Bioorganic & medicinal chemistry, 2011-12, Vol.19 (23), p.7221-7227 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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4
Nilotinib versus Imatinib for Newly Diagnosed Chronic Myeloid Leukemia
Nilotinib versus Imatinib for Newly Diagnosed Chronic Myeloid Leukemia
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Nilotinib versus Imatinib for Newly Diagnosed Chronic Myeloid Leukemia

Saglio, Giuseppe ; Kim, Dong-Wook ; Issaragrisil, Surapol ; le Coutre, Philipp ; Etienne, Gabriel ; Lobo, Clarisse ; Pasquini, Ricardo ; Clark, Richard E ; Hochhaus, Andreas ; Hughes, Timothy P ; Gallagher, Neil ; Hoenekopp, Albert ; Dong, Mei ; Haque, Ariful ; Larson, Richard A ; Kantarjian, Hagop M

The New England journal of medicine, 2010-06, Vol.362 (24), p.2251-2259 [Periódico revisado por pares]

Waltham, MA: Massachusetts Medical Society

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5
Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors: Focus on Pyrimidines, Pyridines and Pyrroles
Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors: Focus on Pyrimidines, Pyridines and Pyrroles
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Clinical Pharmacokinetics of Tyrosine Kinase Inhibitors: Focus on Pyrimidines, Pyridines and Pyrroles

Di Gion, Paola ; Kanefendt, Friederike ; Lindauer, Andreas ; Scheffler, Matthias ; Doroshyenko, Oxana ; Fuhr, Uwe ; Wolf, Jürgen ; Jaehde, Ulrich

Clinical pharmacokinetics, 2011-09, Vol.50 (9), p.551-603 [Periódico revisado por pares]

Cham: Springer International Publishing

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6
Synthesis and antitumor activity of new sulfonamide derivatives of thiadiazolo[3,2- a]pyrimidines
Synthesis and antitumor activity of new sulfonamide derivatives of thiadiazolo[3,2- a]pyrimidines
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Synthesis and antitumor activity of new sulfonamide derivatives of thiadiazolo[3,2- a]pyrimidines

El-Sayed, Nadia S. ; El-Bendary, Eman R. ; El-Ashry, Saadia M. ; El-Kerdawy, Mohammed M.

European journal of medicinal chemistry, 2011-09, Vol.46 (9), p.3714-3720 [Periódico revisado por pares]

Kidlington: Elsevier Masson SAS

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7
Synthesis, analgesic and anti-inflammatory activities evaluation of some bi-, tri- and tetracyclic condensed pyrimidines
Synthesis, analgesic and anti-inflammatory activities evaluation of some bi-, tri- and tetracyclic condensed pyrimidines
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Synthesis, analgesic and anti-inflammatory activities evaluation of some bi-, tri- and tetracyclic condensed pyrimidines

Amin, Kamilia M. ; Hanna, Mona M. ; Abo-Youssef, Hanan E. ; George, Riham F.

European journal of medicinal chemistry, 2009-11, Vol.44 (11), p.4572-4584 [Periódico revisado por pares]

Kidlington: Elsevier Masson SAS

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8
Phase II Study of Alisertib, a Selective Aurora A Kinase Inhibitor, in Relapsed and Refractory Aggressive B- and T-Cell Non-Hodgkin Lymphomas
Phase II Study of Alisertib, a Selective Aurora A Kinase Inhibitor, in Relapsed and Refractory Aggressive B- and T-Cell Non-Hodgkin Lymphomas
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Phase II Study of Alisertib, a Selective Aurora A Kinase Inhibitor, in Relapsed and Refractory Aggressive B- and T-Cell Non-Hodgkin Lymphomas

FRIEDBERG, Jonathan W ; MAHADEVAN, Daruka ; FINGERT, Howard ; DANAEE, Hadi ; BERNSTEIN, Steven H ; CEBULA, Erin ; PERSKY, Daniel ; LOSSOS, Izidore ; AGARWAL, Amit B ; JUNGAH JUNG ; BURACK, Richard ; XIAOFEI ZHOU ; LEONARD, E. Jane

Journal of clinical oncology, 2014-01, Vol.32 (1), p.44-50 [Periódico revisado por pares]

Alexandria, VA: American Society of Clinical Oncology

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9
Single step synthesis of new fused pyrimidine derivatives and their evaluation as potent Aurora-A kinase inhibitors
Single step synthesis of new fused pyrimidine derivatives and their evaluation as potent Aurora-A kinase inhibitors
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Single step synthesis of new fused pyrimidine derivatives and their evaluation as potent Aurora-A kinase inhibitors

Shaaban, Mohamed R. ; Saleh, Tamer S. ; Mayhoub, Abdelrahman S. ; Farag, Ahmad M.

European journal of medicinal chemistry, 2011-09, Vol.46 (9), p.3690-3695 [Periódico revisado por pares]

Kidlington: Elsevier Masson SAS

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10
Riociguat for the Treatment of Chronic Thromboembolic Pulmonary Hypertension
Riociguat for the Treatment of Chronic Thromboembolic Pulmonary Hypertension
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Riociguat for the Treatment of Chronic Thromboembolic Pulmonary Hypertension

Ghofrani, Hossein-Ardeschir ; D'Armini, Andrea M ; Grimminger, Friedrich ; Hoeper, Marius M ; Jansa, Pavel ; Kim, Nick H ; Mayer, Eckhard ; Simonneau, Gerald ; Wilkins, Martin R ; Fritsch, Arno ; Neuser, Dieter ; Weimann, Gerrit ; Wang, Chen

The New England journal of medicine, 2013-07, Vol.369 (4), p.319-329 [Periódico revisado por pares]

Waltham, MA: Massachusetts Medical Society

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