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Recharacterization of the mammalian cytosolic type 2 (R)-β-hydroxybutyrate dehydrogenase as 4-oxo-l-proline reductase (EC 1.1.1.104)
Recharacterization of the mammalian cytosolic type 2 (R)-β-hydroxybutyrate dehydrogenase as 4-oxo-l-proline reductase (EC 1.1.1.104)
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Recharacterization of the mammalian cytosolic type 2 (R)-β-hydroxybutyrate dehydrogenase as 4-oxo-l-proline reductase (EC 1.1.1.104)

Kwiatkowski, Sebastian ; Bozko, Maria ; Zarod, Michal ; Witecka, Apolonia ; Kocdemir, Kubra ; Jagielski, Adam K. ; Drozak, Jakub

The Journal of biological chemistry, 2022-03, Vol.298 (3), p.101708-101708, Article 101708 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Design and Mechanism of (S)‑3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ‑Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction
Design and Mechanism of (S)‑3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ‑Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction
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Design and Mechanism of (S)‑3-Amino-4-(difluoromethylenyl)cyclopent-1-ene-1-carboxylic Acid, a Highly Potent γ‑Aminobutyric Acid Aminotransferase Inactivator for the Treatment of Addiction

Juncosa, Jose I ; Takaya, Kenji ; Le, Hoang V ; Moschitto, Matthew J ; Weerawarna, Pathum M ; Mascarenhas, Romila ; Liu, Dali ; Dewey, Stephen L ; Silverman, Richard B

Journal of the American Chemical Society, 2018-02, Vol.140 (6), p.2151-2164 [Periódico revisado por pares]

United States: American Chemical Society

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3
The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A
The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A
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The Oxygen Sensor PHD2 Controls Dendritic Spines and Synapses via Modification of Filamin A

Segura, Inmaculada ; Lange, Christian ; Knevels, Ellen ; Moskalyuk, Anastasiya ; Pulizzi, Rocco ; Eelen, Guy ; Chaze, Thibault ; Tudor, Cicerone ; Boulegue, Cyril ; Holt, Matthew ; Daelemans, Dirk ; Matondo, Mariette ; Ghesquière, Bart ; Giugliano, Michele ; Ruiz de Almodovar, Carmen ; Dewerchin, Mieke ; Carmeliet, Peter

Cell reports (Cambridge), 2016-03, Vol.14 (11), p.2653-2667 [Periódico revisado por pares]

United States: Elsevier Inc

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4
PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban
PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban
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PHD2/3-dependent hydroxylation tunes cardiac response to β-adrenergic stress via phospholamban

Xie, Liang ; Pi, Xinchun ; Townley-Tilson, W H Davin ; Li, Na ; Wehrens, Xander H T ; Entman, Mark L ; Taffet, George E ; Mishra, Ashutosh ; Peng, Junmin ; Schisler, Jonathan C ; Meissner, Gerhard ; Patterson, Cam

The Journal of clinical investigation, 2015-07, Vol.125 (7), p.2759-2771 [Periódico revisado por pares]

United States: American Society for Clinical Investigation

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5
Characterization of Vixotrigine, a Broad-Spectrum Voltage-Gated Sodium Channel Blocker
Characterization of Vixotrigine, a Broad-Spectrum Voltage-Gated Sodium Channel Blocker
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Characterization of Vixotrigine, a Broad-Spectrum Voltage-Gated Sodium Channel Blocker

Hinckley, Christopher A ; Kuryshev, Yuri ; Sers, Alissende ; Barre, Alexander ; Buisson, Bruno ; Naik, Himanshu ; Hajos, Mihaly

Molecular pharmacology, 2021-01, Vol.99 (1), p.49-59 [Periódico revisado por pares]

United States

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6
Metabolism of Proline as Microenvironmental Stress Substrate
Metabolism of Proline as Microenvironmental Stress Substrate
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Metabolism of Proline as Microenvironmental Stress Substrate

Phang, James M ; Pandhare, Jui ; Liu, Yongmin

The Journal of nutrition, 2008-10, Vol.138 (10), p.2008S-2015S [Periódico revisado por pares]

Bethesda, MD: American Society for Nutrition

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7
Discovery of a Potent (4R,5S)‑4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling
Discovery of a Potent (4R,5S)‑4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling
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Discovery of a Potent (4R,5S)‑4-Fluoro-5-methylproline Sulfonamide Transient Receptor Potential Ankyrin 1 Antagonist and Its Methylene Phosphate Prodrug Guided by Molecular Modeling

Chen, Huifen ; Volgraf, Matthew ; Do, Steven ; Kolesnikov, Aleksandr ; Shore, Daniel G ; Verma, Vishal A ; Villemure, Elisia ; Wang, Lan ; Chen, Yong ; Hu, Baihua ; Lu, Ai-Jun ; Wu, Guosheng ; Xu, Xiaofeng ; Yuen, Po-wai ; Zhang, Yamin ; Erickson, Shawn D ; Dahl, Martin ; Brotherton-Pleiss, Christine ; Tay, Suzanne ; Ly, Justin Q ; Murray, Lesley J ; Chen, Jun ; Amm, Desiree ; Lange, Wienke ; Hackos, David H ; Reese, Rebecca M ; Shields, Shannon D ; Lyssikatos, Joseph P ; Safina, Brian S ; Estrada, Anthony A

Journal of medicinal chemistry, 2018-04, Vol.61 (8), p.3641-3659 [Periódico revisado por pares]

United States: American Chemical Society

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8
Synthesis and Evaluation of in Vivo Anti-hypothermic Effect of the N- and C-Terminus Modified Thyrotropin-Releasing Hormone Mimetic: [(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-[3-(thiazol-4-yl)-L-alanyl]-L-prolinamide
Synthesis and Evaluation of in Vivo Anti-hypothermic Effect of the N- and C-Terminus Modified Thyrotropin-Releasing Hormone Mimetic: [(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-[3-(thiazol-4-yl)-L-alanyl]-L-prolinamide
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Synthesis and Evaluation of in Vivo Anti-hypothermic Effect of the N- and C-Terminus Modified Thyrotropin-Releasing Hormone Mimetic: [(4S,5S)-(5-Methyl-2-oxooxazolidine-4-yl)carbonyl]-[3-(thiazol-4-yl)-L-alanyl]-L-prolinamide

Kobayashi, Naotake ; Sato, Norihito ; Sugita, Katsuji ; Kihara, Tsuyoshi ; Koike, Katsumi ; Sugawara, Tamio ; Tada, Yukio ; Yoshikawa, Takayoshi

Chemical and Pharmaceutical Bulletin, 2021/04/01, Vol.69(4), pp.314-324 [Periódico revisado por pares]

Japan: The Pharmaceutical Society of Japan

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9
Formulation, Characterisation and Evaluation of the Antihypertensive Peptides, Isoleucine-Proline-Proline and Leucine-Lysine-Proline in Chitosan Nanoparticles Coated with Zein for Oral Drug Delivery
Formulation, Characterisation and Evaluation of the Antihypertensive Peptides, Isoleucine-Proline-Proline and Leucine-Lysine-Proline in Chitosan Nanoparticles Coated with Zein for Oral Drug Delivery
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Formulation, Characterisation and Evaluation of the Antihypertensive Peptides, Isoleucine-Proline-Proline and Leucine-Lysine-Proline in Chitosan Nanoparticles Coated with Zein for Oral Drug Delivery

Khalid Danish, Minna ; Gleeson, John P ; Brayden, David J ; Byrne, Hugh J ; Frías, Jesus M ; Ryan, Sinéad M

International journal of molecular sciences, 2022-09, Vol.23 (19), p.11160 [Periódico revisado por pares]

Switzerland: MDPI AG

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10
Lactobacillus paracasei L9 affects disease progression in experimental autoimmune neuritis by regulating intestinal flora structure and arginine metabolism
Lactobacillus paracasei L9 affects disease progression in experimental autoimmune neuritis by regulating intestinal flora structure and arginine metabolism
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Lactobacillus paracasei L9 affects disease progression in experimental autoimmune neuritis by regulating intestinal flora structure and arginine metabolism

Meng, Yuting ; Qiu, Xiangjie ; Tang, Zhongxiang ; Mao, Yu ; Tan, Yurong

Journal of neuroinflammation, 2023-05, Vol.20 (1), p.122-122, Article 122 [Periódico revisado por pares]

England: BioMed Central Ltd

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