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Material Type: Artigo
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Transgenic mice carrying the apolipoprotein E3-Leiden gene exhibit hyperlipoproteinemiavan den Maagdenberg, A.M. ; Hofker, M.H. ; Krimpenfort, P.J. ; de Bruijn, I. ; van Vlijmen, B. ; van der Boom, H. ; Havekes, L.M. ; Frants, R.R.The Journal of biological chemistry, 1993-05, Vol.268 (14), p.10540-10545 [Periódico revisado por pares]Bethesda, MD: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Reversal of Hypercholesterolemia in Apolipoprotein E2 and Apolipoprotein E3-Leiden Transgenic Mice by Adenovirus-Mediated Gene Transfer of the VLDL Receptorvan Dijk, Ko Willems ; van Vlijmen, Bart J.M ; van der Zee, Andre ; van't Hof, Belinda ; van der Boom, Hans ; Kobayashi, Kunihisa ; Chan, Lawrence ; Havekes, Louis M ; Hofker, Marten HArteriosclerosis, thrombosis, and vascular biology, 1998-01, Vol.18 (1), p.7-12 [Periódico revisado por pares]Philadelphia, PA: American Heart Association, IncTexto completo disponível |
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Material Type: Artigo
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In the Absence of Endogenous Mouse Apolipoprotein E, Apolipoprotein E2(Arg-158 → Cys) Transgenic Mice Develop More Severe Hyperlipoproteinemia than Apolipoprotein E3-Leiden Transgenic Micevan Vlijmen, Bart J.M. ; van Dijk, Ko Willems ; van't Hof, H. Belinda ; van Gorp, Patrick J.J. ; van der Zee, André ; van der Boom, Hans ; Breuer, Marco L. ; Hofker, Marten H. ; Havekes, Louis M.The Journal of biological chemistry, 1996-11, Vol.271 (48), p.30595-30602 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Diet-induced hyperlipoproteinemia and atherosclerosis in apolipoprotein E3-Leiden transgenic miceVAN VLIJMEN, B. J. M ; VAN DEN MAAGDENBERG, A. M. J. M ; GIJBELS, M. J. J ; VAN DER BOOM, H ; HOGENESCH, H ; FRANTS, R. R ; HOFKER, M. H ; HAVEKES, L. MThe Journal of clinical investigation, 1994-04, Vol.93 (4), p.1403-1410 [Periódico revisado por pares]Ann Arbor, MI: American Society for Clinical InvestigationTexto completo disponível |
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Material Type: Artigo
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Modulation of very low density lipoprotein production and clearance contributes to age- and gender- dependent hyperlipoproteinemia in apolipoprotein E3-Leiden transgenic micevan Vlijmen, B J ; van 't Hof, H B ; Mol, M J ; van der Boom, H ; van der Zee, A ; Frants, R R ; Hofker, M H ; Havekes, L MThe Journal of clinical investigation, 1996-03, Vol.97 (5), p.1184-1192 [Periódico revisado por pares]United StatesTexto completo disponível |