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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Riva, Laura ; Yuan, Shuofeng ; Yin, Xin ; Martin-Sancho, Laura ; Matsunaga, Naoko ; Pache, Lars ; Burgstaller-Muehlbacher, Sebastian ; De Jesus, Paul D ; Teriete, Peter ; Hull, Mitchell V ; Chang, Max W ; Chan, Jasper Fuk-Woo ; Cao, Jianli ; Poon, Vincent Kwok-Man ; Herbert, Kristina M ; Cheng, Kuoyuan ; Nguyen, Tu-Trinh H ; Rubanov, Andrey ; Pu, Yuan ; Nguyen, Courtney ; Choi, Angela ; Rathnasinghe, Raveen ; Schotsaert, Michael ; Miorin, Lisa ; Dejosez, Marion ; Zwaka, Thomas P ; Sit, Ko-Yung ; Martinez-Sobrido, Luis ; Liu, Wen-Chun ; White, Kris M ; Chapman, Mackenzie E ; Lendy, Emma K ; Glynne, Richard J ; Albrecht, Randy ; Ruppin, Eytan ; Mesecar, Andrew D ; Johnson, Jeffrey R ; Benner, Christopher ; Sun, Ren ; Schultz, Peter G ; Su, Andrew I ; García-Sastre, Adolfo ; Chatterjee, Arnab K ; Yuen, Kwok-Yung ; Chanda, Sumit K

Nature (London), 2020-10, Vol.586 (7827), p.113-119 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2

Drayman, Nir ; DeMarco, Jennifer K ; Jones, Krysten A ; Azizi, Saara-Anne ; Froggatt, Heather M ; Tan, Kemin ; Maltseva, Natalia Ivanovna ; Chen, Siquan ; Nicolaescu, Vlad ; Dvorkin, Steve ; Furlong, Kevin ; Kathayat, Rahul S ; Firpo, Mason R ; Mastrodomenico, Vincent ; Bruce, Emily A ; Schmidt, Madaline M ; Jedrzejczak, Robert ; Muñoz-Alía, Miguel Á ; Schuster, Brooke ; Nair, Vishnu ; Han, Kyu-Yeon ; O'Brien, Amornrat ; Tomatsidou, Anastasia ; Meyer, Bjoern ; Vignuzzi, Marco ; Missiakas, Dominique ; Botten, Jason W ; Brooke, Christopher B ; Lee, Hyun ; Baker, Susan C ; Mounce, Bryan C ; Heaton, Nicholas S ; Severson, William E ; Palmer, Kenneth E ; Dickinson, Bryan C ; Joachimiak, Andrzej ; Randall, Glenn ; Tay, Savaş

Science (American Association for the Advancement of Science), 2021-08, Vol.373 (6557), p.931-936 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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3
A proteomic atlas of senescence-associated secretomes for aging biomarker development
A proteomic atlas of senescence-associated secretomes for aging biomarker development
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A proteomic atlas of senescence-associated secretomes for aging biomarker development

Basisty, Nathan ; Kale, Abhijit ; Jeon, Ok Hee ; Kuehnemann, Chisaka ; Payne, Therese ; Rao, Chirag ; Holtz, Anja ; Shah, Samah ; Sharma, Vagisha ; Ferrucci, Luigi ; Campisi, Judith ; Schilling, Birgit Serrano, Manuel

PLoS biology, 2020-01, Vol.18 (1), p.e3000599-e3000599 [Periódico revisado por pares]

United States: Public Library of Science

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4
A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic
A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic
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A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic

Shapira, Tirosh ; Monreal, I Abrrey ; Dion, Sébastien P ; Buchholz, David W ; Imbiakha, Brian ; Olmstead, Andrea D ; Jager, Mason ; Désilets, Antoine ; Gao, Guang ; Martins, Mathias ; Vandal, Thierry ; Thompson, Connor A H ; Chin, Aaleigha ; Rees, William D ; Steiner, Theodore ; Nabi, Ivan Robert ; Marsault, Eric ; Sahler, Julie ; Diel, Diego G ; Van de Walle, Gerlinde R ; August, Avery ; Whittaker, Gary R ; Boudreault, Pierre-Luc ; Leduc, Richard ; Aguilar, Hector C ; Jean, François

Nature (London), 2022-05, Vol.605 (7909), p.340-348 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Identification of highly selective covalent inhibitors by phage display
Identification of highly selective covalent inhibitors by phage display
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Identification of highly selective covalent inhibitors by phage display

Chen, Shiyu ; Lovell, Scott ; Lee, Sumin ; Fellner, Matthias ; Mace, Peter D ; Bogyo, Matthew

Nature biotechnology, 2021-04, Vol.39 (4), p.490-498 [Periódico revisado por pares]

United States: Nature Publishing Group

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6
Effector Specialization in a Lineage of the Irish Potato Famine Pathogen
Effector Specialization in a Lineage of the Irish Potato Famine Pathogen
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Effector Specialization in a Lineage of the Irish Potato Famine Pathogen

Dong, Suomeng ; Stam, Remco ; Cano, Liliana M. ; Song, Jing ; Sklenar, Jan ; Yoshida, Kentaro ; Bozkurt, Tolga O. ; Oliva, Ricardo ; Liu, Zhenyu ; Tian, Miaoying ; Win, Joe ; Banfield, Mark J. ; Jones, Alexandra M. E. ; van der Hoorn, Renier A. L. ; Kamoun, Sophien

Science (American Association for the Advancement of Science), 2014-01, Vol.343 (6170), p.552-555 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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7
An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus
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An NS3 protease inhibitor with antiviral effects in humans infected with hepatitis C virus

Lamarre, Daniel ; Anderson, Paul C ; Bailey, Murray ; Beaulieu, Pierre ; Bolger, Gordon ; Bonneau, Pierre ; Bös, Michael ; Cameron, Dale R ; Cartier, Mireille ; Cordingley, Michael G ; Faucher, Anne-Marie ; Goudreau, Nathalie ; Kawai, Stephen H ; Kukolj, George ; Lagacé, Lisette ; LaPlante, Steven R ; Narjes, Hans ; Poupart, Marc-André ; Rancourt, Jean ; Sentjens, Roel E ; St George, Roger ; Simoneau, Bruno ; Steinmann, Gerhard ; Thibeault, Diane ; Tsantrizos, Youla S ; Weldon, Steven M ; Yong, Chan-Loi ; Llinàs-Brunet, Montse

Nature, 2003-11, Vol.426 (6963), p.186-189 [Periódico revisado por pares]

London: Nature Publishing

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8
Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides
Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides
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Damage on plants activates Ca2+-dependent metacaspases for release of immunomodulatory peptides

Hander Tim ; Fernández-Fernández, Álvaro D ; Kumpf, Robert P ; Willems, Patrick ; Schatowitz Hendrik ; Rombaut Debbie ; Staes An ; Nolf Jonah ; Pottie, Robin ; Yao Panfeng ; Gonçalves, Amanda ; Pavie Benjamin ; Boller, Thomas ; Gevaert Kris ; Frank, Van Breusegem ; Bartels, Sebastian ; Stael Simon

Science (American Association for the Advancement of Science), 2019-03, Vol.363 (6433) [Periódico revisado por pares]

Washington: The American Association for the Advancement of Science

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9
Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes
Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes
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Functional degradation: A mechanism of NLRP1 inflammasome activation by diverse pathogen enzymes

Sandstrom, Andrew ; Mitchell, Patrick S ; Goers, Lisa ; Mu, Edward W ; Lesser, Cammie F ; Vance, Russell E

Science (American Association for the Advancement of Science), 2019-04, Vol.364 (6435) [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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10
Loss of hepatocyte growth factor activator inhibitor type 1 participates in metastatic spreading of human pancreatic cancer cells in a mouse orthotopic transplantation model
Loss of hepatocyte growth factor activator inhibitor type 1 participates in metastatic spreading of human pancreatic cancer cells in a mouse orthotopic transplantation model
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Loss of hepatocyte growth factor activator inhibitor type 1 participates in metastatic spreading of human pancreatic cancer cells in a mouse orthotopic transplantation model

Ye, Jingjia ; Kawaguchi, Makiko ; Haruyama, Yukihiro ; Kanemaru, Ai ; Fukushima, Tsuyoshi ; Yamamoto, Koji ; Lin, Chen‐Yong ; Kataoka, Hiroaki

Cancer science, 2014-01, Vol.105 (1), p.44-51 [Periódico revisado por pares]

England: John Wiley & Sons, Inc

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