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1
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
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Artigo
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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Riva, Laura ; Yuan, Shuofeng ; Yin, Xin ; Martin-Sancho, Laura ; Matsunaga, Naoko ; Pache, Lars ; Burgstaller-Muehlbacher, Sebastian ; De Jesus, Paul D ; Teriete, Peter ; Hull, Mitchell V ; Chang, Max W ; Chan, Jasper Fuk-Woo ; Cao, Jianli ; Poon, Vincent Kwok-Man ; Herbert, Kristina M ; Cheng, Kuoyuan ; Nguyen, Tu-Trinh H ; Rubanov, Andrey ; Pu, Yuan ; Nguyen, Courtney ; Choi, Angela ; Rathnasinghe, Raveen ; Schotsaert, Michael ; Miorin, Lisa ; Dejosez, Marion ; Zwaka, Thomas P ; Sit, Ko-Yung ; Martinez-Sobrido, Luis ; Liu, Wen-Chun ; White, Kris M ; Chapman, Mackenzie E ; Lendy, Emma K ; Glynne, Richard J ; Albrecht, Randy ; Ruppin, Eytan ; Mesecar, Andrew D ; Johnson, Jeffrey R ; Benner, Christopher ; Sun, Ren ; Schultz, Peter G ; Su, Andrew I ; García-Sastre, Adolfo ; Chatterjee, Arnab K ; Yuen, Kwok-Yung ; Chanda, Sumit K

Nature (London), 2020-10, Vol.586 (7827), p.113-119 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
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Artigo
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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2

Drayman, Nir ; DeMarco, Jennifer K ; Jones, Krysten A ; Azizi, Saara-Anne ; Froggatt, Heather M ; Tan, Kemin ; Maltseva, Natalia Ivanovna ; Chen, Siquan ; Nicolaescu, Vlad ; Dvorkin, Steve ; Furlong, Kevin ; Kathayat, Rahul S ; Firpo, Mason R ; Mastrodomenico, Vincent ; Bruce, Emily A ; Schmidt, Madaline M ; Jedrzejczak, Robert ; Muñoz-Alía, Miguel Á ; Schuster, Brooke ; Nair, Vishnu ; Han, Kyu-Yeon ; O'Brien, Amornrat ; Tomatsidou, Anastasia ; Meyer, Bjoern ; Vignuzzi, Marco ; Missiakas, Dominique ; Botten, Jason W ; Brooke, Christopher B ; Lee, Hyun ; Baker, Susan C ; Mounce, Bryan C ; Heaton, Nicholas S ; Severson, William E ; Palmer, Kenneth E ; Dickinson, Bryan C ; Joachimiak, Andrzej ; Randall, Glenn ; Tay, Savaş

Science (American Association for the Advancement of Science), 2021-08, Vol.373 (6557), p.931-936 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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3
Characterization of a serine protease inhibitor from Trichinella spiralis and its participation in larval invasion of host's intestinal epithelial cells
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Artigo
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Characterization of a serine protease inhibitor from Trichinella spiralis and its participation in larval invasion of host's intestinal epithelial cells

Song, Yan Yan ; Zhang, Yao ; Ren, Hua Nan ; Sun, Ge Ge ; Qi, Xin ; Yang, Fan ; Jiang, Peng ; Zhang, Xi ; Cui, Jing ; Wang, Zhong Quan

Parasites & vectors, 2018-09, Vol.11 (1), p.499-499, Article 499 [Periódico revisado por pares]

England: BioMed Central Ltd

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4
Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets
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Artigo
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Inflammation and thrombosis in COVID-19 pathophysiology: proteinase-activated and purinergic receptors as drivers and candidate therapeutic targets

Sriram, Krishna ; Insel, Paul A

Physiological reviews, 2021-04, Vol.101 (2), p.545-567 [Periódico revisado por pares]

United States: American Physiological Society

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5
A proteomic atlas of senescence-associated secretomes for aging biomarker development
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A proteomic atlas of senescence-associated secretomes for aging biomarker development

Basisty, Nathan ; Kale, Abhijit ; Jeon, Ok Hee ; Kuehnemann, Chisaka ; Payne, Therese ; Rao, Chirag ; Holtz, Anja ; Shah, Samah ; Sharma, Vagisha ; Ferrucci, Luigi ; Campisi, Judith ; Schilling, Birgit Serrano, Manuel

PLoS biology, 2020-01, Vol.18 (1), p.e3000599-e3000599 [Periódico revisado por pares]

United States: Public Library of Science

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6
A Retrospective Analysis of the Cartilage Kunitz Protease Inhibitory Proteins Identifies These as Members of the Inter-α-Trypsin Inhibitor Superfamily with Potential Roles in the Protection of the Articulatory Surface
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Artigo
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A Retrospective Analysis of the Cartilage Kunitz Protease Inhibitory Proteins Identifies These as Members of the Inter-α-Trypsin Inhibitor Superfamily with Potential Roles in the Protection of the Articulatory Surface

Smith, Susan M ; Melrose, James

International journal of molecular sciences, 2019-01, Vol.20 (3), p.497 [Periódico revisado por pares]

Switzerland: MDPI AG

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7
Tick Salivary Kunitz-Type Inhibitors: Targeting Host Hemostasis and Immunity to Mediate Successful Blood Feeding
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Artigo
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Tick Salivary Kunitz-Type Inhibitors: Targeting Host Hemostasis and Immunity to Mediate Successful Blood Feeding

Jmel, Mohamed Amine ; Voet, Hanne ; Araújo, Ricardo N ; Tirloni, Lucas ; Sá-Nunes, Anderson ; Kotsyfakis, Michail

International journal of molecular sciences, 2023-01, Vol.24 (2), p.1556 [Periódico revisado por pares]

Switzerland: MDPI AG

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8
A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic
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Artigo
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A TMPRSS2 inhibitor acts as a pan-SARS-CoV-2 prophylactic and therapeutic

Shapira, Tirosh ; Monreal, I Abrrey ; Dion, Sébastien P ; Buchholz, David W ; Imbiakha, Brian ; Olmstead, Andrea D ; Jager, Mason ; Désilets, Antoine ; Gao, Guang ; Martins, Mathias ; Vandal, Thierry ; Thompson, Connor A H ; Chin, Aaleigha ; Rees, William D ; Steiner, Theodore ; Nabi, Ivan Robert ; Marsault, Eric ; Sahler, Julie ; Diel, Diego G ; Van de Walle, Gerlinde R ; August, Avery ; Whittaker, Gary R ; Boudreault, Pierre-Luc ; Leduc, Richard ; Aguilar, Hector C ; Jean, François

Nature (London), 2022-05, Vol.605 (7909), p.340-348 [Periódico revisado por pares]

England: Nature Publishing Group

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9
Differential responses to low salinity on gene expression, physiological and biochemical indexes between the golden and brown noble scallops Chlamys nobilis
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Artigo
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Differential responses to low salinity on gene expression, physiological and biochemical indexes between the golden and brown noble scallops Chlamys nobilis

Wang, Ningli ; Yang, Jianqin ; Zhang, Hongkuan ; Soon, Tan Kar ; Liu, Hongxing ; Li, Shengkang ; Ma, Hongyu ; Zheng, Huaiping

Aquaculture research, 2020-01, Vol.51 (1), p.316-325 [Periódico revisado por pares]

Oxford: Hindawi Limited

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10
Autophagosomes accumulation in the vacuoles of the fungus Ustilago maydis and the role of proteases in their digestion
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Artigo
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Autophagosomes accumulation in the vacuoles of the fungus Ustilago maydis and the role of proteases in their digestion

Soberanes-Gutiérrez, Cinthia V ; Vázquez-Carrada, Melissa ; López-Villegas, Edgar O ; Vega-Arreguín, Julio C ; Villa-Tanaca, Lourdes ; Ruiz-Herrera, José

FEMS microbiology letters, 2019-05, Vol.366 (10), p.1 [Periódico revisado por pares]

England: Oxford University Press

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