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Refinado por: Base de dados/Biblioteca: EBSCO_MEDLINE Complete（医学期刊全文数据库） remover Nome da Publicação: Journal Of Pharmaceutical Sciences remover
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1
Identification of Acyl-Protein Thioesterase-1 as a Polysorbate-degrading Host Cell Protein in a Monoclonal Antibody Formulation Using Activity-based Protein Profiling
Identification of Acyl-Protein Thioesterase-1 as a Polysorbate-degrading Host Cell Protein in a Monoclonal Antibody Formulation Using Activity-based Protein Profiling
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Identification of Acyl-Protein Thioesterase-1 as a Polysorbate-degrading Host Cell Protein in a Monoclonal Antibody Formulation Using Activity-based Protein Profiling

Šprager, Ernest ; Möller, Jens ; Lin, Yuhsien ; Reisinger, Veronika ; Bratkovič, Tomaž ; Lunder, Mojca ; Vašl, Jožica ; Krajnc, Aleksander

Journal of pharmaceutical sciences, 2024-05 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Rapid Polysorbate 80 Degradation by Liver Carboxylesterase in a Monoclonal Antibody Formulated Drug Substance at Early Stage Development
Rapid Polysorbate 80 Degradation by Liver Carboxylesterase in a Monoclonal Antibody Formulated Drug Substance at Early Stage Development
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Rapid Polysorbate 80 Degradation by Liver Carboxylesterase in a Monoclonal Antibody Formulated Drug Substance at Early Stage Development

Zhang, Sisi ; Xiao, Hui ; Molden, Rosalynn ; Qiu, Haibo ; Li, Ning

Journal of pharmaceutical sciences, 2020-11, Vol.109 (11), p.3300-3307 [Periódico revisado por pares]

Elsevier Inc

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3
Identification and Characterization of Polysorbate-Degrading Enzymes in a Monoclonal Antibody Formulation
Identification and Characterization of Polysorbate-Degrading Enzymes in a Monoclonal Antibody Formulation
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Identification and Characterization of Polysorbate-Degrading Enzymes in a Monoclonal Antibody Formulation

Graf, Tobias ; Tomlinson, Anthony ; Yuk, Inn H. ; Kufer, Regina ; Spensberger, Bernhard ; Falkenstein, Roberto ; Shen, Amy ; Li, Hong ; Duan, Dana ; Liu, Wenqiang ; Wohlrab, Stefanie ; Edelmann, Franziska ; Leiss, Michael

Journal of pharmaceutical sciences, 2021-11, Vol.110 (11), p.3558-3567 [Periódico revisado por pares]

Elsevier Inc

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4
Ubiquitin: Characterization of a Host Cell Protein Covalently Attached to a Monoclonal Antibody Product by LC-MS/MS
Ubiquitin: Characterization of a Host Cell Protein Covalently Attached to a Monoclonal Antibody Product by LC-MS/MS
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Ubiquitin: Characterization of a Host Cell Protein Covalently Attached to a Monoclonal Antibody Product by LC-MS/MS

Kufer, Regina ; Larraillet, Vincent ; Thalhauser, Sabrina ; Graf, Tobias ; Endesfelder, Manuel ; Wohlrab, Stefanie

Journal of pharmaceutical sciences, 2024-06, Vol.113 (6), p.1470-1477 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Quantitative Assessment of the Impact of Crohn's Disease on Protein Abundance of Human Intestinal Drug-Metabolising Enzymes and Transporters
Quantitative Assessment of the Impact of Crohn's Disease on Protein Abundance of Human Intestinal Drug-Metabolising Enzymes and Transporters
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Quantitative Assessment of the Impact of Crohn's Disease on Protein Abundance of Human Intestinal Drug-Metabolising Enzymes and Transporters

Alrubia, Sarah ; Al-Majdoub, Zubida M. ; Achour, Brahim ; Rostami-Hodjegan, Amin ; Barber, Jill

Journal of pharmaceutical sciences, 2022-10, Vol.111 (10), p.2917-2929 [Periódico revisado por pares]

Elsevier Inc

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6
4-Hydroxynonenal is An Oxidative Degradation Product of Polysorbate 80
4-Hydroxynonenal is An Oxidative Degradation Product of Polysorbate 80
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4-Hydroxynonenal is An Oxidative Degradation Product of Polysorbate 80

Schröter, Ariane ; Koulov, Atanas V. ; Huwyler, Jörg ; Mahler, Hanns-Christian ; Jahn, Michael

Journal of pharmaceutical sciences, 2021-06, Vol.110 (6), p.2524-2530 [Periódico revisado por pares]

United States: Elsevier Inc

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7
Tryptophan Oxidation of a Monoclonal Antibody Under Diverse Oxidative Stress Conditions: Distinct Oxidative Pathways Favor Specific Tryptophan Residues
Tryptophan Oxidation of a Monoclonal Antibody Under Diverse Oxidative Stress Conditions: Distinct Oxidative Pathways Favor Specific Tryptophan Residues
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Tryptophan Oxidation of a Monoclonal Antibody Under Diverse Oxidative Stress Conditions: Distinct Oxidative Pathways Favor Specific Tryptophan Residues

Jacobitz, Alex W. ; Liu, Qian ; Suravajjala, Sreekanth ; Agrawal, Neeraj J.

Journal of pharmaceutical sciences, 2021-02, Vol.110 (2), p.719-726 [Periódico revisado por pares]

United States: Elsevier Inc

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8
An Automated and Qualified Platform Method for Site-Specific Succinimide and Deamidation Quantitation Using Low-pH Peptide Mapping
An Automated and Qualified Platform Method for Site-Specific Succinimide and Deamidation Quantitation Using Low-pH Peptide Mapping
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An Automated and Qualified Platform Method for Site-Specific Succinimide and Deamidation Quantitation Using Low-pH Peptide Mapping

Cao, Mingyan ; Xu, Weichen ; Niu, Ben ; Kabundi, Ivy ; Luo, Haibin ; Prophet, Meagan ; Chen, Weimin ; Liu, Dengfeng ; Saveliev, Sergei V. ; Urh, Marjeta ; Wang, Jihong

Journal of pharmaceutical sciences, 2019-11, Vol.108 (11), p.3540-3549 [Periódico revisado por pares]

United States: Elsevier Inc

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9
Characterization of Photodegradation Products of Bepotastine Besilate and In Silico Evaluation of Their Physicochemical, Absorption, Distribution, Metabolism, Excretion and Toxicity Properties
Characterization of Photodegradation Products of Bepotastine Besilate and In Silico Evaluation of Their Physicochemical, Absorption, Distribution, Metabolism, Excretion and Toxicity Properties
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Characterization of Photodegradation Products of Bepotastine Besilate and In Silico Evaluation of Their Physicochemical, Absorption, Distribution, Metabolism, Excretion and Toxicity Properties

Singh, Dilip Kumar ; Sahu, Archana ; Wani, Aabid Abdullah ; Bharatam, Prasad V. ; Chakraborti, Asit K. ; Giri, Sanjeev ; Singh, Saranjit

Journal of pharmaceutical sciences, 2020-06, Vol.109 (6), p.1883-1895 [Periódico revisado por pares]

United States: Elsevier Inc

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10
4-Hydroxynonenal – A Toxic Leachable from Clinically Used Administration Materials
4-Hydroxynonenal – A Toxic Leachable from Clinically Used Administration Materials
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4-Hydroxynonenal – A Toxic Leachable from Clinically Used Administration Materials

Schröter, Ariane ; Mahler, Hanns-Christian ; Sayed, Nadia Ben ; Koulov, Atanas V. ; Huwyler, Jörg ; Jahn, Michael

Journal of pharmaceutical sciences, 2021-09, Vol.110 (9), p.3268-3275 [Periódico revisado por pares]

Elsevier Inc

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