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Analysis of Large-Scale Mutagenesis Data To Assess the Impact of Single Amino Acid Substitutions
Analysis of Large-Scale Mutagenesis Data To Assess the Impact of Single Amino Acid Substitutions
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Analysis of Large-Scale Mutagenesis Data To Assess the Impact of Single Amino Acid Substitutions

Gray, Vanessa E ; Hause, Ronald J ; Fowler, Douglas M

Genetics (Austin), 2017-09, Vol.207 (1), p.53-61 [Periódico revisado por pares]

United States: Genetics Society of America

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2
Massively Parallel Functional Analysis of BRCA1 RING Domain Variants
Massively Parallel Functional Analysis of BRCA1 RING Domain Variants
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Massively Parallel Functional Analysis of BRCA1 RING Domain Variants

Starita, Lea M ; Young, David L ; Islam, Muhtadi ; Kitzman, Jacob O ; Gullingsrud, Justin ; Hause, Ronald J ; Fowler, Douglas M ; Parvin, Jeffrey D ; Shendure, Jay ; Fields, Stanley

Genetics (Austin), 2015-06, Vol.200 (2), p.413-422 [Periódico revisado por pares]

United States: Genetics Society of America

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3
fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function
fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function
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fundamental protein property, thermodynamic stability, revealed solely from large-scale measurements of protein function

Araya, Carlos L ; Fowler, Douglas M ; Chen, Wentao ; Muniez, Ike ; Kelly, Jeffery W ; Fields, Stanley

Proceedings of the National Academy of Sciences - PNAS, 2012-10, Vol.109 (42), p.16858-16863 [Periódico revisado por pares]

United States: National Academy of Sciences

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4
Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites
Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites
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Competitive organelle-specific adaptors recruit Vps13 to membrane contact sites

Bean, Björn D M ; Dziurdzik, Samantha K ; Kolehmainen, Kathleen L ; Fowler, Claire M S ; Kwong, Waldan K ; Grad, Leslie I ; Davey, Michael ; Schluter, Cayetana ; Conibear, Elizabeth

The Journal of cell biology, 2018-10, Vol.217 (10), p.3593-3607 [Periódico revisado por pares]

United States: Rockefeller University Press

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5
Megakaryocyte migration defects due to nonmuscle myosin IIA mutations underlie thrombocytopenia in MYH9-related disease
Megakaryocyte migration defects due to nonmuscle myosin IIA mutations underlie thrombocytopenia in MYH9-related disease
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Megakaryocyte migration defects due to nonmuscle myosin IIA mutations underlie thrombocytopenia in MYH9-related disease

Pal, Kasturi ; Nowak, Roberta ; Billington, Neil ; Liu, Rong ; Ghosh, Arit ; Sellers, James R. ; Fowler, Velia M.

Blood, 2020-05, Vol.135 (21), p.1887-1898 [Periódico revisado por pares]

United States: Elsevier Inc

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6
Comprehensive exploration of the translocation, stability and substrate recognition requirements in VIM-2 lactamase
Comprehensive exploration of the translocation, stability and substrate recognition requirements in VIM-2 lactamase
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Comprehensive exploration of the translocation, stability and substrate recognition requirements in VIM-2 lactamase

Chen, John Z ; Fowler, Douglas M ; Tokuriki, Nobuhiko

eLife, 2020-06, Vol.9 [Periódico revisado por pares]

England: eLife Science Publications, Ltd

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7
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis
Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis
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Activity-enhancing mutations in an E3 ubiquitin ligase identified by high-throughput mutagenesis

Starita, Lea M. ; Pruneda, Jonathan N. ; Lo, Russell S. ; Fowler, Douglas M. ; Kim, Helen J. ; Hiatt, Joseph B. ; Shendure, Jay ; Brzovic, Peter S. ; Fields, Stanley ; Klevit, Rachel E.

Proceedings of the National Academy of Sciences - PNAS, 2013-04, Vol.110 (14), p.5287-5287 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Early emergence of negative regulation of the tyrosine kinase Src by the C-terminal Src kinase
Early emergence of negative regulation of the tyrosine kinase Src by the C-terminal Src kinase
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Early emergence of negative regulation of the tyrosine kinase Src by the C-terminal Src kinase

Taskinen, Barbara ; Ferrada, Evandro ; Fowler, Douglas M.

The Journal of biological chemistry, 2017-11, Vol.292 (45), p.18518-18529 [Periódico revisado por pares]

United States: Elsevier Inc

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9
Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact
Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact
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Multiplexed measurement of variant abundance and activity reveals VKOR topology, active site and human variant impact

Chiasson, Melissa A ; Rollins, Nathan J ; Stephany, Jason J ; Sitko, Katherine A ; Matreyek, Kenneth A ; Verby, Marta ; Sun, Song ; Roth, Frederick P ; DeSloover, Daniel ; Marks, Debora S ; Rettie, Allan E ; Fowler, Douglas M

eLife, 2020-09, Vol.9 [Periódico revisado por pares]

England: eLife Science Publications, Ltd

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10
Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome
Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome
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Tropomodulin 1 controls erythroblast enucleation via regulation of F-actin in the enucleosome

Nowak, Roberta B. ; Papoin, Julien ; Gokhin, David S. ; Casu, Carla ; Rivella, Stefano ; Lipton, Jeffrey M. ; Blanc, Lionel ; Fowler, Velia M.

Blood, 2017-08, Vol.130 (9), p.1144-1155 [Periódico revisado por pares]

United States: Elsevier Inc

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