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Systematic in silico analysis of clinically tested drugs for reducing amyloid‐beta plaque accumulation in Alzheimer's disease
Systematic in silico analysis of clinically tested drugs for reducing amyloid‐beta plaque accumulation in Alzheimer's disease
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Systematic in silico analysis of clinically tested drugs for reducing amyloid‐beta plaque accumulation in Alzheimer's disease

Madrasi, Kumpal ; Das, Raibatak ; Mohmmadabdul, Hafiz ; Lin, Lin ; Hyman, Bradley T. ; Lauffenburger, Douglas A. ; Albers, Mark W. ; Rissman, Robert A. ; Burke, John M. ; Apgar, Joshua F. ; Wille, Lucia ; Gruenbaum, Lore ; Hua, Fei

Alzheimer's & dementia, 2021-09, Vol.17 (9), p.1487-1498 [Periódico revisado por pares]

United States: John Wiley and Sons Inc

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2
Quantitative systems pharmacology modeling provides insight into inter‐mouse variability of Anti‐CTLA4 response
Quantitative systems pharmacology modeling provides insight into inter‐mouse variability of Anti‐CTLA4 response
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Quantitative systems pharmacology modeling provides insight into inter‐mouse variability of Anti‐CTLA4 response

Qiao, Wenlian ; Lin, Lin ; Young, Carissa ; Narula, Jatin ; Hua, Fei ; Matteson, Andrew ; Hooper, Andrea ; Gruenbaum, Lore ; Betts, Alison

CPT: Pharmacometrics & Systems Pharmacology, 2022-07, Vol.11 (7), p.880-893 [Periódico revisado por pares]

United States: John Wiley & Sons, Inc

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3
Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B
Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B
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Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B

Fletcher, Simon P ; Chin, Daniel J ; Gruenbaum, Lore ; Bitter, Hans ; Rasmussen, Erik ; Ravindran, Palanikumar ; Swinney, David C ; Birzele, Fabian ; Schmucki, Roland ; Lorenz, Stefan H ; Kopetzki, Erhard ; Carter, Jade ; Triyatni, Miriam ; Thampi, Linta M ; Yang, Junming ; AlDeghaither, Dalal ; Murreddu, Marta G ; Murredu, Marta G ; Cote, Paul ; Menne, Stephan Robek, Michael D

PLoS pathogens, 2015-09, Vol.11 (9), p.e1005103 [Periódico revisado por pares]

United States: Public Library of Science

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4
Quantitative systems pharmacology model of GITR‐mediated T cell dynamics in tumor microenvironment
Quantitative systems pharmacology model of GITR‐mediated T cell dynamics in tumor microenvironment
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Quantitative systems pharmacology model of GITR‐mediated T cell dynamics in tumor microenvironment

Ji, Yan ; Madrasi, Kumpal ; Knee, Deborah A. ; Gruenbaum, Lore ; Apgar, Joshua F. ; Burke, John M. ; Gomes, Bruce

CPT: Pharmacometrics & Systems Pharmacology, 2023-03, Vol.12 (3), p.413-424 [Periódico revisado por pares]

United States: John Wiley & Sons, Inc

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5
Anti-spike T-cell and Antibody Responses to SARS-CoV-2 mRNA Vaccines in Patients with Hematologic Malignancies
Anti-spike T-cell and Antibody Responses to SARS-CoV-2 mRNA Vaccines in Patients with Hematologic Malignancies
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Anti-spike T-cell and Antibody Responses to SARS-CoV-2 mRNA Vaccines in Patients with Hematologic Malignancies

Greenberger, Lee M ; Saltzman, Larry A ; Gruenbaum, Lore M ; Xu, Jun ; Reddy, Sneha T ; Senefeld, Jonathon W ; Johnson, Patrick W ; Fields, Paul A ; Sanders, Catherine ; DeGennaro, Louis J ; Nichols, Gwen L

Blood cancer discovery, 2022-11, Vol.3 (6), p.481-489 [Periódico revisado por pares]

United States: American Association for Cancer Research

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6
Correction: Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B
Correction: Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B
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Correction: Intrahepatic Transcriptional Signature Associated with Response to Interferon-α Treatment in the Woodchuck Model of Chronic Hepatitis B

Fletcher, Simon P ; Chin, Daniel J ; Gruenbaum, Lore ; Bitter, Hans ; Rasmussen, Erik ; Ravindran, Palanikumar ; Swinney, David C ; Birzele, Fabian ; Schmucki, Roland ; Lorenz, Stefan H ; Kopetzki, Erhard ; Carter, Jade ; Triyatni, Miriam ; Thampi, Linta M ; Yang, Junming ; AlDeghaither, Dalal ; Murreddu, Marta G ; Cote, Paul ; Menne, Stephan

PLoS pathogens, 2016-03, Vol.12 (3), p.e1005541-e1005541 [Periódico revisado por pares]

United States: Public Library of Science

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7
Inhibition of pro-inflammatory cytokine production by the dual p38/JNK2 inhibitor BIRB796 correlates with the inhibition of p38 signaling
Inhibition of pro-inflammatory cytokine production by the dual p38/JNK2 inhibitor BIRB796 correlates with the inhibition of p38 signaling
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Inhibition of pro-inflammatory cytokine production by the dual p38/JNK2 inhibitor BIRB796 correlates with the inhibition of p38 signaling

Gruenbaum, Lore M. ; Schwartz, Racheline ; Woska, Joseph R. ; DeLeon, Rodney P. ; Peet, Gregory W. ; Warren, Thomas C. ; Capolino, Alison ; Mara, Lisa ; Morelock, Maurice M. ; Shrutkowski, Anthony ; Jones, Jessi Wildeson ; Pargellis, Christopher A.

Biochemical pharmacology, 2009-02, Vol.77 (3), p.422-432 [Periódico revisado por pares]

Amsterdam: Elsevier Inc

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8
Impaired synaptic plasticity and learning in mice lacking beta-adducin, an actin-regulating protein
Impaired synaptic plasticity and learning in mice lacking beta-adducin, an actin-regulating protein
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Impaired synaptic plasticity and learning in mice lacking beta-adducin, an actin-regulating protein

Rabenstein, Rebecca L ; Addy, Nii A ; Caldarone, Barbara J ; Asaka, Yukiko ; Gruenbaum, Lore M ; Peters, Luanne L ; Gilligan, Diana M ; Fitzsimonds, Reiko M ; Picciotto, Marina R

The Journal of neuroscience, 2005-02, Vol.25 (8), p.2138-2145 [Periódico revisado por pares]

United States: Society for Neuroscience

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9
Phenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization
Phenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization
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Phenocopy--a strategy to qualify chemical compounds during hit-to-lead and/or lead optimization

Baum, Patrick ; Schmid, Ramona ; Ittrich, Carina ; Rust, Werner ; Fundel-Clemens, Katrin ; Siewert, Susanne ; Baur, Martin ; Mara, Lisa ; Gruenbaum, Lore ; Heckel, Armin ; Eils, Roland ; Kontermann, Roland E ; Roth, Gerald J ; Gantner, Florian ; Schnapp, Andreas ; Park, John E ; Weith, Andreas ; Quast, Karsten ; Mennerich, Detlev Falciani, Francesco

PloS one, 2010-12, Vol.5 (12), p.e14272-e14272 [Periódico revisado por pares]

United States: Public Library of Science

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10
Abstract 4126: Inferring target occupancy from fitting nonlinear-PK data with mechanistic PKRO model for Pembrolizumab
Abstract 4126: Inferring target occupancy from fitting nonlinear-PK data with mechanistic PKRO model for Pembrolizumab
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Abstract 4126: Inferring target occupancy from fitting nonlinear-PK data with mechanistic PKRO model for Pembrolizumab

Hua, Fei ; Lin, Lin ; Gruenbaum, Lore ; Millard, Bjorn L. ; Burke, John M. ; Apgar, Joshua F.

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.4126-4126 [Periódico revisado por pares]

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