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1
Targeting Metabolism for Cancer Therapy
Targeting Metabolism for Cancer Therapy
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Targeting Metabolism for Cancer Therapy

Luengo, Alba ; Gui, Dan Y. ; Vander Heiden, Matthew G.

Cell chemical biology, 2017-09, Vol.24 (9), p.1161-1180 [Periódico revisado por pares]

United States: Elsevier Ltd

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2
AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations
AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations
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AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations

Yen, Katharine ; Travins, Jeremy ; Wang, Fang ; David, Muriel D ; Artin, Erin ; Straley, Kimberly ; Padyana, Anil ; Gross, Stefan ; DeLaBarre, Byron ; Tobin, Erica ; Chen, Yue ; Nagaraja, Raj ; Choe, Sung ; Jin, Lei ; Konteatis, Zenon ; Cianchetta, Giovanni ; Saunders, Jeffrey O ; Salituro, Francesco G ; Quivoron, Cyril ; Opolon, Paule ; Bawa, Olivia ; Saada, Véronique ; Paci, Angelo ; Broutin, Sophie ; Bernard, Olivier A ; de Botton, Stéphane ; Marteyn, Benoît S ; Pilichowska, Monika ; Xu, YingXia ; Fang, Cheng ; Jiang, Fan ; Wei, Wentao ; Jin, Shengfang ; Silverman, Lee ; Liu, Wei ; Yang, Hua ; Dang, Lenny ; Dorsch, Marion ; Penard-Lacronique, Virginie ; Biller, Scott A ; Su, Shin-San Michael

Cancer discovery, 2017-05, Vol.7 (5), p.478-493

United States

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3
Biological Role and Therapeutic Potential of IDH Mutations in Cancer
Biological Role and Therapeutic Potential of IDH Mutations in Cancer
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Biological Role and Therapeutic Potential of IDH Mutations in Cancer

Waitkus, Matthew S. ; Diplas, Bill H. ; Yan, Hai

Cancer cell, 2018-08, Vol.34 (2), p.186-195 [Periódico revisado por pares]

United States: Elsevier Inc

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4
Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia
Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia
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Enasidenib in mutant IDH2 relapsed or refractory acute myeloid leukemia

Stein, Eytan M. ; DiNardo, Courtney D. ; Pollyea, Daniel A. ; Fathi, Amir T. ; Roboz, Gail J. ; Altman, Jessica K. ; Stone, Richard M. ; DeAngelo, Daniel J. ; Levine, Ross L. ; Flinn, Ian W. ; Kantarjian, Hagop M. ; Collins, Robert ; Patel, Manish R. ; Frankel, Arthur E. ; Stein, Anthony ; Sekeres, Mikkael A. ; Swords, Ronan T. ; Medeiros, Bruno C. ; Willekens, Christophe ; Vyas, Paresh ; Tosolini, Alessandra ; Xu, Qiang ; Knight, Robert D. ; Yen, Katharine E. ; Agresta, Sam ; de Botton, Stephane ; Tallman, Martin S.

Blood, 2017-08, Vol.130 (6), p.722-731 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study
Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study
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Ivosidenib in IDH1-mutant, chemotherapy-refractory cholangiocarcinoma (ClarIDHy): a multicentre, randomised, double-blind, placebo-controlled, phase 3 study

Abou-Alfa, Ghassan K ; Macarulla, Teresa ; Javle, Milind M ; Kelley, Robin K ; Lubner, Sam J ; Adeva, Jorge ; Cleary, James M ; Catenacci, Daniel V ; Borad, Mitesh J ; Bridgewater, John ; Harris, William P ; Murphy, Adrian G ; Oh, Do-Youn ; Whisenant, Jonathan ; Lowery, Maeve A ; Goyal, Lipika ; Shroff, Rachna T ; El-Khoueiry, Anthony B ; Fan, Bin ; Wu, Bin ; Chamberlain, Christina X ; Jiang, Liewen ; Gliser, Camelia ; Pandya, Shuchi S ; Valle, Juan W ; Zhu, Andrew X

The lancet oncology, 2020-06, Vol.21 (6), p.796-807 [Periódico revisado por pares]

England: Elsevier Ltd

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6
IDH mutations in cancer and progress toward development of targeted therapeutics
IDH mutations in cancer and progress toward development of targeted therapeutics
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IDH mutations in cancer and progress toward development of targeted therapeutics

Dang, L. ; Yen, K. ; Attar, E.C.

Annals of oncology, 2016-04, Vol.27 (4), p.599-608 [Periódico revisado por pares]

England: Elsevier Ltd

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7
Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib
Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib
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Molecular remission and response patterns in patients with mutant-IDH2 acute myeloid leukemia treated with enasidenib

Stein, Eytan M. ; DiNardo, Courtney D. ; Fathi, Amir T. ; Pollyea, Daniel A. ; Stone, Richard M. ; Altman, Jessica K. ; Roboz, Gail J. ; Patel, Manish R. ; Collins, Robert ; Flinn, Ian W. ; Sekeres, Mikkael A. ; Stein, Anthony S. ; Kantarjian, Hagop M. ; Levine, Ross L. ; Vyas, Paresh ; MacBeth, Kyle J. ; Tosolini, Alessandra ; VanOostendorp, Jason ; Xu, Qiang ; Gupta, Ira ; Lila, Thomas ; Risueno, Alberto ; Yen, Katharine E. ; Wu, Bin ; Attar, Eyal C. ; Tallman, Martin S. ; de Botton, Stéphane

Blood, 2019-02, Vol.133 (7), p.676-687 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML
Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML
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Durable Remissions with Ivosidenib in IDH1-Mutated Relapsed or Refractory AML

DiNardo, Courtney D ; Stein, Eytan M ; de Botton, Stéphane ; Roboz, Gail J ; Altman, Jessica K ; Mims, Alice S ; Swords, Ronan ; Collins, Robert H ; Mannis, Gabriel N ; Pollyea, Daniel A ; Donnellan, Will ; Fathi, Amir T ; Pigneux, Arnaud ; Erba, Harry P ; Prince, Gabrielle T ; Stein, Anthony S ; Uy, Geoffrey L ; Foran, James M ; Traer, Elie ; Stuart, Robert K ; Arellano, Martha L ; Slack, James L ; Sekeres, Mikkael A ; Willekens, Christophe ; Choe, Sung ; Wang, Hongfang ; Zhang, Vickie ; Yen, Katharine E ; Kapsalis, Stephanie M ; Yang, Hua ; Dai, David ; Fan, Bin ; Goldwasser, Meredith ; Liu, Hua ; Agresta, Sam ; Wu, Bin ; Attar, Eyal C ; Tallman, Martin S ; Stone, Richard M ; Kantarjian, Hagop M

The New England journal of medicine, 2018-06, Vol.378 (25), p.2386-2398 [Periódico revisado por pares]

United States: Massachusetts Medical Society

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9
Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery
Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery
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Breaking Cryo-EM Resolution Barriers to Facilitate Drug Discovery

Merk, Alan ; Bartesaghi, Alberto ; Banerjee, Soojay ; Falconieri, Veronica ; Rao, Prashant ; Davis, Mindy I. ; Pragani, Rajan ; Boxer, Matthew B. ; Earl, Lesley A. ; Milne, Jacqueline L.S. ; Subramaniam, Sriram

Cell, 2016-06, Vol.165 (7), p.1698-1707 [Periódico revisado por pares]

United States: Elsevier Inc

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10
Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia
Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia
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Enasidenib, an inhibitor of mutant IDH2 proteins, induces durable remissions in older patients with newly diagnosed acute myeloid leukemia

Pollyea, Daniel A ; Tallman, Martin S ; de Botton, Stéphane ; Kantarjian, Hagop M ; Collins, Robert ; Stein, Anthony S ; Frattini, Mark G ; Xu, Qiang ; Tosolini, Alessandra ; See, Wendy L ; MacBeth, Kyle J ; Agresta, Samuel V ; Attar, Eyal C ; DiNardo, Courtney D ; Stein, Eytan M

Leukemia, 2019-11, Vol.33 (11), p.2575-2584 [Periódico revisado por pares]

England: Nature Publishing Group

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