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Discovery and characterization of COVA322, a clinical-stage bispecific TNF/IL-17A inhibitor for the treatment of inflammatory diseases
Discovery and characterization of COVA322, a clinical-stage bispecific TNF/IL-17A inhibitor for the treatment of inflammatory diseases
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Discovery and characterization of COVA322, a clinical-stage bispecific TNF/IL-17A inhibitor for the treatment of inflammatory diseases

Silacci, Michela ; Lembke, Wibke ; Woods, Richard ; Attinger-Toller, Isabella ; Baenziger-Tobler, Nadja ; Batey, Sarah ; Santimaria, Roger ; von der Bey, Ulrike ; Koenig-Friedrich, Susann ; Zha, Wenjuan ; Schlereth, Bernd ; Locher, Mathias ; Bertschinger, Julian ; Grabulovski, Dragan

mAbs, 2016-01, Vol.8 (1), p.141-149 [Periódico revisado por pares]

United States: Taylor & Francis

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2
A Novel, Non-immunogenic Fyn SH3-derived Binding Protein with Tumor Vascular Targeting Properties
A Novel, Non-immunogenic Fyn SH3-derived Binding Protein with Tumor Vascular Targeting Properties
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A Novel, Non-immunogenic Fyn SH3-derived Binding Protein with Tumor Vascular Targeting Properties

Grabulovski, Dragan ; Kaspar, Manuela ; Neri, Dario

The Journal of biological chemistry, 2007-02, Vol.282 (5), p.3196-3204 [Periódico revisado por pares]

United States: Elsevier Inc

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3
Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain
Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain
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Generation, characterization and structural data of chymase binding proteins based on the human Fyn kinase SH3 domain

Schlatter, Daniel ; Brack, Simon ; Banner, David W. ; Batey, Sarah ; Benz, Jörg ; Bertschinger, Julian ; Huber, Walter ; Joseph, Catherine ; Rufer, Arne C. ; van der Klooster, Anita ; Weber, Martin ; Grabulovski, Dragan ; Hennig, Michael

mAbs, 2012-07, Vol.4 (4), p.497-508 [Periódico revisado por pares]

United States: Taylor & Francis

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4
Bispecific CD3/HER2 Targeting FynomAb Induces Redirected T Cell-Mediated Cytolysis with High Potency and Enhanced Tumor Selectivity
Bispecific CD3/HER2 Targeting FynomAb Induces Redirected T Cell-Mediated Cytolysis with High Potency and Enhanced Tumor Selectivity
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Bispecific CD3/HER2 Targeting FynomAb Induces Redirected T Cell-Mediated Cytolysis with High Potency and Enhanced Tumor Selectivity

Wuellner, Ulrich ; Klupsch, Kristina ; Buller, Fabian ; Attinger-Toller, Isabella ; Santimaria, Roger ; Zbinden, Irene ; Henne, Patricia ; Grabulovski, Dragan ; Bertschinger, Julian ; Brack, Simon

Antibodies (Basel), 2015-12, Vol.4 (4), p.426-440 [Periódico revisado por pares]

MDPI AG

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5
Abstract 1842: CD79b targeting ADC with superior pharmacokinetic profile and anti-tumor activity
Abstract 1842: CD79b targeting ADC with superior pharmacokinetic profile and anti-tumor activity
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Abstract 1842: CD79b targeting ADC with superior pharmacokinetic profile and anti-tumor activity

Spycher, Philipp René ; Probst, Philipp ; Bertrand, Romain ; Stark, Ramona ; Santimaria, Roger ; Grabulovski, Dragan ; Attinger-Toller, Isabella

Cancer research (Chicago, Ill.), 2021-07, Vol.81 (13_Supplement), p.1842-1842 [Periódico revisado por pares]

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6
A bispecific antibody that targets IL-6 receptor and IL-17A for the potential therapy of patients with autoimmune and inflammatory diseases
A bispecific antibody that targets IL-6 receptor and IL-17A for the potential therapy of patients with autoimmune and inflammatory diseases
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A bispecific antibody that targets IL-6 receptor and IL-17A for the potential therapy of patients with autoimmune and inflammatory diseases

Lyman, Michael ; Lieuw, Vincent ; Richardson, Robyn ; Timmer, Anjuli ; Stewart, Christine ; Granger, Steve ; Woods, Richard ; Silacci, Michela ; Grabulovski, Dragan ; Newman, Roland

The Journal of biological chemistry, 2018-06, Vol.293 (24), p.9326-9334 [Periódico revisado por pares]

United States: Elsevier Inc

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7
Linker Length Matters, Fynomer-Fc Fusion with an Optimized Linker Displaying Picomolar IL-17A Inhibition Potency
Linker Length Matters, Fynomer-Fc Fusion with an Optimized Linker Displaying Picomolar IL-17A Inhibition Potency
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Linker Length Matters, Fynomer-Fc Fusion with an Optimized Linker Displaying Picomolar IL-17A Inhibition Potency

Silacci, Michela ; Baenziger-Tobler, Nadja ; Lembke, Wibke ; Zha, Wenjuan ; Batey, Sarah ; Bertschinger, Julian ; Grabulovski, Dragan

The Journal of biological chemistry, 2014-05, Vol.289 (20), p.14392-14398 [Periódico revisado por pares]

United States: Elsevier Inc

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8
A CD79b Targeting ADC with Superior Anti-Tumor Activity and Safety Resulting in Significantly Improved Therapeutic Index (TI): Safe and Efficacious CD79b ADC
A CD79b Targeting ADC with Superior Anti-Tumor Activity and Safety Resulting in Significantly Improved Therapeutic Index (TI): Safe and Efficacious CD79b ADC
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A CD79b Targeting ADC with Superior Anti-Tumor Activity and Safety Resulting in Significantly Improved Therapeutic Index (TI): Safe and Efficacious CD79b ADC

Schlereth, Bernd ; Attinger-toller, Isabella ; Probst, Philipp ; Bertrand, Romain ; Stark, Ramona ; Santimaria, Roger ; Renard, Emma ; Fay, Rachael ; Sharman, Jeff P. ; Grabulovski, Dragan ; Spycher, Philipp

Blood, 2022-11, Vol.140 (Supplement 1), p.11568-11569 [Periódico revisado por pares]

Elsevier Inc

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9
Abstract LB-106: Overcoming limitations of current Antibody-Drug Conjugates (ADCs) by a novel linker technology
Abstract LB-106: Overcoming limitations of current Antibody-Drug Conjugates (ADCs) by a novel linker technology
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Abstract LB-106: Overcoming limitations of current Antibody-Drug Conjugates (ADCs) by a novel linker technology

Spycher, Philipp Rene ; Frei, Julia Carina ; Wehrmüller, Jöri Elias ; Attinger-toller, Isabella ; Grabulovski, Dragan ; Hechler, Torsten ; Kulke, Michael ; Pahl, Andreas ; Behe, Martin ; Schibli, Roger

Cancer research (Chicago, Ill.), 2019-07, Vol.79 (13_Supplement), p.LB-106-LB-106 [Periódico revisado por pares]

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10
A bispecific HER2-targeting FynomAb with superior antitumor activity and novel mode of action
A bispecific HER2-targeting FynomAb with superior antitumor activity and novel mode of action
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A bispecific HER2-targeting FynomAb with superior antitumor activity and novel mode of action

Brack, Simon ; Attinger-Toller, Isabella ; Schade, Babette ; Mourlane, Frédéric ; Klupsch, Kristina ; Woods, Richard ; Hachemi, Helen ; von der Bey, Ulrike ; Koenig-Friedrich, Susann ; Bertschinger, Julian ; Grabulovski, Dragan

Molecular cancer therapeutics, 2014-08, Vol.13 (8), p.2030-2039 [Periódico revisado por pares]

United States

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