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Synthesis and biological evaluation of natural-product-inspired, aminoalkyl-substituted 1-benzopyrans as novel antiplasmodial agents
Synthesis and biological evaluation of natural-product-inspired, aminoalkyl-substituted 1-benzopyrans as novel antiplasmodial agents
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Synthesis and biological evaluation of natural-product-inspired, aminoalkyl-substituted 1-benzopyrans as novel antiplasmodial agents

Jan-Frederik Uth Frederik Börgel; Kirstin Lehmkuhl; Dirk Schepmann; Marcel Kaiser; Valquíria Aparecida Polisel Jabor; Maria Cristina Nonato; R. Luise Krauth-Siegel; Thomas J Schmidt; Bernhard Wünsch

Journal of Medicinal Chemistry Washington v. 64, n. 9, p. 6397-6409, 2021

Washington 2021

Localização: FCFRP - Fac. Ciên. Farm. Ribeirão Preto    (pcd 3089967 Acervo Digital )(Acessar)

2
The σ1 Receptor Antagonist S1RA Is a Promising Candidate for the Treatment of Neurogenic Pain
The σ1 Receptor Antagonist S1RA Is a Promising Candidate for the Treatment of Neurogenic Pain
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The σ1 Receptor Antagonist S1RA Is a Promising Candidate for the Treatment of Neurogenic Pain

Wünsch, Bernhard

Journal of medicinal chemistry, 2012-10, Vol.55 (19), p.8209-8210 [Periódico revisado por pares]

American Chemical Society

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3
Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer’s Disease
Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer’s Disease
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Discovery of Potent Cholinesterase Inhibition-Based Multi-Target-Directed Lead Compounds for Synaptoprotection in Alzheimer’s Disease

Turgutalp, Bengisu ; Bhattarai, Prabesh ; Ercetin, Tugba ; Luise, Chiara ; Reis, Rengin ; Gurdal, Enise Ece ; Isaak, Andreas ; Biriken, Derya ; Dinter, Elisabeth ; Sipahi, Hande ; Schepmann, Dirk ; Junker, Anna ; Wünsch, Bernhard ; Sippl, Wolfgang ; Gulcan, Hayrettin Ozan ; Kizil, Caghan ; Yarim, Mine

Journal of medicinal chemistry, 2022-09, Vol.65 (18), p.12292-12318 [Periódico revisado por pares]

United States: American Chemical Society

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4
Molecular mechanism of biased signaling at the kappa opioid receptor
Molecular mechanism of biased signaling at the kappa opioid receptor
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Molecular mechanism of biased signaling at the kappa opioid receptor

El Daibani, Amal ; Paggi, Joseph M ; Kim, Kuglae ; Laloudakis, Yianni D ; Popov, Petr ; Bernhard, Sarah M ; Krumm, Brian E ; Olsen, Reid H J ; Diberto, Jeffrey ; Carroll, F Ivy ; Katritch, Vsevolod ; Wünsch, Bernhard ; Dror, Ron O ; Che, Tao

Nature communications, 2023-03, Vol.14 (1), p.1338-1338, Article 1338 [Periódico revisado por pares]

England: Nature Publishing Group

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5
Development of Novel Quinoxaline-Based κ‑Opioid Receptor Agonists for the Treatment of Neuroinflammation
Development of Novel Quinoxaline-Based κ‑Opioid Receptor Agonists for the Treatment of Neuroinflammation
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Development of Novel Quinoxaline-Based κ‑Opioid Receptor Agonists for the Treatment of Neuroinflammation

Tangherlini, Giovanni ; Kalinin, Dmitrii V ; Schepmann, Dirk ; Che, Tao ; Mykicki, Nadine ; Ständer, Sonja ; Loser, Karin ; Wünsch, Bernhard

Journal of medicinal chemistry, 2019-01, Vol.62 (2), p.893-907 [Periódico revisado por pares]

United States: American Chemical Society

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6
Short and Atom-Economic Enantioselective Synthesis of the σ1‑Receptor Ligands (S)- and (R)‑FluspidineImportant Tools for Positron Emission Tomography Studies
Short and Atom-Economic Enantioselective Synthesis of the σ1‑Receptor Ligands (S)- and (R)‑FluspidineImportant Tools for Positron Emission Tomography Studies
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Short and Atom-Economic Enantioselective Synthesis of the σ1‑Receptor Ligands (S)- and (R)‑FluspidineImportant Tools for Positron Emission Tomography Studies

Bunse, Paul ; Schlepphorst, Christoph ; Glorius, Frank ; Kitamura, Masato ; Wünsch, Bernhard

Journal of organic chemistry, 2019-11, Vol.84 (21), p.13744-13754 [Periódico revisado por pares]

American Chemical Society

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7
Conformationally Restricted σ1 Receptor Antagonists from (−)-Isopulegol
Conformationally Restricted σ1 Receptor Antagonists from (−)-Isopulegol
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Conformationally Restricted σ1 Receptor Antagonists from (−)-Isopulegol

Blicker, Luca ; González-Cano, Rafael ; Laurini, Erik ; Nieto, Francisco R. ; Schmidt, Judith ; Schepmann, Dirk ; Pricl, Sabrina ; Wünsch, Bernhard

Journal of medicinal chemistry, 2023-04, Vol.66 (7), p.4999-5020 [Periódico revisado por pares]

American Chemical Society

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8
Indazole as a Phenol Bioisostere: Structure–Affinity Relationships of GluN2B-Selective NMDA Receptor Antagonists
Indazole as a Phenol Bioisostere: Structure–Affinity Relationships of GluN2B-Selective NMDA Receptor Antagonists
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Indazole as a Phenol Bioisostere: Structure–Affinity Relationships of GluN2B-Selective NMDA Receptor Antagonists

Lüken, Judith ; Goerges, Gunnar ; Ritter, Nadine ; Disse, Paul ; Schreiber, Julian A. ; Schmidt, Judith ; Frehland, Bastian ; Schepmann, Dirk ; Seebohm, Guiscard ; Wünsch, Bernhard

Journal of medicinal chemistry, 2023-08, Vol.66 (16), p.11573-11588 [Periódico revisado por pares]

United States: American Chemical Society

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9
Natural Product Derived Antiprotozoal Agents: Synthesis, Biological Evaluation, and Structure–Activity Relationships of Novel Chromene and Chromane Derivatives
Natural Product Derived Antiprotozoal Agents: Synthesis, Biological Evaluation, and Structure–Activity Relationships of Novel Chromene and Chromane Derivatives
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Natural Product Derived Antiprotozoal Agents: Synthesis, Biological Evaluation, and Structure–Activity Relationships of Novel Chromene and Chromane Derivatives

Harel, Dipak ; Schepmann, Dirk ; Prinz, Helge ; Brun, Reto ; Schmidt, Thomas J ; Wünsch, Bernhard

Journal of medicinal chemistry, 2013-09, Vol.56 (18), p.7442-7448 [Periódico revisado por pares]

United States: American Chemical Society

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10
Synthesis and Structure–Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety
Synthesis and Structure–Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety
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Synthesis and Structure–Affinity Relationships of Spirocyclic Benzopyrans with Exocyclic Amino Moiety

Kronenberg, Elisabeth ; Weber, Frauke ; Brune, Stefanie ; Schepmann, Dirk ; Almansa, Carmen ; Friedland, Kristina ; Laurini, Erik ; Pricl, Sabrina ; Wünsch, Bernhard

Journal of medicinal chemistry, 2019-04, Vol.62 (8), p.4204-4217 [Periódico revisado por pares]

United States: American Chemical Society

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Deste Autor:

  1. Börgel, F
  2. Kaiser, M
  3. Lehmkuhl, K
  4. Schmidt, T
  5. Uth, J

Neste Assunto:

  1. Science & Technology
  2. Life Sciences & Biomedicine
  3. Chemistry
  4. Pharmacology & Pharmacy
  5. Physical Sciences

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

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