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Refinado por: assunto: Basic Medicine remover assunto: Mice remover
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1
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls
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Exome sequencing of 20,791 cases of type 2 diabetes and 24,440 controls

Mercader, Josep M ; Udler, Miriam S ; Wessel, Jennifer ; Teslovich, Tanya M ; Caulkins, Lizz ; Barajas-Olmos, Francisco ; Boerwinkle, Eric ; Chen, Ling ; Contreras-Cubas, Cecilia ; Córdova, Emilio ; Correa, Adolfo ; DeFronzo, Ralph A ; Dolan, Lawrence ; Elliott, Amanda ; Floyd, James S ; Garay-Sevilla, Maria Eugenia ; García-Ortiz, Humberto ; Heard-Costa, Nancy L ; Jørgensen, Marit E ; Kang, Hyun Min ; Kelsey, Megan ; Linneberg, Allan ; Liu, Ching-Ti ; Liu, Jianjun ; Lyssenko, Valeriya ; Marcketta, Anthony ; Martínez-Hernández, Angélica ; Mayer-Davis, Elizabeth ; Morrison, Alanna C ; Ndungu, Anne ; Ng, Maggie C Y ; O'Dushlaine, Colm ; Post, Wendy S ; Vasan, Ramachandran S ; Rayner, N William ; Revilla-Monsalve, Cristina ; Santoro, Nicola ; Schurmann, Claudia ; Soberón, Xavier ; Strom, Tim M ; Thameem, Farook ; Torres, Jason M ; Vujkovic, Marijana ; Witte, Daniel R ; Atzmon, Gil ; Blangero, John ; Bonnycastle, Lori L ; Chan, Edmund ; Cheng, Ching-Yu ; Collins, Francis S ; de Vries, Paul S ; Glaser, Benjamin ; Gonzalez, Ma Elena ; Groop, Leif ; Kooner, Jaspal Singh ; Kwak, Soo Heon ; Laakso, Markku ; Nilsson, Peter ; Spector, Timothy D ; Tai, E Shyong ; Tuomilehto, Jaakko ; Wilson, James G ; Burke, Brian ; Carey, David J ; Frossard, Philippe ; Hwang, Mi Yeong ; Kim, Young Jin ; Kirchner, H Lester ; Lee, Jong-Young ; Lee, Juyoung ; Loos, Ruth J F ; Ma, Ronald C W ; Morris, Andrew D ; Palmer, Colin N A ; Pankow, James ; Rasheed, Asif ; Saleheen, Danish ; Sim, Xueling ; Small, Kerrin S ; Teo, Yik Ying ; Haiman, Christopher ; Hanis, Craig L ; Dewey, Frederick E ; Baras, Aris ; Gieger, Christian ; Meitinger, Thomas ; Lange, Leslie ; Pedersen, Oluf ; Zeitler, Philip ; Dabelea, Dana ; Abecasis, Goncalo ; Cox, Nancy J ; Sladek, Rob ; Meigs, James B ; Rotter, Jerome I ; Altshuler, David ; Burtt, Noël P ; Morris, Andrew P ; Florez, Jose C ; Boehnke, Michael

Nature (London), 2019-06, Vol.570 (7759), p.71-76 [Periódico revisado por pares]

England: Nature Publishing Group

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2
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics
Visualization and analysis of gene expression in tissue sections by spatial transcriptomics
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Visualization and analysis of gene expression in tissue sections by spatial transcriptomics

Ståhl, Patrik L. ; Salmén, Fredrik ; Vickovic, Sanja ; Lundmark, Anna ; Navarro, José Fernández ; Magnusson, Jens ; Giacomello, Stefania ; Asp, Michaela ; Westholm, Jakub O. ; Huss, Mikael ; Mollbrink, Annelie ; Linnarsson, Sten ; Codeluppi, Simone ; Borg, Åke ; Pontén, Fredrik ; Costea, Paul Igor ; Sahlén, Pelin ; Mulder, Jan ; Bergmann, Olaf ; Lundeberg, Joakim ; Frisén, Jonas

Science (American Association for the Advancement of Science), 2016-07, Vol.353 (6294), p.78-82 [Periódico revisado por pares]

United States: American Association for the Advancement of Science

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3
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
Trans-ethnic association study of blood pressure determinants in over 750,000 individuals
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Trans-ethnic association study of blood pressure determinants in over 750,000 individuals

Giri, Ayush ; Hellwege, Jacklyn N ; Keaton, Jacob M ; Park, Jihwan ; Qiu, Chengxiang ; Warren, Helen R ; Torstenson, Eric S ; Kovesdy, Csaba P ; Sun, Yan V ; Wilson, Otis D ; Robinson-Cohen, Cassianne ; Roumie, Christianne L ; Chung, Cecilia P ; Birdwell, Kelly A ; Damrauer, Scott M ; DuVall, Scott L ; Klarin, Derek ; Cho, Kelly ; Wang, Yu ; Evangelou, Evangelos ; Cabrera, Claudia P ; Wain, Louise V ; Shrestha, Rojesh ; Mautz, Brian S ; Akwo, Elvis A ; Sargurupremraj, Muralidharan ; Debette, Stéphanie ; Boehnke, Michael ; Scott, Laura J ; Luan, Jian'an ; Zhao, Jing-Hua ; Willems, Sara M ; Thériault, Sébastien ; Shah, Nabi ; Oldmeadow, Christopher ; Almgren, Peter ; Li-Gao, Ruifang ; Verweij, Niek ; Boutin, Thibaud S ; Mangino, Massimo ; Ntalla, Ioanna ; Feofanova, Elena ; Surendran, Praveen ; Cook, James P ; Karthikeyan, Savita ; Lahrouchi, Najim ; Liu, Chunyu ; Sepúlveda, Nuno ; Richardson, Tom G ; Kraja, Aldi ; Amouyel, Philippe ; Farrall, Martin ; Poulter, Neil R ; Laakso, Markku ; Zeggini, Eleftheria ; Sever, Peter ; Scott, Robert A ; Langenberg, Claudia ; Wareham, Nicholas J ; Conen, David ; Palmer, Colin Neil Alexander ; Attia, John ; Chasman, Daniel I ; Ridker, Paul M ; Melander, Olle ; Mook-Kanamori, Dennis Owen ; Harst, Pim van der ; Cucca, Francesco ; Schlessinger, David ; Hayward, Caroline ; Spector, Tim D ; Jarvelin, Marjo-Riitta ; Hennig, Branwen J ; Timpson, Nicholas J ; Wei, Wei-Qi ; Smith, Joshua C ; Xu, Yaomin ; Matheny, Michael E ; Siew, Edward E ; Lindgren, Cecilia ; Herzig, Karl-Heinz ; Dedoussis, George ; Denny, Joshua C ; Psaty, Bruce M ; Howson, Joanna M M ; Munroe, Patricia B ; Newton-Cheh, Christopher ; Caulfield, Mark J ; Elliott, Paul ; Gaziano, J Michael ; Concato, John ; Wilson, Peter W F ; Tsao, Philip S ; Velez Edwards, Digna R ; Susztak, Katalin ; O'Donnell, Christopher J ; Hung, Adriana M ; Edwards, Todd L

Nature genetics, 2019-01, Vol.51 (1), p.51-62 [Periódico revisado por pares]

United States: Nature Publishing Group

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4
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance
Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance
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Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance

Lotta, Luca A ; Gulati, Pawan ; Day, Felix R ; Payne, Felicity ; Ongen, Halit ; van de Bunt, Martijn ; Gaulton, Kyle J ; Eicher, John D ; Sharp, Stephen J ; Luan, Jian'an ; De Lucia Rolfe, Emanuella ; Stewart, Isobel D ; Wheeler, Eleanor ; Willems, Sara M ; Adams, Claire ; Yaghootkar, Hanieh ; Forouhi, Nita G ; Khaw, Kay-Tee ; Johnson, Andrew D ; Semple, Robert K ; Frayling, Timothy ; Perry, John R B ; Dermitzakis, Emmanouil ; McCarthy, Mark I ; Barroso, Inês ; Wareham, Nicholas J ; Savage, David B ; Langenberg, Claudia ; O'Rahilly, Stephen ; Scott, Robert A

Nature genetics, 2017-01, Vol.49 (1), p.17-26 [Periódico revisado por pares]

United States: Nature Publishing Group

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5
Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing
Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing
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Spatially and functionally distinct subclasses of breast cancer-associated fibroblasts revealed by single cell RNA sequencing

Bartoschek, Michael ; Oskolkov, Nikolay ; Bocci, Matteo ; Lövrot, John ; Larsson, Christer ; Sommarin, Mikael ; Madsen, Chris D ; Lindgren, David ; Pekar, Gyula ; Karlsson, Göran ; Ringnér, Markus ; Bergh, Jonas ; Björklund, Åsa ; Pietras, Kristian

Nature communications, 2018-12, Vol.9 (1), p.5150-13, Article 5150 [Periódico revisado por pares]

England: Nature Publishing Group

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6
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity
Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity
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Sequencing of 640,000 exomes identifies GPR75 variants associated with protection from obesity

Akbari, Parsa ; Gilani, Ankit ; Sosina, Olukayode ; Kosmicki, Jack A ; Khrimian, Lori ; Fang, Yi-Ya ; Persaud, Trikaldarshi ; Garcia, Victor ; Sun, Dylan ; Li, Alexander ; Mbatchou, Joelle ; Locke, Adam E ; Benner, Christian ; Verweij, Niek ; Lin, Nan ; Hossain, Sakib ; Agostinucci, Kevin ; Pascale, Jonathan V ; Dirice, Ercument ; Dunn, Michael ; Kraus, William E ; Shah, Svati H ; Chen, Yii-Der I ; Rotter, Jerome I ; Rader, Daniel J ; Melander, Olle ; Still, Christopher D ; Mirshahi, Tooraj ; Carey, David J ; Berumen-Campos, Jaime ; Kuri-Morales, Pablo ; Alegre-Díaz, Jesus ; Torres, Jason M ; Emberson, Jonathan R ; Collins, Rory ; Balasubramanian, Suganthi ; Hawes, Alicia ; Jones, Marcus ; Zambrowicz, Brian ; Murphy, Andrew J ; Paulding, Charles ; Coppola, Giovanni ; Overton, John D ; Reid, Jeffrey G ; Shuldiner, Alan R ; Cantor, Michael ; Kang, Hyun M ; Abecasis, Goncalo R ; Karalis, Katia ; Economides, Aris N ; Marchini, Jonathan ; Yancopoulos, George D ; Sleeman, Mark W ; Altarejos, Judith ; Della Gatta, Giusy ; Tapia-Conyer, Roberto ; Schwartzman, Michal L ; Baras, Aris ; Ferreira, Manuel A R ; Lotta, Luca A

Science (American Association for the Advancement of Science), 2021-07, Vol.373 (6550) [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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7
Genetic insights into biological mechanisms governing human ovarian ageing
Genetic insights into biological mechanisms governing human ovarian ageing
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Genetic insights into biological mechanisms governing human ovarian ageing

Hussain, Jazib ; Claringbould, Annique ; Bakker, Olivier B ; Walters, Robin G ; Terao, Chikashi ; Onland-Moret, N Charlotte ; Olsen, Kristina W ; Arnold, Alice M ; Bandinelli, Stefania ; Bergmann, Sven ; Bochud, Murielle ; Boerwinkle, Eric ; Bowker, Nicholas ; Broer, Linda ; Buring, Julie E ; Campbell, Archie ; Corre, Tanguy ; Couch, Fergus J ; Cross, Simon S ; Cucca, Francesco ; Smith, George Davey ; de Mutsert, Renée ; Dwek, Miriam ; Eriksson, Mikael ; Esko, Tõnu ; Fasching, Peter A ; Faul, Jessica D ; García-Closas, Montserrat ; Grallert, Harald ; Gudbjartsson, Daniel F ; Guénel, Pascal ; Håkansson, Niclas ; Hayward, Caroline ; Heiss, Gerardo ; Høffding, Miya K ; Hottenga, Jouke J ; Hu, Frank ; Hunter, David ; Kardia, Sharon L R ; Kartsonaki, Christiana ; Karlsson, Robert ; Kraft, Peter ; Kurian, Allison W ; Langenberg, Claudia ; Laven, Joop S E ; Lawlor, Deborah A ; Li, Jingmei ; Lindstrom, Sara ; Lindstrom, Tricia ; Linet, Martha ; Luan, Jian'an ; Mägi, Reedik ; Mangino, Massimo ; Mbarek, Hamdi ; Medland, Sarah E ; Meitinger, Thomas ; Metspalu, Andres ; Newman, Anne ; Nyholt, Dale R ; Olshan, Andrew F ; Olsson, Håkan ; Perjakova, Natalia ; Porcu, Eleonora ; Rahman, Iffat ; Rennert, Hedy S ; Rosendaal, Frits R ; Rossouw, Jacques ; Rudan, Igor ; Rueedi, Rico ; Saloustros, Emmanouil ; Sandler, Dale P ; Schmidt, Marjanka K ; Schraut, Katharina E ; Shekari, Saleh ; Smith, Jennifer A ; Southey, Melissa C ; Spector, Tim D ; Styrkarsdottir, Unnur ; Teumer, Alexander ; Toniolo, Daniela ; Traglia, Michela ; Uitterlinden, André G ; Ulivi, Sheila ; Vachon, Celine M ; Völker, Uwe ; Völzke, Henry ; Wareham, Nicholas J ; Wilcox, Amber N ; van Dijk, Ko Willems ; Wilson, James F ; Wolffenbuttel, Bruce H R ; Wolk, Alicja ; Wood, Andrew R ; Burgess, Stephen ; Daniel, Jeremy A ; Easton, Douglas F ; Namekawa, Satoshi H ; Solc, Petr ; Murabito, Joanne M ; Perry, John R B

Nature (London), 2021-08, Vol.596 (7872), p.393-397 [Periódico revisado por pares]

England: Nature Publishing Group

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8
An integrated expression atlas of miRNAs and their promoters in human and mouse
An integrated expression atlas of miRNAs and their promoters in human and mouse
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An integrated expression atlas of miRNAs and their promoters in human and mouse

de Rie, Derek ; Abugessaisa, Imad ; Alam, Tanvir ; Arner, Erik ; Arner, Peter ; Ashoor, Haitham ; Åström, Gaby ; Babina, Magda ; Bertin, Nicolas ; Burroughs, A Maxwell ; Carlisle, Ailsa J ; Daub, Carsten O ; Detmar, Michael ; Deviatiiarov, Ruslan ; Fort, Alexandre ; Gebhard, Claudia ; Goldowitz, Daniel ; Guhl, Sven ; Ha, Thomas J ; Harshbarger, Jayson ; Hasegawa, Akira ; Hashimoto, Kosuke ; Herlyn, Meenhard ; Heutink, Peter ; Hitchens, Kelly J ; Hon, Chung Chau ; Huang, Edward ; Ishizu, Yuri ; Kai, Chieko ; Kasukawa, Takeya ; Klinken, Peter ; Lassmann, Timo ; Lecellier, Charles-Henri ; Lee, Weonju ; Lizio, Marina ; Makeev, Vsevolod ; Mathelier, Anthony ; Medvedeva, Yulia A ; Mejhert, Niklas ; Mungall, Christopher J ; Noma, Shohei ; Ohshima, Mitsuhiro ; Okada-Hatakeyama, Mariko ; Persson, Helena ; Rizzu, Patrizia ; Roudnicky, Filip ; Sætrom, Pål ; Sato, Hiroki ; Severin, Jessica ; Shin, Jay W ; Swoboda, Rolf K ; Tarui, Hiroshi ; Toyoda, Hiroo ; Vitting-Seerup, Kristoffer ; Winteringham, Louise ; Yamaguchi, Yoko ; Yasuzawa, Kayoko ; Yoneda, Misako ; Yumoto, Noriko ; Zabierowski, Susan ; Zhang, Peter G ; Wells, Christine A ; Summers, Kim M ; Kawaji, Hideya ; Sandelin, Albin ; Rehli, Michael ; Hayashizaki, Yoshihide ; Carninci, Piero ; Forrest, Alistair R R ; de Hoon, Michiel J L

Nature biotechnology, 2017-09, Vol.35 (9), p.872-878 [Periódico revisado por pares]

United States: Nature Publishing Group

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9
The human gut microbiome in early-onset type 1 diabetes from the TEDDY study
The human gut microbiome in early-onset type 1 diabetes from the TEDDY study
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The human gut microbiome in early-onset type 1 diabetes from the TEDDY study

Vatanen, Tommi ; Franzosa, Eric A ; Schwager, Randall ; Tripathi, Surya ; Arthur, Timothy D ; Vehik, Kendra ; Lernmark, Åke ; Hagopian, William A ; Rewers, Marian J ; She, Jin-Xiong ; Toppari, Jorma ; Ziegler, Anette-G ; Akolkar, Beena ; Krischer, Jeffrey P ; Stewart, Christopher J ; Ajami, Nadim J ; Petrosino, Joseph F ; Gevers, Dirk ; Lähdesmäki, Harri ; Vlamakis, Hera ; Huttenhower, Curtis ; Xavier, Ramnik J

Nature (London), 2018-10, Vol.562 (7728), p.589-594 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Consensus guidelines for the use and interpretation of angiogenesis assays
Consensus guidelines for the use and interpretation of angiogenesis assays
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Consensus guidelines for the use and interpretation of angiogenesis assays

Nowak-Sliwinska, Patrycja ; Alitalo, Kari ; Allen, Elizabeth ; Anisimov, Andrey ; Aplin, Alfred C. ; Auerbach, Robert ; Augustin, Hellmut G. ; Bates, David O. ; van Beijnum, Judy R. ; Bender, R. Hugh F. ; Bergers, Gabriele ; Bikfalvi, Andreas ; Bischoff, Joyce ; Böck, Barbara C. ; Brooks, Peter C. ; Bussolino, Federico ; Cakir, Bertan ; Carmeliet, Peter ; Castranova, Daniel ; Cimpean, Anca M. ; Cleaver, Ondine ; Coukos, George ; Davis, George E. ; De Palma, Michele ; Dimberg, Anna ; Dings, Ruud P. M. ; Djonov, Valentin ; Dudley, Andrew C. ; Dufton, Neil P. ; Fendt, Sarah-Maria ; Ferrara, Napoleone ; Fruttiger, Marcus ; Fukumura, Dai ; Ghesquière, Bart ; Gong, Yan ; Griffin, Robert J. ; Harris, Adrian L. ; Hughes, Christopher C. W. ; Hultgren, Nan W. ; Iruela-Arispe, M. Luisa ; Irving, Melita ; Jain, Rakesh K. ; Kalluri, Raghu ; Kalucka, Joanna ; Kerbel, Robert S. ; Kitajewski, Jan ; Klaassen, Ingeborg ; Kleinmann, Hynda K. ; Koolwijk, Pieter ; Kuczynski, Elisabeth ; Kwak, Brenda R. ; Marien, Koen ; Melero-Martin, Juan M. ; Munn, Lance L. ; Nicosia, Roberto F. ; Noel, Agnes ; Nurro, Jussi ; Olsson, Anna-Karin ; Petrova, Tatiana V. ; Pietras, Kristian ; Pili, Roberto ; Pollard, Jeffrey W. ; Post, Mark J. ; Quax, Paul H. A. ; Rabinovich, Gabriel A. ; Raica, Marius ; Randi, Anna M. ; Ribatti, Domenico ; Ruegg, Curzio ; Schlingemann, Reinier O. ; Schulte-Merker, Stefan ; Smith, Lois E. H. ; Song, Jonathan W. ; Stacker, Steven A. ; Stalin, Jimmy ; Stratman, Amber N. ; Van de Velde, Maureen ; van Hinsbergh, Victor W. M. ; Vermeulen, Peter B. ; Waltenberger, Johannes ; Weinstein, Brant M. ; Xin, Hong ; Yetkin-Arik, Bahar ; Yla-Herttuala, Seppo ; Yoder, Mervin C. ; Griffioen, Arjan W.

Angiogenesis (London), 2018-08, Vol.21 (3), p.425-532 [Periódico revisado por pares]

Dordrecht: Springer Netherlands

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