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Action of hexachlorobenzene on tumor growth and metastasis in different experimental models
Action of hexachlorobenzene on tumor growth and metastasis in different experimental models
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Action of hexachlorobenzene on tumor growth and metastasis in different experimental models

Pontillo, Carolina Andrea ; Rojas, Paola ; Chiappini, Florencia ; Sequeira, Gonzalo ; Cocca, Claudia ; Crocci, Máximo ; Colombo, Lucas ; Lanari, Claudia ; Kleiman de Pisarev, Diana ; Randi, Andrea

Toxicology and applied pharmacology, 2013-05, Vol.268 (3), p.331-342 [Periódico revisado por pares]

Amsterdam: Elsevier Inc

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2
Natural isoprenoids inhibit LPS-induced-production of cytokines and nitric oxide in aminobisphosphonate-treated monocytes
Natural isoprenoids inhibit LPS-induced-production of cytokines and nitric oxide in aminobisphosphonate-treated monocytes
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Natural isoprenoids inhibit LPS-induced-production of cytokines and nitric oxide in aminobisphosphonate-treated monocytes

Marcuzzi, Annalisa ; Tommasini, Alberto ; Crovella, Sergio ; Pontillo, Alessandra

International immunopharmacology, 2010-06, Vol.10 (6), p.639-642 [Periódico revisado por pares]

Kidlington: Elsevier B.V

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3
Discovery of Sodium R-(+)-4-{2-[5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (Elagolix), a Potent and Orally Available Nonpeptide Antagonist of the Human Gonadotropin-Releasing Hormone Receptor
Discovery of Sodium R-(+)-4-{2-[5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (Elagolix), a Potent and Orally Available Nonpeptide Antagonist of the Human Gonadotropin-Releasing Hormone Receptor
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Discovery of Sodium R-(+)-4-{2-[5-(2-Fluoro-3-methoxyphenyl)-3-(2-fluoro-6-[trifluoromethyl]benzyl)-4-methyl-2,6-dioxo-3,6-dihydro-2H-pyrimidin-1-yl]-1-phenylethylamino}butyrate (Elagolix), a Potent and Orally Available Nonpeptide Antagonist of the Human Gonadotropin-Releasing Hormone Receptor

Chen, Chen ; Wu, Dongpei ; Guo, Zhiqiang ; Xie, Qiu ; Reinhart, Greg J ; Madan, Ajay ; Wen, Jenny ; Chen, Takung ; Huang, Charles Q ; Chen, Mi ; Chen, Yongsheng ; Tucci, Fabio C ; Rowbottom, Martin ; Pontillo, Joseph ; Zhu, Yun-Fei ; Wade, Warren ; Saunders, John ; Bozigian, Haig ; Struthers, R. Scott

Journal of medicinal chemistry, 2008-12, Vol.51 (23), p.7478-7485 [Periódico revisado por pares]

Columbus, OH: American Chemical Society

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4
Alterations in c-Src/HER1 and estrogen receptor α signaling pathways in mammary gland and tumors of hexachlorobenzene-treated rats
Alterations in c-Src/HER1 and estrogen receptor α signaling pathways in mammary gland and tumors of hexachlorobenzene-treated rats
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Alterations in c-Src/HER1 and estrogen receptor α signaling pathways in mammary gland and tumors of hexachlorobenzene-treated rats

Peña, Delfina ; Pontillo, Carolina ; García, María Alejandra ; Cocca, Claudia ; Alvarez, Laura ; Chiappini, Florencia ; Bourguignon, Nadia ; Frahm, Isabel ; Bergoc, Rosa ; Kleiman de Pisarev, Diana ; Randi, Andrea

Toxicology (Amsterdam), 2012-03, Vol.293 (1-3), p.68-77 [Periódico revisado por pares]

Kidlington: Elsevier B.V

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5
Synthesis of aryl-1,2,4-triazine-3,5-diones as antagonists of the gonadotropin-releasing hormone receptor
Synthesis of aryl-1,2,4-triazine-3,5-diones as antagonists of the gonadotropin-releasing hormone receptor
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Synthesis of aryl-1,2,4-triazine-3,5-diones as antagonists of the gonadotropin-releasing hormone receptor

Pontillo, Joseph ; Guo, Zhiqiang ; Wu, Dongpei ; Struthers, R. Scott ; Chen, Chen

Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (19), p.4363-4366 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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6
Hexachlorobenzene induces deregulation of cellular growth in rat liver
Hexachlorobenzene induces deregulation of cellular growth in rat liver
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Hexachlorobenzene induces deregulation of cellular growth in rat liver

Giribaldi, Laura ; Chiappini, Florencia ; Pontillo, Carolina ; Randi, Andrea S ; Kleiman de Pisarev, Diana L ; Alvarez, Laura

Toxicology (Amsterdam), 2011-10, Vol.289 (1), p.19-27 [Periódico revisado por pares]

Kidlington: Elsevier Ireland Ltd

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7
Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines
Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines
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Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines

Tucci, Fabio C. ; White, Nicole S. ; Markison, Stacy ; Joppa, Margaret ; Tran, Joe A. ; Fleck, Beth A. ; Madan, Ajay ; Dyck, Brian P. ; Parker, Jessica ; Pontillo, Joseph ; Melissa Arellano, L. ; Marinkovic, Dragan ; Jiang, Wanlong ; Chen, Caroline W. ; Gogas, Kathleen R. ; Goodfellow, Val S. ; Saunders, John ; Foster, Alan C. ; Chen, Chen

Bioorganic & medicinal chemistry letters, 2005-10, Vol.15 (19), p.4389-4395 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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8
4-{(2R)-[3-Aminopropionylamido]-3-(2,4-dichlorophenyl)propionyl}-1-{2-[(2-thienyl)ethylaminomethyl]phenyl}piperazine as a Potent and Selective Melanocortin-4 Receptor AntagonistDesign, Synthesis, and Characterization
4-{(2R)-[3-Aminopropionylamido]-3-(2,4-dichlorophenyl)propionyl}-1-{2-[(2-thienyl)ethylaminomethyl]phenyl}piperazine as a Potent and Selective Melanocortin-4 Receptor AntagonistDesign, Synthesis, and Characterization
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4-{(2R)-[3-Aminopropionylamido]-3-(2,4-dichlorophenyl)propionyl}-1-{2-[(2-thienyl)ethylaminomethyl]phenyl}piperazine as a Potent and Selective Melanocortin-4 Receptor AntagonistDesign, Synthesis, and Characterization

Chen ; Pontillo, Joseph ; Fleck, Beth A ; Gao, Yinghong ; Wen, Jenny ; Tran, Joe A ; Tucci, Fabio C ; Marinkovic, Dragan ; Foster, Alan C ; Saunders, John

Journal of medicinal chemistry, 2004-12, Vol.47 (27), p.6821-6830 [Periódico revisado por pares]

Washington, DC: American Chemical Society

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9
A potent and selective nonpeptide antagonist of the melanocortin-4 receptor induces food intake in satiated mice
A potent and selective nonpeptide antagonist of the melanocortin-4 receptor induces food intake in satiated mice
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A potent and selective nonpeptide antagonist of the melanocortin-4 receptor induces food intake in satiated mice

Pontillo, Joseph ; Tran, Joseph A. ; Markison, Stacy ; Joppa, Margaret ; Fleck, Beth A. ; Marinkovic, Dragan ; Arellano, Melissa ; Tucci, Fabio C. ; Lanier, Marion ; Nelson, Jodie ; Saunders, John ; Hoare, Sam R.J. ; Foster, Alan C. ; Chen, Chen

Bioorganic & medicinal chemistry letters, 2005-05, Vol.15 (10), p.2541-2546 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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10
Piperazinebenzylamines as potent and selective antagonists of the human melanocortin-4 receptor
Piperazinebenzylamines as potent and selective antagonists of the human melanocortin-4 receptor
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Piperazinebenzylamines as potent and selective antagonists of the human melanocortin-4 receptor

Pontillo, Joseph ; Tran, Joseph A. ; Fleck, Beth A. ; Marinkovic, Dragan ; Arellano, Melissa ; Tucci, Fabio C. ; Lanier, Marion ; Nelson, Jodie ; Parker, Jessica ; Saunders, John ; Murphy, Brian ; Foster, Alan C. ; Chen, Chen

Bioorganic & medicinal chemistry letters, 2004-11, Vol.14 (22), p.5605-5609 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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