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Refinado por: Nome da Publicação: Bioorganic & Medicinal Chemistry Letters remover assunto: Science & Technology remover
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Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors
Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors
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Structure guided design of a series of selective pyrrolopyrimidinone MARK inhibitors

Katz, Jason D. ; Haidle, Andrew ; Childers, Kaleen K. ; Zabierek, Anna A. ; Jewell, James P. ; Hou, Yongquan ; Altman, Michael D. ; Szewczak, Alexander ; Chen, Dapeng ; Harsch, Andreas ; Hayashi, Mansuo ; Warren, Lee ; Hutton, Michael ; Nuthall, Hugh ; Su, Hua-Poo ; Munshi, Sanjeev ; Stanton, Matt G. ; Davies, Ian W. ; Munoz, Ben ; Northrup, Alan

Bioorganic & medicinal chemistry letters, 2017-01, Vol.27 (1), p.114-120 [Periódico revisado por pares]

England: Elsevier Ltd

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2
MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentation
MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentation
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MARK inhibitors: Declaring a No-Go decision on a chemical series based on extensive DMPK experimentation

Haidle, Andrew M. ; Childers, Kaleen K. ; Zabierek, Anna A. ; Katz, Jason D. ; Jewell, James P. ; Hou, Yongquan ; Altman, Michael D. ; Szewczak, Alexander ; Chen, Dapeng ; Harsch, Andreas ; Hayashi, Mansuo ; Warren, Lee ; Hutton, Michael ; Nuthall, Hugh ; Stanton, Matt G. ; Davies, Ian W. ; Munoz, Ben ; Northrup, Alan

Bioorganic & medicinal chemistry letters, 2017-01, Vol.27 (1), p.109-113 [Periódico revisado por pares]

England: Elsevier Ltd

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3
Thiophene carboxamide inhibitors of JAK2 as potential treatments for myleoproliferative neoplasms
Thiophene carboxamide inhibitors of JAK2 as potential treatments for myleoproliferative neoplasms
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Thiophene carboxamide inhibitors of JAK2 as potential treatments for myleoproliferative neoplasms

Haidle, Andrew M ; Zabierek, Anna A ; Childers, Kaleen K ; Rosenstein, Craig ; Mathur, Anjili ; Altman, Michael D ; Chan, Grace ; Xu, Lin ; Bachman, Eric ; Mo, Jan-Rung ; Bouthillette, Melaney ; Rush, Thomas ; Tempest, Paul ; Marshall, C Gary ; Young, Jonathan R

Bioorganic & medicinal chemistry letters, 2014-04, Vol.24 (8), p.1968-1973 [Periódico revisado por pares]

England

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4
Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation
Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation
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Identification of quinazoline based inhibitors of IRAK4 for the treatment of inflammation

Smith, Graham F. ; Altman, Michael D. ; Andresen, Brian ; Baker, James ; Brubaker, Jason D. ; Chen, Hongmin ; Chen, Yiping ; Childers, Matthew ; Donofrio, Anthony ; Ferguson, Heidi ; Fischer, Christian ; Fischmann, Thierry O. ; Gibeau, Craig ; Hicks, Alexander ; Jin, Sue ; Kattar, Sam ; Kleinschek, Melanie A. ; Leccese, Erica ; Lesburg, Charles ; Li, Chaomin ; Lim, Jongwon ; Liu, Duan ; Maclean, John K.F. ; Mansoor, Faruk ; Moy, Lilly Y. ; Mulrooney, Erin F. ; Necheva, Antoaneta S. ; Presland, Jeremy ; Rakhilina, Larissa ; Yang, Ruojing ; Torres, Luis ; Zhang-Hoover, Jie ; Northrup, Alan

Bioorganic & medicinal chemistry letters, 2017-06, Vol.27 (12), p.2721-2726 [Periódico revisado por pares]

England: Elsevier Ltd

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5
Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites
Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites
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Synthesis of methylphenidate analogues and their binding affinities at dopamine and serotonin transport sites

Davies, Huw M.L. ; Hopper, Darrin W. ; Hansen, Tore ; Liu, Quixu ; Childers, Steven R.

Bioorganic & medicinal chemistry letters, 2004-04, Vol.14 (7), p.1799-1802 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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6
The synthesis and biological evaluation of dopamine transporter inhibiting activity of substituted diphenylmethoxypiperidines
The synthesis and biological evaluation of dopamine transporter inhibiting activity of substituted diphenylmethoxypiperidines
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The synthesis and biological evaluation of dopamine transporter inhibiting activity of substituted diphenylmethoxypiperidines

Lapa, Gennady B. ; Byrd, Gary D. ; Lapa, Alla A. ; Budygin, Evgeny A. ; Childers, Steven R. ; Jones, Sara R. ; Harp, Jill J.

Bioorganic & medicinal chemistry letters, 2005-11, Vol.15 (22), p.4915-4918 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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7
Synthesis and monoamine transporter affinity of 3β-(4-(2-pyrrolyl)phenyl)-8-azabicyclo[3.2.1]octanes and 3β-(5-Indolyl)-8-azabicyclo[3.2.1]octanes
Synthesis and monoamine transporter affinity of 3β-(4-(2-pyrrolyl)phenyl)-8-azabicyclo[3.2.1]octanes and 3β-(5-Indolyl)-8-azabicyclo[3.2.1]octanes
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Synthesis and monoamine transporter affinity of 3β-(4-(2-pyrrolyl)phenyl)-8-azabicyclo[3.2.1]octanes and 3β-(5-Indolyl)-8-azabicyclo[3.2.1]octanes

Davies, Huw M.L ; Ren, Pingda ; Kong, Norman ; Sexton, Tammy ; Childers, Steven R

Bioorganic & medicinal chemistry letters, 2001-02, Vol.11 (4), p.487-489 [Periódico revisado por pares]

Oxford: Elsevier Ltd

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