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The Polygenic and Monogenic Basis of Blood Traits and Diseases
The Polygenic and Monogenic Basis of Blood Traits and Diseases
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The Polygenic and Monogenic Basis of Blood Traits and Diseases

Vuckovic, Dragana ; Bao, Erik L. ; Akbari, Parsa ; Mousas, Abdou ; Jiang, Tao ; Chen, Ming-Huei ; Raffield, Laura M. ; Huffman, Jennifer E. ; Ritchie, Scott C. ; Megy, Karyn ; Ponstingl, Hannes ; Penkett, Christopher J. ; Albers, Patrick K. ; Wigdor, Emilie M. ; Sakaue, Saori ; Moscati, Arden ; Manansala, Regina ; Lo, Ken Sin ; Qian, Huijun ; Akiyama, Masato ; Bartz, Traci M. ; Beswick, Andrew ; Bork-Jensen, Jette ; Bottinger, Erwin P. ; van Rooij, Frank J.A. ; Chitrala, Kumaraswamy N. ; Wilson, Peter W.F. ; Choquet, Hélène ; Danesh, John ; Di Angelantonio, Emanuele ; Dimou, Niki ; Ding, Jingzhong ; Elliott, Paul ; Esko, Tõnu ; Evans, Michele K. ; Felix, Stephan B. ; Floyd, James S. ; Grarup, Niels ; Guo, Michael H. ; Guo, Qi ; Greinacher, Andreas ; Haessler, Jeff ; Howson, Joanna M.M. ; Huang, Wei ; Kacprowski, Tim ; Kähönen, Mika ; Kamatani, Yoichiro ; Kanai, Masahiro ; Karthikeyan, Savita ; Koskeridis, Fotios ; Lange, Leslie A. ; Lehtimäki, Terho ; Linneberg, Allan ; Liu, Yongmei ; Lyytikäinen, Leo-Pekka ; Manichaikul, Ani ; Matsuda, Koichi ; Mohlke, Karen L. ; Mononen, Nina ; Murakami, Yoshinori ; Nikus, Kjell ; Pankratz, Nathan ; Pedersen, Oluf ; Preuss, Michael ; Psaty, Bruce M. ; Rich, Stephen S. ; Rodriguez, Benjamin A.T. ; Rosen, Jonathan D. ; Rotter, Jerome I. ; Spracklen, Cassandra N. ; Surendran, Praveen ; Tang, Hua ; Tardif, Jean-Claude ; Ghanbari, Mohsen ; Völzke, Henry ; Watkins, Nicholas A. ; Cai, Na ; Kundu, Kousik ; Watt, Stephen B. ; Walter, Klaudia ; Zonderman, Alan B. ; Cho, Kelly ; Li, Yun ; Loos, Ruth J.F. ; Knight, Julian C. ; Georges, Michel ; Stegle, Oliver ; Evangelou, Evangelos ; Okada, Yukinori ; Roberts, David J. ; Inouye, Michael ; Johnson, Andrew D. ; Auer, Paul L. ; Astle, William J. ; Reiner, Alexander P. ; Butterworth, Adam S. ; Ouwehand, Willem H. ; Lettre, Guillaume ; Sankaran, Vijay G. ; Soranzo, Nicole

Cell, 2020-09, Vol.182 (5), p.1214-1231.e11 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation
Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation
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Association Between Titin Loss-of-Function Variants and Early-Onset Atrial Fibrillation

Choi, Seung Hoan ; Weng, Lu-Chen ; Roselli, Carolina ; Lin, Honghuang ; Haggerty, Christopher M ; Shoemaker, M. Benjamin ; Barnard, John ; Arking, Dan E ; Chasman, Daniel I ; Albert, Christine M ; Chaffin, Mark ; Tucker, Nathan R ; Smith, Jonathan D ; Gupta, Namrata ; Gabriel, Stacey ; Margolin, Lauren ; Shea, Marisa A ; Shaffer, Christian M ; Yoneda, Zachary T ; Boerwinkle, Eric ; Smith, Nicholas L ; Silverman, Edwin K ; Redline, Susan ; Vasan, Ramachandran S ; Burchard, Esteban G ; Gogarten, Stephanie M ; Laurie, Cecelia ; Blackwell, Thomas W ; Abecasis, Gonçalo ; Carey, David J ; Fornwalt, Brandon K ; Smelser, Diane T ; Baras, Aris ; Dewey, Frederick E ; Jaquish, Cashell E ; Papanicolaou, George J ; Sotoodehnia, Nona ; Van Wagoner, David R ; Psaty, Bruce M ; Kathiresan, Sekar ; Darbar, Dawood ; Alonso, Alvaro ; Heckbert, Susan R ; Chung, Mina K ; Roden, Dan M ; Benjamin, Emelia J ; Murray, Michael F ; Lunetta, Kathryn L ; Lubitz, Steven A ; Ellinor, Patrick T

JAMA : the journal of the American Medical Association, 2018-12, Vol.320 (22), p.2354-2364 [Periódico revisado por pares]

United States: American Medical Association

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3
A meta-analysis of genome-wide association studies identifies multiple longevity genes
A meta-analysis of genome-wide association studies identifies multiple longevity genes
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A meta-analysis of genome-wide association studies identifies multiple longevity genes

Deelen, Joris ; Evans, Daniel S ; Arking, Dan E ; Tesi, Niccolò ; Nygaard, Marianne ; Liu, Xiaomin ; Wojczynski, Mary K ; Biggs, Mary L ; van der Spek, Ashley ; Atzmon, Gil ; Ware, Erin B ; Sarnowski, Chloé ; Smith, Albert V ; Seppälä, Ilkka ; Cordell, Heather J ; Dose, Janina ; Amin, Najaf ; Arnold, Alice M ; Ayers, Kristin L ; Barzilai, Nir ; Becker, Elizabeth J ; Beekman, Marian ; Blanché, Hélène ; Christensen, Kaare ; Christiansen, Lene ; Collerton, Joanna C ; Cubaynes, Sarah ; Cummings, Steven R ; Davies, Karen ; Debrabant, Birgit ; Deleuze, Jean-François ; Duncan, Rachel ; Faul, Jessica D ; Franceschi, Claudio ; Galan, Pilar ; Gudnason, Vilmundur ; Harris, Tamara B ; Huisman, Martijn ; Hurme, Mikko A ; Jagger, Carol ; Jansen, Iris ; Jylhä, Marja ; Kähönen, Mika ; Karasik, David ; Kardia, Sharon L R ; Kingston, Andrew ; Kirkwood, Thomas B L ; Launer, Lenore J ; Lehtimäki, Terho ; Lieb, Wolfgang ; Lyytikäinen, Leo-Pekka ; Martin-Ruiz, Carmen ; Min, Junxia ; Nebel, Almut ; Newman, Anne B ; Nie, Chao ; Nohr, Ellen A ; Orwoll, Eric S ; Perls, Thomas T ; Province, Michael A ; Psaty, Bruce M ; Raitakari, Olli T ; Reinders, Marcel J T ; Robine, Jean-Marie ; Rotter, Jerome I ; Sebastiani, Paola ; Smith, Jennifer ; Sørensen, Thorkild I A ; Taylor, Kent D ; Uitterlinden, André G ; van der Flier, Wiesje ; van der Lee, Sven J ; van Duijn, Cornelia M ; van Heemst, Diana ; Vaupel, James W ; Weir, David ; Ye, Kenny ; Zeng, Yi ; Zheng, Wanlin ; Holstege, Henne ; Kiel, Douglas P ; Lunetta, Kathryn L ; Slagboom, P Eline ; Murabito, Joanne M

Nature communications, 2019-08, Vol.10 (1), p.3669-14, Article 3669 [Periódico revisado por pares]

England: Nature Publishing Group

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4
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism
Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism
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Genomic and transcriptomic association studies identify 16 novel susceptibility loci for venous thromboembolism

Lindström, Sara ; Wang, Lu ; Smith, Erin N. ; Gordon, William ; van Hylckama Vlieg, Astrid ; de Andrade, Mariza ; Brody, Jennifer A. ; Pattee, Jack W. ; Haessler, Jeffrey ; Brumpton, Ben M. ; Chasman, Daniel I. ; Suchon, Pierre ; Chen, Ming-Huei ; Turman, Constance ; Germain, Marine ; Wiggins, Kerri L. ; MacDonald, James ; Braekkan, Sigrid K. ; Armasu, Sebastian M. ; Pankratz, Nathan ; Jackson, Rebecca D. ; Nielsen, Jonas B. ; Giulianini, Franco ; Puurunen, Marja K. ; Ibrahim, Manal ; Heckbert, Susan R. ; Damrauer, Scott M. ; Natarajan, Pradeep ; Klarin, Derek ; de Vries, Paul S. ; Sabater-Lleal, Maria ; Huffman, Jennifer E. ; Bammler, Theo K. ; Frazer, Kelly A. ; McCauley, Bryan M. ; Taylor, Kent ; Pankow, James S. ; Reiner, Alexander P. ; Gabrielsen, Maiken E. ; Deleuze, Jean-François ; O'Donnell, Chris J. ; Kim, Jihye ; McKnight, Barbara ; Kraft, Peter ; Hansen, John-Bjarne ; Rosendaal, Frits R. ; Heit, John A. ; Psaty, Bruce M. ; Tang, Weihong ; Kooperberg, Charles ; Hveem, Kristian ; Ridker, Paul M. ; Morange, Pierre-Emmanuel ; Johnson, Andrew D. ; Kabrhel, Christopher ; Trégouët, David-Alexandre ; Smith, Nicholas L.

Blood, 2019-11, Vol.134 (19), p.1645-1657 [Periódico revisado por pares]

United States: Elsevier Inc

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5
Epigenetic Signatures of Cigarette Smoking
Epigenetic Signatures of Cigarette Smoking
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Epigenetic Signatures of Cigarette Smoking

Joehanes, Roby ; Just, Allan C ; Marioni, Riccardo E ; Pilling, Luke C ; Reynolds, Lindsay M ; Mandaviya, Pooja R ; Guan, Weihua ; Xu, Tao ; Elks, Cathy E ; Aslibekyan, Stella ; Moreno-Macias, Hortensia ; Smith, Jennifer A ; Brody, Jennifer A ; Dhingra, Radhika ; Yousefi, Paul ; Pankow, James S ; Kunze, Sonja ; Shah, Sonia H ; McRae, Allan F ; Lohman, Kurt ; Sha, Jin ; Absher, Devin M ; Ferrucci, Luigi ; Zhao, Wei ; Demerath, Ellen W ; Bressler, Jan ; Grove, Megan L ; Huan, Tianxiao ; Liu, Chunyu ; Mendelson, Michael M ; Yao, Chen ; Kiel, Douglas P ; Peters, Annette ; Wang-Sattler, Rui ; Visscher, Peter M ; Wray, Naomi R ; Starr, John M ; Ding, Jingzhong ; Rodriguez, Carlos J ; Wareham, Nicholas J ; Irvin, Marguerite R ; Zhi, Degui ; Barrdahl, Myrto ; Vineis, Paolo ; Ambatipudi, Srikant ; Uitterlinden, André G ; Hofman, Albert ; Schwartz, Joel ; Colicino, Elena ; Hou, Lifang ; Vokonas, Pantel S ; Hernandez, Dena G ; Singleton, Andrew B ; Bandinelli, Stefania ; Turner, Stephen T ; Ware, Erin B ; Smith, Alicia K ; Klengel, Torsten ; Binder, Elisabeth B ; Psaty, Bruce M ; Taylor, Kent D ; Gharib, Sina A ; Swenson, Brenton R ; Liang, Liming ; DeMeo, Dawn L ; O’Connor, George T ; Herceg, Zdenko ; Ressler, Kerry J ; Conneely, Karen N ; Sotoodehnia, Nona ; Kardia, Sharon L R ; Melzer, David ; Baccarelli, Andrea A ; van Meurs, Joyce B J ; Romieu, Isabelle ; Arnett, Donna K ; Ong, Ken K ; Liu, Yongmei ; Waldenberger, Melanie ; Deary, Ian J ; Fornage, Myriam ; Levy, Daniel ; London, Stephanie J

Circulation. Cardiovascular genetics, 2016-10, Vol.9 (5), p.436-447 [Periódico revisado por pares]

United States: American Heart Association, Inc

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6
DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation
DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation
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DNA Methylation Analysis Identifies Loci for Blood Pressure Regulation

Richard, Melissa A. ; Huan, Tianxiao ; Ligthart, Symen ; Gondalia, Rahul ; Jhun, Min A. ; Brody, Jennifer A. ; Irvin, Marguerite R. ; Montasser, May E. ; Jia, Yucheng ; Syme, Catriona ; Salfati, Elias L. ; Boerwinkle, Eric ; Guan, Weihua ; Mosley, Thomas H. ; Bressler, Jan ; Morrison, Alanna C. ; Liu, Chunyu ; Mendelson, Michael M. ; Uitterlinden, André G. ; van Meurs, Joyce B. ; ’t Hoen, Peter A.C. ; van Meurs, Joyce ; Isaacs, Aaron ; Franke, Lude ; Boomsma, Dorret I. ; Pool, René ; Hottenga, Jouke J. ; van Greevenbroek, Marleen M.J. ; Stehouwer, Coen D.A. ; Wijmenga, Cisca ; Zhernakova, Alexandra ; Slagboom, P. Eline ; Beekman, Marian ; Deelen, Joris ; van Heemst, Diana ; Veldink, Jan H. ; van den Berg, Leonard H. ; van Duijn, Cornelia M. ; Hofman, Albert ; Uitterlinden, André G. ; Jhamai, P. Mila ; Verbiest, Michael ; Suchiman, H. Eka D. ; Verkerk, Marijn ; van der Breggen, Ruud ; van Rooij, Jeroen ; Lakenberg, Nico ; Mei, Hailiang ; van Iterson, Maarten ; van Galen, Michiel ; Bot, Jan ; Nooren, Irene ; Moed, Matthijs ; Vermaat, Martijn ; Zhernakova, Dasha V. ; Luijk, René ; Bonder, Marc Jan ; van Dijk, Freerk ; Arindrarto, Wibowo ; Kielbasa, Szymon M. ; Swertz, Morris A. ; van Zwet, Erik W. ; Franco, Oscar H. ; Zhang, Guosheng ; Li, Yun ; Stewart, James D. ; Bis, Joshua C. ; Psaty, Bruce M. ; Chen, Yii-Der Ida ; Kardia, Sharon L.R. ; Zhao, Wei ; Absher, Devin ; Aslibekyan, Stella ; Starr, John M. ; McRae, Allan F. ; Schwartz, Joel D. ; Vokonas, Pantel S. ; Menni, Cristina ; Spector, Tim D. ; Shuldiner, Alan ; Damcott, Coleen M. ; Rotter, Jerome I. ; Palmas, Walter ; Liu, Yongmei ; Paus, Tomáš ; Horvath, Steve ; O’Connell, Jeffrey R. ; Guo, Xiuqing ; Pausova, Zdenka ; Assimes, Themistocles L. ; Sotoodehnia, Nona ; Smith, Jennifer A. ; Arnett, Donna K. ; Deary, Ian J. ; Baccarelli, Andrea A. ; Bell, Jordana T. ; Whitsel, Eric ; Dehghan, Abbas ; Levy, Daniel ; Fornage, Myriam

American journal of human genetics, 2017-12, Vol.101 (6), p.888-902 [Periódico revisado por pares]

United States: Elsevier Inc

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7
Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism
Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism
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Meta-analysis of 65,734 Individuals Identifies TSPAN15 and SLC44A2 as Two Susceptibility Loci for Venous Thromboembolism

Germain, Marine ; Chasman, Daniel I. ; de Haan, Hugoline ; Tang, Weihong ; Lindström, Sara ; Weng, Lu-Chen ; de Andrade, Mariza ; de Visser, Marieke C.H. ; Wiggins, Kerri L. ; Suchon, Pierre ; Saut, Noémie ; Smadja, David M. ; Le Gal, Grégoire ; van Hylckama Vlieg, Astrid ; Di Narzo, Antonio ; Hao, Ke ; Nelson, Christopher P. ; Rocanin-Arjo, Ares ; Folkersen, Lasse ; Monajemi, Ramin ; Rose, Lynda M. ; Brody, Jennifer A. ; Slagboom, Eline ; Aïssi, Dylan ; Gagnon, France ; Deleuze, Jean-Francois ; Deloukas, Panos ; Tzourio, Christophe ; Dartigues, Jean-Francois ; Berr, Claudine ; Taylor, Kent D. ; Civelek, Mete ; Eriksson, Per ; Psaty, Bruce M. ; Houwing-Duitermaat, Jeanine ; Goodall, Alison H. ; Cambien, François ; Kraft, Peter ; Amouyel, Philippe ; Samani, Nilesh J. ; Basu, Saonli ; Ridker, Paul M. ; Rosendaal, Frits R. ; Kabrhel, Christopher ; Folsom, Aaron R. ; Heit, John ; Reitsma, Pieter H. ; Trégouët, David-Alexandre ; Smith, Nicholas L. ; Morange, Pierre-Emmanuel

American journal of human genetics, 2015-04, Vol.96 (4), p.532-542 [Periódico revisado por pares]

United States: Elsevier Inc

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8
Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain
Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain
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Genome-wide meta-analysis of 158,000 individuals of European ancestry identifies three loci associated with chronic back pain

Suri, Pradeep ; Palmer, Melody R ; Tsepilov, Yakov A ; Freidin, Maxim B ; Boer, Cindy G ; Yau, Michelle S ; Evans, Daniel S ; Gelemanovic, Andrea ; Bartz, Traci M ; Nethander, Maria ; Arbeeva, Liubov ; Karssen, Lennart ; Neogi, Tuhina ; Campbell, Archie ; Mellstrom, Dan ; Ohlsson, Claes ; Marshall, Lynn M ; Orwoll, Eric ; Uitterlinden, Andre ; Rotter, Jerome I ; Lauc, Gordan ; Psaty, Bruce M ; Karlsson, Magnus K ; Lane, Nancy E ; Jarvik, Gail P ; Polasek, Ozren ; Hochberg, Marc ; Jordan, Joanne M ; Van Meurs, Joyce B J ; Jackson, Rebecca ; Nielson, Carrie M ; Mitchell, Braxton D ; Smith, Blair H ; Hayward, Caroline ; Smith, Nicholas L ; Aulchenko, Yurii S ; Williams, Frances M K Loos, Ruth J. F.

PLoS genetics, 2018-09, Vol.14 (9), p.e1007601-e1007601 [Periódico revisado por pares]

United States: Public Library of Science

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9
Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis
Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis
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Low-Frequency Synonymous Coding Variation in CYP2R1 Has Large Effects on Vitamin D Levels and Risk of Multiple Sclerosis

Manousaki, Despoina ; Dudding, Tom ; Haworth, Simon ; Hsu, Yi-Hsiang ; Liu, Ching-Ti ; Medina-Gómez, Carolina ; Voortman, Trudy ; van der Velde, Nathalie ; Melhus, Håkan ; Robinson-Cohen, Cassianne ; Cousminer, Diana L. ; Nethander, Maria ; Vandenput, Liesbeth ; Noordam, Raymond ; Forgetta, Vincenzo ; Greenwood, Celia M.T. ; Biggs, Mary L. ; Psaty, Bruce M. ; Rotter, Jerome I. ; Zemel, Babette S. ; Mitchell, Jonathan A. ; Taylor, Bruce ; Lorentzon, Mattias ; Karlsson, Magnus ; Jaddoe, Vincent V.W. ; Tiemeier, Henning ; Campos-Obando, Natalia ; Franco, Oscar H. ; Utterlinden, Andre G. ; Broer, Linda ; van Schoor, Natasja M. ; Ham, Annelies C. ; Ikram, M. Arfan ; Karasik, David ; de Mutsert, Renée ; Rosendaal, Frits R. ; den Heijer, Martin ; Wang, Thomas J. ; Lind, Lars ; Orwoll, Eric S. ; Mook-Kanamori, Dennis O. ; Michaëlsson, Karl ; Kestenbaum, Bryan ; Ohlsson, Claes ; Mellström, Dan ; de Groot, Lisette C.P.G.M. ; Grant, Struan F.A. ; Kiel, Douglas P. ; Zillikens, M. Carola ; Rivadeneira, Fernando ; Sawcer, Stephen ; Timpson, Nicholas J. ; Richards, J. Brent

American journal of human genetics, 2017-08, Vol.101 (2), p.227-238 [Periódico revisado por pares]

United States: Elsevier Inc

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10
Genome-wide association study of blood pressure and hypertension
Genome-wide association study of blood pressure and hypertension
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Genome-wide association study of blood pressure and hypertension

Hwang, Shih-Jen ; Vasan, Ramachandran S ; O'Donnell, Christopher J ; Levy, Daniel ; Mattace-Raso, Francesco U S ; Morrison, Alanna C ; Scharpf, Robert B ; Psaty, Bruce M ; Rice, Kenneth ; Harris, Tamara B ; Ganesh, Santhi K ; Glazer, Nicole L ; Aspelund, Thor ; Larson, Martin G ; Witteman, Jacqueline C M ; Gudnason, Vilmundur ; van Duijn, Cornelia M ; Rivadeneira, Fernando ; Boerwinkle, Eric ; Mitchell, Gary F ; Heiss, Gerardo ; Taylor, Kent ; Chakravarti, Aravinda ; Ehret, Georg B ; Dehghan, Abbas ; Johnson, Andrew D ; Lumley, Thomas ; Eiriksdottir, Gudny ; Köttgen, Anna ; Guo, Xiuqing ; Fox, Caroline S ; Sijbrands, Eric J G ; Bis, Joshua ; Hofman, Albert ; Verwoert, Germaine C ; Uitterlinden, André G ; Launer, Lenore J ; Benjamin, Emelia J ; Aulchenko, Yurii ; Arking, Dan E ; Coresh, Josef ; Rotter, Jerome I ; Wang, Thomas J ; Smith, Albert V

Nature genetics, 2009-06, Vol.41 (6), p.677-687 [Periódico revisado por pares]

New York, NY: Nature Publishing Group

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