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Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer
Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer
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Macrophage-Released Pyrimidines Inhibit Gemcitabine Therapy in Pancreatic Cancer

Halbrook, Christopher J. ; Pontious, Corbin ; Kovalenko, Ilya ; Lapienyte, Laura ; Dreyer, Stephan ; Lee, Ho-Joon ; Thurston, Galloway ; Zhang, Yaqing ; Lazarus, Jenny ; Sajjakulnukit, Peter ; Hong, Hanna S. ; Kremer, Daniel M. ; Nelson, Barbara S. ; Kemp, Samantha ; Zhang, Li ; Chang, David ; Biankin, Andrew ; Shi, Jiaqi ; Frankel, Timothy L. ; Crawford, Howard C. ; Morton, Jennifer P. ; Pasca di Magliano, Marina ; Lyssiotis, Costas A.

Cell metabolism, 2019-06, Vol.29 (6), p.1390-1399.e6 [Periódico revisado por pares]

United States: Elsevier Inc

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2
Novel Pyrimidines as Antitubercular Agents
Novel Pyrimidines as Antitubercular Agents
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Novel Pyrimidines as Antitubercular Agents

Inoyama, Daigo ; Paget, Steven D ; Russo, Riccardo ; Kandasamy, Srinivasan ; Kumar, Pradeep ; Singleton, Eric ; Occi, James ; Tuckman, Margareta ; Zimmerman, Matthew D ; Ho, Hsin Pin ; Perryman, Alexander L ; Dartois, Véronique ; Connell, Nancy ; Freundlich, Joel S

Antimicrobial agents and chemotherapy, 2018-03, Vol.62 (3) [Periódico revisado por pares]

United States: American Society for Microbiology

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3
EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors
EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors
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EGFR Mutations and Resistance to Irreversible Pyrimidine-Based EGFR Inhibitors

Ercan, Dalia ; Choi, Hwan Geun ; Yun, Cai-Hong ; Capelletti, Marzia ; Xie, Ting ; Eck, Michael J ; Gray, Nathanael S ; Jänne, Pasi A

Clinical cancer research, 2015-09, Vol.21 (17), p.3913-3923 [Periódico revisado por pares]

United States

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4
Synthesis and antitumor activity of new sulfonamide derivatives of thiadiazolo[3,2- a]pyrimidines
Synthesis and antitumor activity of new sulfonamide derivatives of thiadiazolo[3,2- a]pyrimidines
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Synthesis and antitumor activity of new sulfonamide derivatives of thiadiazolo[3,2- a]pyrimidines

El-Sayed, Nadia S. ; El-Bendary, Eman R. ; El-Ashry, Saadia M. ; El-Kerdawy, Mohammed M.

European journal of medicinal chemistry, 2011-09, Vol.46 (9), p.3714-3720 [Periódico revisado por pares]

Kidlington: Elsevier Masson SAS

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5
Pyrido [2, 3‐d]pyrimidines and Pyrimido[5′, 4′:5, 6]pyrido[2, 3‐d]pyrimidines as New Antiviral Agents: Synthesis and Biological Activity
Pyrido [2, 3‐d]pyrimidines and Pyrimido[5′, 4′:5, 6]pyrido[2, 3‐d]pyrimidines as New Antiviral Agents: Synthesis and Biological Activity
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Pyrido [2, 3‐d]pyrimidines and Pyrimido[5′, 4′:5, 6]pyrido[2, 3‐d]pyrimidines as New Antiviral Agents: Synthesis and Biological Activity

Nasr, Magda N. ; Gineinah, Magdy M.

Archiv der Pharmazie (Weinheim), 2002-06, Vol.335 (6), p.289-295 [Periódico revisado por pares]

Weinheim: WILEY‐VCH Verlag

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6
Bis(arylvinyl)pyrazines, -pyrimidines, and -pyridazines As Imaging Agents for Tau Fibrils and β‑Amyloid Plaques in Alzheimer’s Disease Models
Bis(arylvinyl)pyrazines, -pyrimidines, and -pyridazines As Imaging Agents for Tau Fibrils and β‑Amyloid Plaques in Alzheimer’s Disease Models
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Bis(arylvinyl)pyrazines, -pyrimidines, and -pyridazines As Imaging Agents for Tau Fibrils and β‑Amyloid Plaques in Alzheimer’s Disease Models

Boländer, Alexander ; Kieser, Daniel ; Voss, Constantin ; Bauer, Silvia ; Schön, Christian ; Burgold, Steffen ; Bittner, Tobias ; Hölzer, Jana ; Heyny-von Haußen, Roland ; Mall, Gerhard ; Goetschy, Valérie ; Czech, Christian ; Knust, Henner ; Berger, Robert ; Herms, Jochen ; Hilger, Ingrid ; Schmidt, Boris

Journal of medicinal chemistry, 2012-11, Vol.55 (21), p.9170-9180 [Periódico revisado por pares]

United States: American Chemical Society

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7
Evaluation of the Structure–Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5‑a]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies
Evaluation of the Structure–Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5‑a]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies
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Evaluation of the Structure–Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5‑a]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies

Oukoloff, Killian ; Nzou, Goodwell ; Varricchio, Carmine ; Lucero, Bobby ; Alle, Thibault ; Kovalevich, Jane ; Monti, Ludovica ; Cornec, Anne-Sophie ; Yao, Yuemang ; James, Michael J ; Trojanowski, John Q ; Lee, Virginia M.-Y ; Smith, Amos B ; Brancale, Andrea ; Brunden, Kurt R ; Ballatore, Carlo

Journal of medicinal chemistry, 2021-01, Vol.64 (2), p.1073-1102 [Periódico revisado por pares]

United States: American Chemical Society

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8
Optimization of 4,6-Disubstituted Pyrido[3,2‑d]pyrimidines as Dual MNK/PIM Inhibitors to Inhibit Leukemia Cell Growth
Optimization of 4,6-Disubstituted Pyrido[3,2‑d]pyrimidines as Dual MNK/PIM Inhibitors to Inhibit Leukemia Cell Growth
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Optimization of 4,6-Disubstituted Pyrido[3,2‑d]pyrimidines as Dual MNK/PIM Inhibitors to Inhibit Leukemia Cell Growth

Han, Yu ; Zhang, Huimin ; Wang, Shuxiang ; Li, Bo ; Xing, Kun ; Shi, Yuntao ; Cao, Hongxue ; Zhang, Jian ; Tong, Tong ; Zang, Jie ; Guan, Lihong ; Gao, Xiaoxiao ; Wang, Yuetong ; Liu, Dan ; Huang, Min ; Jing, Yongkui ; Zhao, Linxiang

Journal of medicinal chemistry, 2021-09, Vol.64 (18), p.13719-13735 [Periódico revisado por pares]

United States: American Chemical Society

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9
Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis
Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis
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Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis

Rabinovich, Shiran ; Adler, Lital ; Yizhak, Keren ; Sarver, Alona ; Silberman, Alon ; Agron, Shani ; Stettner, Noa ; Sun, Qin ; Brandis, Alexander ; Helbling, Daniel ; Korman, Stanley ; Itzkovitz, Shalev ; Dimmock, David ; Ulitsky, Igor ; Nagamani, Sandesh Cs ; Ruppin, Eytan ; Erez, Ayelet

Nature (London), 2015-11, Vol.527 (7578), p.379-383 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Novel Tetrahydropyrido[4,3‑d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90
Novel Tetrahydropyrido[4,3‑d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90
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Novel Tetrahydropyrido[4,3‑d]pyrimidines as Potent Inhibitors of Chaperone Heat Shock Protein 90

Jiang, Fen ; Wang, Hui-Jie ; Jin, Yu-Hui ; Zhang, Qiong ; Wang, Zhi-Hui ; Jia, Jian-Min ; Liu, Fang ; Wang, Lei ; Bao, Qi-Chao ; Li, Dong-Dong ; You, Qi-Dong ; Xu, Xiao-Li

Journal of medicinal chemistry, 2016-12, Vol.59 (23), p.10498-10519 [Periódico revisado por pares]

United States: American Chemical Society

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