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Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals
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Gene discovery and polygenic prediction from a genome-wide association study of educational attainment in 1.1 million individuals

Lee, James J ; Wedow, Robbee ; Okbay, Aysu ; Kong, Edward ; Maghzian, Omeed ; Zacher, Meghan ; Nguyen-Viet, Tuan Anh ; Bowers, Peter ; Sidorenko, Julia ; Karlsson Linnér, Richard ; Fontana, Mark Alan ; Kundu, Tushar ; Lee, Chanwook ; Li, Hui ; Li, Ruoxi ; Royer, Rebecca ; Timshel, Pascal N ; Walters, Raymond K ; Willoughby, Emily A ; Yengo, Loïc ; Alver, Maris ; Bao, Yanchun ; Clark, David W ; Day, Felix R ; Furlotte, Nicholas A ; Joshi, Peter K ; Kemper, Kathryn E ; Kleinman, Aaron ; Langenberg, Claudia ; Mägi, Reedik ; Trampush, Joey W ; Verma, Shefali Setia ; Wu, Yang ; Lam, Max ; Zhao, Jing Hua ; Zheng, Zhili ; Boardman, Jason D ; Campbell, Harry ; Freese, Jeremy ; Harris, Kathleen Mullan ; Hayward, Caroline ; Herd, Pamela ; Kumari, Meena ; Lencz, Todd ; Luan, Jian'an ; Malhotra, Anil K ; Metspalu, Andres ; Milani, Lili ; Ong, Ken K ; Perry, John R B ; Porteous, David J ; Ritchie, Marylyn D ; Smart, Melissa C ; Smith, Blair H ; Tung, Joyce Y ; Wareham, Nicholas J ; Wilson, James F ; Beauchamp, Jonathan P ; Conley, Dalton C ; Esko, Tõnu ; Lehrer, Steven F ; Magnusson, Patrik K E ; Oskarsson, Sven ; Pers, Tune H ; Robinson, Matthew R ; Thom, Kevin ; Watson, Chelsea ; Chabris, Christopher F ; Meyer, Michelle N ; Laibson, David I ; Yang, Jian ; Johannesson, Magnus ; Koellinger, Philipp D ; Turley, Patrick ; Visscher, Peter M ; Benjamin, Daniel J ; Cesarini, David

Nature genetics, 2018-08, Vol.50 (8), p.1112-1121 [Periódico revisado por pares]

United States: Nature Publishing Group

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2
An atlas of genetic influences on osteoporosis in humans and mice
An atlas of genetic influences on osteoporosis in humans and mice
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An atlas of genetic influences on osteoporosis in humans and mice

Morris, John A ; Kemp, John P ; Youlten, Scott E ; Laurent, Laetitia ; Logan, John G ; Chai, Ryan C ; Vulpescu, Nicholas A ; Forgetta, Vincenzo ; Kleinman, Aaron ; Mohanty, Sindhu T ; Sergio, C Marcelo ; Quinn, Julian ; Nguyen-Yamamoto, Loan ; Luco, Aimee-Lee ; Vijay, Jinchu ; Simon, Marie-Michelle ; Pramatarova, Albena ; Medina-Gomez, Carolina ; Trajanoska, Katerina ; Ghirardello, Elena J ; Butterfield, Natalie C ; Curry, Katharine F ; Leitch, Victoria D ; Sparkes, Penny C ; Adoum, Anne-Tounsia ; Mannan, Naila S ; Komla-Ebri, Davide S K ; Pollard, Andrea S ; Dewhurst, Hannah F ; Hassall, Thomas A D ; Beltejar, Michael-John G ; Adams, Douglas J ; Vaillancourt, Suzanne M ; Kaptoge, Stephen ; Baldock, Paul ; Cooper, Cyrus ; Reeve, Jonathan ; Ntzani, Evangelia E ; Evangelou, Evangelos ; Ohlsson, Claes ; Karasik, David ; Rivadeneira, Fernando ; Kiel, Douglas P ; Tobias, Jonathan H ; Gregson, Celia L ; Harvey, Nicholas C ; Grundberg, Elin ; Goltzman, David ; Adams, David J ; Lelliott, Christopher J ; Hinds, David A ; Ackert-Bicknell, Cheryl L ; Hsu, Yi-Hsiang ; Maurano, Matthew T ; Croucher, Peter I ; Williams, Graham R ; Bassett, J H Duncan ; Evans, David M ; Richards, J Brent

Nature genetics, 2019-02, Vol.51 (2), p.258-266 [Periódico revisado por pares]

United States: Nature Publishing Group

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3
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences
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Genome-wide association analyses of risk tolerance and risky behaviors in over 1 million individuals identify hundreds of loci and shared genetic influences

Karlsson Linnér, Richard ; Biroli, Pietro ; Kong, Edward ; Meddens, S Fleur W ; Wedow, Robbee ; Fontana, Mark Alan ; Lebreton, Maël ; Tino, Stephen P ; Abdellaoui, Abdel ; Hammerschlag, Anke R ; Nivard, Michel G ; Okbay, Aysu ; Rietveld, Cornelius A ; Timshel, Pascal N ; Trzaskowski, Maciej ; Vlaming, Ronald de ; Zünd, Christian L ; Bao, Yanchun ; Buzdugan, Laura ; Caplin, Ann H ; Chen, Chia-Yen ; Eibich, Peter ; Fontanillas, Pierre ; Gonzalez, Juan R ; Joshi, Peter K ; Karhunen, Ville ; Kleinman, Aaron ; Levin, Remy Z ; Lill, Christina M ; Meddens, Gerardus A ; Muntané, Gerard ; Sanchez-Roige, Sandra ; Rooij, Frank J van ; Taskesen, Erdogan ; Wu, Yang ; Zhang, Futao ; Auton, Adam ; Boardman, Jason D ; Clark, David W ; Conlin, Andrew ; Dolan, Conor C ; Fischbacher, Urs ; Groenen, Patrick J F ; Harris, Kathleen Mullan ; Hasler, Gregor ; Hofman, Albert ; Ikram, Mohammad A ; Jain, Sonia ; Karlsson, Robert ; Kessler, Ronald C ; Kooyman, Maarten ; MacKillop, James ; Männikkö, Minna ; Morcillo-Suarez, Carlos ; McQueen, Matthew B ; Schmidt, Klaus M ; Smart, Melissa C ; Sutter, Matthias ; Thurik, A Roy ; Uitterlinden, André G ; White, Jon ; Wit, Harriet de ; Yang, Jian ; Bertram, Lars ; Boomsma, Dorret I ; Esko, Tõnu ; Fehr, Ernst ; Hinds, David A ; Johannesson, Magnus ; Kumari, Meena ; Laibson, David ; Magnusson, Patrik K E ; Meyer, Michelle N ; Navarro, Arcadi ; Palmer, Abraham A ; Pers, Tune H ; Posthuma, Danielle ; Schunk, Daniel ; Stein, Murray B ; Svento, Rauli ; Tiemeier, Henning ; Timmers, Paul R H J ; Turley, Patrick ; Ursano, Robert J ; Wagner, Gert G ; Wilson, James F ; Gratten, Jacob ; Lee, James J ; Cesarini, David ; Benjamin, Daniel J ; Koellinger, Philipp D ; Beauchamp, Jonathan P

Nature genetics, 2019-02, Vol.51 (2), p.245-257 [Periódico revisado por pares]

United States: Nature Publishing Group

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4
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation
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Multi-ancestry genetic study of type 2 diabetes highlights the power of diverse populations for discovery and translation

Mahajan, Anubha ; Petty, Lauren E ; Chiou, Joshua ; Miguel-Escalada, Irene ; Nakatochi, Masahiro ; Huerta-Chagoya, Alicia ; Bielak, Lawrence F ; Hai, Yang ; Kals, Mart ; Grarup, Niels ; Wuttke, Matthias ; Nousome, Darryl ; Long, Jirong ; Ahmad, Meraj ; Jensen, Richard A ; An, Ping ; Cade, Brian E ; Abaitua, Fernando ; Akiyama, Masato ; Bertoni, Alain ; Bian, Zheng ; Brummett, Chad M ; Chee, Miao-Li ; Das, Swapan K ; Du, Shufa ; Duan, Qing ; Eckardt, Kai-Uwe ; Fischer, Krista ; Floyd, James S ; Genter, Pauline ; González-Villalpando, Maria Elena ; Gordon-Larsen, Penny ; Gorkin, David ; Herder, Christian ; Hung, Yi-Jen ; Hwu, Chii-Min ; Ikram, Mohammad Arfan ; Ingelsson, Martin ; Islam, Md Tariqul ; Isono, Masato ; Kamatani, Yoichiro ; Katsuya, Tomohiro ; Khor, Chiea-Chuen ; Kohara, Katsuhiko ; Kriebel, Jennifer ; Kuusisto, Johanna ; Läll, Kristi ; Leong, Aaron ; Luan, Jian'an ; Lv, Jun ; Lyssenko, Valeriya ; Meitinger, Thomas ; Morris, Andrew D ; Nadkarni, Girish N ; Nayak, Uma ; Ntalla, Ioanna ; Peters, Annette ; Preissl, Sebastian ; Rasmussen-Torvik, Laura J ; Roden, Michael ; Sabanayagam, Charumathi ; Schönherr, Sebastian ; Shahriar, Mohammad ; Shi, Jinxiu ; Stančáková, Alena ; Strauch, Konstantin ; Thorleifsson, Gudmar ; Thorsteinsdottir, Unnur ; Tsai, Fuu-Jen ; Tusie-Luna, Teresa ; Udler, Miriam S ; Valladares-Salgado, Adan ; Yajnik, Chittaranjan S ; Yoon, Kyungheon ; Igase, Michiya ; Hanis, Craig L ; Ingelsson, Erik ; Zeggini, Eleftheria ; Rich, Stephen S ; Kooperberg, Charles ; Engert, James C ; Wilson, James G ; Kardia, Sharon L R ; Groop, Leif ; Bharadwaj, Dwaipayan ; Sale, Michèle M ; Cruz, Miguel ; Tai, E-Shyong ; Kato, Norihiro ; Laakso, Markku ; Köttgen, Anna ; Loos, Ruth J F ; Saleheen, Danish ; Hansen, Torben ; Kadowaki, Takashi ; Walters, Robin G ; Stefansson, Kari ; Meigs, James B ; Gloyn, Anna L ; Chambers, John C

Nature genetics, 2022-05, Vol.54 (5), p.560-572 [Periódico revisado por pares]

United States: Nature Publishing Group

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5
Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk
Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk
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Modified penetrance of coding variants by cis-regulatory variation contributes to disease risk

Castel, Stephane E ; Cervera, Alejandra ; Mohammadi, Pejman ; Aguet, François ; Reverter, Ferran ; Wolman, Aaron ; Guigo, Roderic ; Iossifov, Ivan ; Vasileva, Ana ; Lappalainen, Tuuli

Nature genetics, 2018-09, Vol.50 (9), p.1327-1334 [Periódico revisado por pares]

United States: Nature Publishing Group

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6
Signatures of negative selection in the genetic architecture of human complex traits
Signatures of negative selection in the genetic architecture of human complex traits
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Signatures of negative selection in the genetic architecture of human complex traits

Zeng, Jian ; de Vlaming, Ronald ; Wu, Yang ; Robinson, Matthew R ; Lloyd-Jones, Luke R ; Yengo, Loic ; Yap, Chloe X ; Xue, Angli ; Sidorenko, Julia ; McRae, Allan F ; Powell, Joseph E ; Montgomery, Grant W ; Metspalu, Andres ; Esko, Tonu ; Gibson, Greg ; Wray, Naomi R ; Visscher, Peter M ; Yang, Jian

Nature genetics, 2018-05, Vol.50 (5), p.746-753 [Periódico revisado por pares]

United States: Nature Publishing Group

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7
Fine-mapping from summary data with the "Sum of Single Effects" model
Fine-mapping from summary data with the "Sum of Single Effects" model
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Fine-mapping from summary data with the "Sum of Single Effects" model

Zou, Yuxin ; Carbonetto, Peter ; Wang, Gao ; Stephens, Matthew Epstein, Michael P.

PLoS genetics, 2022-07, Vol.18 (7), p.e1010299-e1010299 [Periódico revisado por pares]

United States: Public Library of Science

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8
Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits
Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits
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Comparison of methods that use whole genome data to estimate the heritability and genetic architecture of complex traits

Evans, Luke M ; Tahmasbi, Rasool ; Vrieze, Scott I ; Abecasis, Gonçalo R ; Das, Sayantan ; Gazal, Steven ; Bjelland, Douglas W ; de Candia, Teresa R ; Goddard, Michael E ; Neale, Benjamin M ; Yang, Jian ; Visscher, Peter M ; Keller, Matthew C

Nature genetics, 2018-05, Vol.50 (5), p.737-745 [Periódico revisado por pares]

United States: Nature Publishing Group

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9
CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data
CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data
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CHiCAGO: robust detection of DNA looping interactions in Capture Hi-C data

Cairns, Jonathan ; Freire-Pritchett, Paula ; Wingett, Steven W ; Várnai, Csilla ; Dimond, Andrew ; Plagnol, Vincent ; Zerbino, Daniel ; Schoenfelder, Stefan ; Javierre, Biola-Maria ; Osborne, Cameron ; Fraser, Peter ; Spivakov, Mikhail

Genome Biology, 2016-06, Vol.17 (1), p.127-127, Article 127 [Periódico revisado por pares]

England: BioMed Central Ltd

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10
High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction
High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction
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High density methylation QTL analysis in human blood via next-generation sequencing of the methylated genomic DNA fraction

McClay, Joseph L ; Shabalin, Andrey A ; Dozmorov, Mikhail G ; Adkins, Daniel E ; Kumar, Gaurav ; Nerella, Srilaxmi ; Clark, Shaunna L ; Bergen, Sarah E ; Hultman, Christina M ; Magnusson, Patrik K E ; Sullivan, Patrick F ; Aberg, Karolina A ; van den Oord, Edwin J C G

Genome Biology, 2015-12, Vol.16 (1), p.291-291, Article 291 [Periódico revisado por pares]

England: BioMed Central Ltd

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