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The MR-Base platform supports systematic causal inference across the human phenome
The MR-Base platform supports systematic causal inference across the human phenome
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The MR-Base platform supports systematic causal inference across the human phenome

Hemani, Gibran ; Zheng, Jie ; Elsworth, Benjamin ; Wade, Kaitlin H ; Haberland, Valeriia ; Baird, Denis ; Laurin, Charles ; Burgess, Stephen ; Bowden, Jack ; Langdon, Ryan ; Tan, Vanessa Y ; Yarmolinsky, James ; Shihab, Hashem A ; Timpson, Nicholas J ; Evans, David M ; Relton, Caroline ; Martin, Richard M ; Davey Smith, George ; Gaunt, Tom R ; Haycock, Philip C

eLife, 2018-05, Vol.7 [Periódico revisado por pares]

England: eLife Science Publications, Ltd

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2
Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011
Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011
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Genomic epidemiology of the Escherichia coli O104:H4 outbreaks in Europe, 2011

Grad, Yonatan H ; Lipsitch, Marc ; Feldgarden, Michael ; Arachchi, Harindra M ; Cerqueira, Gustavo C ; FitzGerald, Michael ; Godfrey, Paul ; Haas, Brian J ; Murphy, Cheryl I ; Russ, Carsten ; Sykes, Sean ; Walker, Bruce J ; Wortman, Jennifer R ; Young, Sarah ; Zeng, Qiandong ; Abouelleil, Amr ; Bochicchio, James ; Chauvin, Sara ; DeSmet, Timothy ; Gujja, Sharvari ; McCowan, Caryn ; Montmayeur, Anna ; Steelman, Scott ; Frimodt-Møller, Jakob ; Petersen, Andreas M ; Struve, Carsten ; Krogfelt, Karen A ; Bingen, Edouard ; Weill, François-Xavier ; Lander, Eric S ; Nusbaum, Chad ; Birren, Bruce W ; Hung, Deborah T ; Hanage, William P

Proceedings of the National Academy of Sciences - PNAS, 2012-02, Vol.109 (8), p.3065-3070 [Periódico revisado por pares]

United States: National Academy of Sciences

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3
Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies
Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies
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Polygenic adaptation on height is overestimated due to uncorrected stratification in genome-wide association studies

Sohail, Mashaal ; Maier, Robert M ; Ganna, Andrea ; Bloemendal, Alex ; Martin, Alicia R ; Turchin, Michael C ; Chiang, Charleston Wk ; Hirschhorn, Joel ; Daly, Mark J ; Patterson, Nick ; Neale, Benjamin ; Mathieson, Iain ; Reich, David ; Sunyaev, Shamil R

eLife, 2019-03, Vol.8 [Periódico revisado por pares]

England: eLife Science Publications, Ltd

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4
Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53
Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53
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Mechanistic basis for impaired ferroptosis in cells expressing the African-centric S47 variant of p53

Leu, Julia I-Ju ; Murphy, Maureen E. ; George, Donna L.

Proceedings of the National Academy of Sciences - PNAS, 2019-04, Vol.116 (17), p.8390-8396 [Periódico revisado por pares]

United States: National Academy of Sciences

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5
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans
Hunter-gatherer genomic diversity suggests a southern African origin for modern humans
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Hunter-gatherer genomic diversity suggests a southern African origin for modern humans

Henn, Brenna M ; Gignoux, Christopher R ; Jobin, Matthew ; Granka, Julie M ; Macpherson, J.M ; Kidd, Jeffrey M ; Rodríguez-Botigué, Laura ; Ramachandran, Sohini ; Hon, Lawrence ; Brisbin, Abra ; Lin, Alice A ; Underhill, Peter A ; Comas, David ; Kidd, Kenneth K ; Norman, Paul J ; Parham, Peter ; Bustamante, Carlos D ; Mountain, Joanna L ; Feldman, Marcus W

Proceedings of the National Academy of Sciences - PNAS, 2011-03, Vol.108 (13), p.5154-5162 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans
Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans
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Common oxytocin receptor gene (OXTR) polymorphism and social support interact to reduce stress in humans

Chen, Frances S ; Kumsta, Robert ; von Dawans, Bernadette ; Monakhov, Mikhail ; Ebstein, Richard P ; Heinrichs, Markus

Proceedings of the National Academy of Sciences - PNAS, 2011-12, Vol.108 (50), p.19937-19942 [Periódico revisado por pares]

United States: National Academy of Sciences

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7
Evolutionary dynamics of Staphylococcus aureus during progression from carriage to disease
Evolutionary dynamics of Staphylococcus aureus during progression from carriage to disease
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Evolutionary dynamics of Staphylococcus aureus during progression from carriage to disease

Young, Bernadette C ; Golubchik, Tanya ; Batty, Elizabeth M ; Fung, Rowena ; Larner-Svensson, Hanna ; Votintseva, Antonina A ; Miller, Ruth R ; Godwin, Heather ; Knox, Kyle ; Everitt, Richard G ; Iqbal, Zamin ; Rimmer, Andrew J ; Cule, Madeleine ; Ip, Camilla L. C ; Didelot, Xavier ; Harding, Rosalind M ; Donnelly, Peter ; Peto, Tim E ; Crook, Derrick W ; Bowden, Rory ; Wilson, Daniel J

Proceedings of the National Academy of Sciences - PNAS, 2012-03, Vol.109 (12), p.4550-4555 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants
Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants
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Distribution of allele frequencies and effect sizes and their interrelationships for common genetic susceptibility variants

Park, Ju-Hyun ; Gail, Mitchell H ; Weinberg, Clarice R ; Carroll, Raymond J ; Chung, Charles C ; Wang, Zhaoming ; Chanock, Stephen J ; Fraumeni, Joseph F. Jr ; Chatterjee, Nilanjan

Proceedings of the National Academy of Sciences - PNAS, 2011-11, Vol.108 (44), p.18026-18031 [Periódico revisado por pares]

United States: National Academy of Sciences

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9
Polygenic Risk Scores That Predict Common Diseases Using Millions of Single Nucleotide Polymorphisms: Is More, Better?
Polygenic Risk Scores That Predict Common Diseases Using Millions of Single Nucleotide Polymorphisms: Is More, Better?
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Polygenic Risk Scores That Predict Common Diseases Using Millions of Single Nucleotide Polymorphisms: Is More, Better?

Janssens, A Cecile JW ; Joyner, Michael J

Clinical chemistry (Baltimore, Md.), 2019-05, Vol.65 (5), p.609-611 [Periódico revisado por pares]

England: American Association for Clinical Chemistry, Inc

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10
Whole-genome nucleotide diversity, recombination, and linkage disequilibrium in the model legume Medicago truncatula
Whole-genome nucleotide diversity, recombination, and linkage disequilibrium in the model legume Medicago truncatula
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Whole-genome nucleotide diversity, recombination, and linkage disequilibrium in the model legume Medicago truncatula

Branca, Antoine ; Paape, Timothy D ; Zhou, Peng ; Briskine, Roman ; Farmer, Andrew D ; Mudge, Joann ; Bharti, Arvind K ; Woodward, Jimmy E ; May, Gregory D ; Gentzbittel, Laurent ; Ben, Cécile ; Denny, Roxanne ; Sadowsky, Michael J ; Ronfort, Joëlle ; Bataillon, Thomas ; Young, Nevin D ; Tiffin, Peter

Proceedings of the National Academy of Sciences - PNAS, 2011-10, Vol.108 (42), p.E864-E870 [Periódico revisado por pares]

United States: National Academy of Sciences

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