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Material Type: Artigo
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Higher adiposity and mental health: causal inference using Mendelian randomizationCasanova, Francesco ; O’Loughlin, Jessica ; Martin, Susan ; Beaumont, Robin N ; Wood, Andrew R ; Watkins, Edward R ; Freathy, Rachel M ; Hagenaars, Saskia P ; Frayling, Timothy M ; Yaghootkar, Hanieh ; Tyrrell, JessHuman molecular genetics, 2021-11, Vol.30 (24), p.2371-2382 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Human aging is characterized by focused changes in gene expression and deregulation of alternative splicingHarries, Lorna W. ; Hernandez, Dena ; Henley, William ; Wood, Andrew R. ; Holly, Alice C. ; Bradley‐Smith, Rachel M. ; Yaghootkar, Hanieh ; Dutta, Ambarish ; Murray, Anna ; Frayling, Timothy M. ; Guralnik, Jack M. ; Bandinelli, Stefania ; Singleton, Andrew ; Ferrucci, Luigi ; Melzer, DavidAging cell, 2011-10, Vol.10 (5), p.868-878 [Periódico revisado por pares]Oxford, UK: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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A Common Allele in FGF21 Associated with Sugar Intake Is Associated with Body Shape, Lower Total Body-Fat Percentage, and Higher Blood PressureFrayling, Timothy M. ; Beaumont, Robin N. ; Jones, Samuel E. ; Yaghootkar, Hanieh ; Tuke, Marcus A. ; Ruth, Katherine S. ; Casanova, Francesco ; West, Ben ; Locke, Jonathan ; Sharp, Seth ; Ji, Yingjie ; Thompson, William ; Harrison, Jamie ; Etheridge, Amy S. ; Gallins, Paul J. ; Jima, Dereje ; Wright, Fred ; Zhou, Yihui ; Innocenti, Federico ; Lindgren, Cecilia M. ; Grarup, Niels ; Murray, Anna ; Freathy, Rachel M. ; Weedon, Michael N. ; Tyrrell, Jessica ; Wood, Andrew R.Cell reports (Cambridge), 2018-04, Vol.23 (2), p.327-336 [Periódico revisado por pares]United States: Elsevier IncTexto completo disponível |
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Material Type: Artigo
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Meta-analysis of genome-wide association studies for body fat distribution in 694 649 individuals of European ancestryPulit, Sara L ; Stoneman, Charli ; Morris, Andrew P ; Wood, Andrew R ; Glastonbury, Craig A ; Tyrrell, Jessica ; Yengo, Loïc ; Ferreira, Teresa ; Marouli, Eirini ; Ji, Yingjie ; Yang, Jian ; Jones, Samuel ; Beaumont, Robin ; Croteau-Chonka, Damien C ; Winkler, Thomas W ; Hattersley, Andrew T ; Loos, Ruth J F ; Hirschhorn, Joel N ; Visscher, Peter M ; Frayling, Timothy M ; Yaghootkar, Hanieh ; Lindgren, Cecilia MHuman molecular genetics, 2019-01, Vol.28 (1), p.166-174 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Disease consequences of higher adiposity uncoupled from its adverse metabolic effects using Mendelian randomisationMartin, Susan ; Tyrrell, Jessica ; Thomas, E Louise ; Bown, Matthew J ; Wood, Andrew R ; Beaumont, Robin N ; Tsoi, Lam C ; Stuart, Philip E ; Elder, James T ; Law, Philip ; Houlston, Richard ; Kabrhel, Christopher ; Papadimitriou, Nikos ; Gunter, Marc J ; Bull, Caroline J ; Bell, Joshua A ; Vincent, Emma E ; Sattar, Naveed ; Dunlop, Malcolm G ; Tomlinson, Ian P M ; Lindström, Sara ; Bell, Jimmy D ; Frayling, Timothy M ; Yaghootkar, HanieheLife, 2022-01, Vol.11 [Periódico revisado por pares]England: eLife Sciences Publications LtdTexto completo disponível |
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Material Type: Artigo
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Height, body mass index, and socioeconomic status: mendelian randomisation study in UK BiobankTyrrell, Jessica ; Jones, Samuel E ; Beaumont, Robin ; Astley, Christina M ; Lovell, Rebecca ; Yaghootkar, Hanieh ; Tuke, Marcus ; Ruth, Katherine S ; Freathy, Rachel M ; Hirschhorn, Joel N ; Wood, Andrew R ; Murray, Anna ; Weedon, Michael N ; Frayling, Timothy MBMJ (Online), 2016-03, Vol.352, p.i582-i582 [Periódico revisado por pares]England: BMJ Publishing Group LTDTexto completo disponível |
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Material Type: Artigo
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Using genetics to understand the causal influence of higher BMI on depressionTyrrell, Jessica ; Mulugeta, Anwar ; Wood, Andrew R ; Zhou, Ang ; Beaumont, Robin N ; Tuke, Marcus A ; Jones, Samuel E ; Ruth, Katherine S ; Yaghootkar, Hanieh ; Sharp, Seth ; Thompson, William D ; Ji, Yingjie ; Harrison, Jamie ; Freathy, Rachel M ; Murray, Anna ; Weedon, Michael N ; Lewis, Cathryn ; Frayling, Timothy M ; Hyppönen, ElinaInternational journal of epidemiology, 2019-06, Vol.48 (3), p.834-848 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Gene-obesogenic environment interactions in the UK Biobank studyTyrrell, Jessica ; Wood, Andrew R ; Ames, Ryan M ; Yaghootkar, Hanieh ; Beaumont, Robin N ; Jones, Samuel E ; Tuke, Marcus A ; Ruth, Katherine S ; Freathy, Rachel M ; Davey Smith, George ; Joost, Stéphane ; Guessous, Idris ; Murray, Anna ; Strachan, David P ; Kutalik, Zoltán ; Weedon, Michael N ; Frayling, Timothy MInternational journal of epidemiology, 2017-04, Vol.46 (2), p.559-575 [Periódico revisado por pares]England: Oxford University PressTexto completo disponível |
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Material Type: Artigo
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Genetic Evidence for Different Adiposity Phenotypes and Their Opposing Influences on Ectopic Fat and Risk of Cardiometabolic DiseaseMartin, Susan ; Cule, Madeleine ; Basty, Nicolas ; Tyrrell, Jessica ; Beaumont, Robin N ; Wood, Andrew R ; Frayling, Timothy M ; Sorokin, Elena ; Whitcher, Brandon ; Liu, Yi ; Bell, Jimmy D ; Thomas, E Louise ; Yaghootkar, HaniehDiabetes (New York, N.Y.), 2021-08, Vol.70 (8), p.1843-1856 [Periódico revisado por pares]United States: American Diabetes AssociationTexto completo disponível |
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10 |
Material Type: Artigo
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Genetic Evidence for a Link Between Favorable Adiposity and Lower Risk of Type 2 Diabetes, Hypertension, and Heart DiseaseYaghootkar, Hanieh ; Lotta, Luca A ; Tyrrell, Jessica ; Smit, Roelof A J ; Jones, Sam E ; Donnelly, Louise ; Beaumont, Robin ; Campbell, Archie ; Tuke, Marcus A ; Hayward, Caroline ; Ruth, Katherine S ; Padmanabhan, Sandosh ; Jukema, J Wouter ; Palmer, Colin C ; Hattersley, Andrew ; Freathy, Rachel M ; Langenberg, Claudia ; Wareham, Nicholas J ; Wood, Andrew R ; Murray, Anna ; Weedon, Michael N ; Sattar, Naveed ; Pearson, Ewan ; Scott, Robert A ; Frayling, Timothy MDiabetes (New York, N.Y.), 2016-08, Vol.65 (8), p.2448-2460 [Periódico revisado por pares]United States: American Diabetes AssociationTexto completo disponível |