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Engineering the serpin α1‐antitrypsin: A diversity of goals and techniques
Engineering the serpin α1‐antitrypsin: A diversity of goals and techniques
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Engineering the serpin α1‐antitrypsin: A diversity of goals and techniques

Scott, Benjamin M. ; Sheffield, William P.

Protein science, 2020-04, Vol.29 (4), p.856-871 [Periódico revisado por pares]

Hoboken, USA: John Wiley & Sons, Inc

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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing
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Discovery of SARS-CoV-2 antiviral drugs through large-scale compound repurposing

Riva, Laura ; Yuan, Shuofeng ; Yin, Xin ; Martin-Sancho, Laura ; Matsunaga, Naoko ; Pache, Lars ; Burgstaller-Muehlbacher, Sebastian ; De Jesus, Paul D ; Teriete, Peter ; Hull, Mitchell V ; Chang, Max W ; Chan, Jasper Fuk-Woo ; Cao, Jianli ; Poon, Vincent Kwok-Man ; Herbert, Kristina M ; Cheng, Kuoyuan ; Nguyen, Tu-Trinh H ; Rubanov, Andrey ; Pu, Yuan ; Nguyen, Courtney ; Choi, Angela ; Rathnasinghe, Raveen ; Schotsaert, Michael ; Miorin, Lisa ; Dejosez, Marion ; Zwaka, Thomas P ; Sit, Ko-Yung ; Martinez-Sobrido, Luis ; Liu, Wen-Chun ; White, Kris M ; Chapman, Mackenzie E ; Lendy, Emma K ; Glynne, Richard J ; Albrecht, Randy ; Ruppin, Eytan ; Mesecar, Andrew D ; Johnson, Jeffrey R ; Benner, Christopher ; Sun, Ren ; Schultz, Peter G ; Su, Andrew I ; García-Sastre, Adolfo ; Chatterjee, Arnab K ; Yuen, Kwok-Yung ; Chanda, Sumit K

Nature (London), 2020-10, Vol.586 (7827), p.113-119 [Periódico revisado por pares]

England: Nature Publishing Group

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3
Camostat mesylate against SARS‐CoV‐2 and COVID‐19—Rationale, dosing and safety
Camostat mesylate against SARS‐CoV‐2 and COVID‐19—Rationale, dosing and safety
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Camostat mesylate against SARS‐CoV‐2 and COVID‐19—Rationale, dosing and safety

Breining, Peter ; Frølund, Anne Lier ; Højen, Jesper Falkesgaard ; Gunst, Jesper Damsgaard ; Staerke, Nina B. ; Saedder, Eva ; Cases‐Thomas, Manuel ; Little, Paul ; Nielsen, Lars Peter ; Søgaard, Ole S. ; Kjolby, Mads

Basic & clinical pharmacology & toxicology, 2021-02, Vol.128 (2), p.204-212 [Periódico revisado por pares]

England: Wiley Subscription Services, Inc

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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2
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Masitinib is a broad coronavirus 3CL inhibitor that blocks replication of SARS-CoV-2

Drayman, Nir ; DeMarco, Jennifer K ; Jones, Krysten A ; Azizi, Saara-Anne ; Froggatt, Heather M ; Tan, Kemin ; Maltseva, Natalia Ivanovna ; Chen, Siquan ; Nicolaescu, Vlad ; Dvorkin, Steve ; Furlong, Kevin ; Kathayat, Rahul S ; Firpo, Mason R ; Mastrodomenico, Vincent ; Bruce, Emily A ; Schmidt, Madaline M ; Jedrzejczak, Robert ; Muñoz-Alía, Miguel Á ; Schuster, Brooke ; Nair, Vishnu ; Han, Kyu-Yeon ; O'Brien, Amornrat ; Tomatsidou, Anastasia ; Meyer, Bjoern ; Vignuzzi, Marco ; Missiakas, Dominique ; Botten, Jason W ; Brooke, Christopher B ; Lee, Hyun ; Baker, Susan C ; Mounce, Bryan C ; Heaton, Nicholas S ; Severson, William E ; Palmer, Kenneth E ; Dickinson, Bryan C ; Joachimiak, Andrzej ; Randall, Glenn ; Tay, Savaş

Science (American Association for the Advancement of Science), 2021-08, Vol.373 (6557), p.931-936 [Periódico revisado por pares]

United States: The American Association for the Advancement of Science

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5
Organic Carbamates in Drug Design and Medicinal Chemistry
Organic Carbamates in Drug Design and Medicinal Chemistry
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Organic Carbamates in Drug Design and Medicinal Chemistry

Ghosh, Arun K ; Brindisi, Margherita

Journal of medicinal chemistry, 2015-04, Vol.58 (7), p.2895-2940 [Periódico revisado por pares]

United States: American Chemical Society

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6
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
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Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases

Powers, James C ; Asgian, Juliana L ; Ekici, Özlem Doǧan ; James, Karen Ellis

Chemical reviews, 2002-12, Vol.102 (12), p.4639-4750 [Periódico revisado por pares]

United States: American Chemical Society

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7
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
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SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase

Zheng, Qinheng ; Woehl, Jordan L. ; Kitamura, Seiya ; Santos-Martins, Diogo ; Smedley, Christopher J. ; Li, Gencheng ; Forli, Stefano ; Moses, John E. ; Wolan, Dennis W. ; Sharpless, K. Barry

Proceedings of the National Academy of Sciences - PNAS, 2019-09, Vol.116 (38), p.18808-18814 [Periódico revisado por pares]

United States: National Academy of Sciences

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8
Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases
Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases
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Tanshinones as selective and slow-binding inhibitors for SARS-CoV cysteine proteases

Park, Ji-Young ; Kim, Jang Hoon ; Kim, Young Min ; Jeong, Hyung Jae ; Kim, Dae Wook ; Park, Ki Hun ; Kwon, Hyung-Jun ; Park, Su-Jin ; Lee, Woo Song ; Ryu, Young Bae

Bioorganic & medicinal chemistry, 2012-10, Vol.20 (19), p.5928-5935 [Periódico revisado por pares]

Amsterdam: Elsevier Ltd

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9
Characterization of a serine protease inhibitor from Trichinella spiralis and its participation in larval invasion of host's intestinal epithelial cells
Characterization of a serine protease inhibitor from Trichinella spiralis and its participation in larval invasion of host's intestinal epithelial cells
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Characterization of a serine protease inhibitor from Trichinella spiralis and its participation in larval invasion of host's intestinal epithelial cells

Song, Yan Yan ; Zhang, Yao ; Ren, Hua Nan ; Sun, Ge Ge ; Qi, Xin ; Yang, Fan ; Jiang, Peng ; Zhang, Xi ; Cui, Jing ; Wang, Zhong Quan

Parasites & vectors, 2018-09, Vol.11 (1), p.499-499, Article 499 [Periódico revisado por pares]

England: BioMed Central Ltd

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10
Characterization and function analysis of a Kazal-type serine proteinase inhibitor in the red claw crayfish Cherax quadricarinatus
Characterization and function analysis of a Kazal-type serine proteinase inhibitor in the red claw crayfish Cherax quadricarinatus
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Characterization and function analysis of a Kazal-type serine proteinase inhibitor in the red claw crayfish Cherax quadricarinatus

Wang, Yan ; Wang, Baojie ; Liu, Mei ; Jiang, Keyong ; Wang, Mengqiang ; Wang, Lei

Developmental and comparative immunology, 2021-01, Vol.114, p.103871-103871, Article 103871 [Periódico revisado por pares]

United States: Elsevier Ltd

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