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1 |
Material Type: Artigo
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α-synuclein toxicity in neurodegeneration: mechanism and therapeutic strategiesWong, Yvette C ; Krainc, DimitriNature medicine, 2017-02, Vol.23 (2), p.1-13 [Periódico revisado por pares]United StatesTexto completo disponível |
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2 |
Material Type: Artigo
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α-Synuclein promotes dilation of the exocytotic fusion poreLogan, Todd ; Bendor, Jacob ; Toupin, Chantal ; Thorn, Kurt ; Edwards, Robert HNature neuroscience, 2017-05, Vol.20 (5), p.681-689 [Periódico revisado por pares]United StatesTexto completo disponível |
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3 |
Material Type: Artigo
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The mechanism of sirtuin 2-mediated exacerbation of alpha-synuclein toxicity in models of Parkinson diseasede Oliveira, Rita Machado ; Vicente Miranda, Hugo ; Francelle, Laetitia ; Pinho, Raquel ; Szegö, Éva M ; Martinho, Renato ; Munari, Francesca ; Lázaro, Diana F ; Moniot, Sébastien ; Guerreiro, Patrícia ; Fonseca-Ornelas, Luis ; Marijanovic, Zrinka ; Antas, Pedro ; Gerhardt, Ellen ; Enguita, Francisco Javier ; Fauvet, Bruno ; Penque, Deborah ; Pais, Teresa Faria ; Tong, Qiang ; Becker, Stefan ; Kügler, Sebastian ; Lashuel, Hilal Ahmed ; Steegborn, Clemens ; Zweckstetter, Markus ; Outeiro, Tiago Fleming Bates, GillianPLoS biology, 2017-03, Vol.15 (3), p.e2000374 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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The many faces of α-synuclein: from structure and toxicity to therapeutic targetLashuel, Hilal A ; Overk, Cassia R ; Oueslati, Abid ; Masliah, EliezerNature reviews. Neuroscience, 2013-01, Vol.14 (1), p.38-48 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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5 |
Material Type: Artigo
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Alpha‐synuclein promotes PRMT5‐mediated H4R3me2s histone methylation by interacting with the BAF complexNakamura, Takaaki ; Sugeno, Naoto ; Hasegawa, Takafumi ; Ikeda, Kensho ; Yoshida, Shun ; Ishiyama, Shun ; Sato, Kazuki ; Takeda, Atsushi ; Aoki, MasashiThe FEBS journal, 2024-05, Vol.291 (9), p.1892-1908 [Periódico revisado por pares]England: Blackwell Publishing LtdTexto completo disponível |
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Material Type: Artigo
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Solid-state NMR structure of a pathogenic fibril of full-length human α-synucleinTuttle, Marcus D ; Comellas, Gemma ; Nieuwkoop, Andrew J ; Covell, Dustin J ; Berthold, Deborah A ; Kloepper, Kathryn D ; Courtney, Joseph M ; Kim, Jae K ; Barclay, Alexander M ; Kendall, Amy ; Wan, William ; Stubbs, Gerald ; Schwieters, Charles D ; Lee, Virginia M Y ; George, Julia M ; Rienstra, Chad MNature structural & molecular biology, 2016-05, Vol.23 (5), p.409-415 [Periódico revisado por pares]United States: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Abnormal Salivary Total and Oligomeric Alpha-Synuclein in Parkinson's DiseaseVivacqua, Giorgio ; Latorre, Anna ; Suppa, Antonio ; Nardi, Michela ; Pietracupa, Sara ; Mancinelli, Romina ; Fabbrini, Giovanni ; Colosimo, Carlo ; Gaudio, Eugenio ; Berardelli, Alfredo Kahle, Philipp J.PloS one, 2016-03, Vol.11 (3), p.e0151156 [Periódico revisado por pares]United States: Public Library of ScienceTexto completo disponível |
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Material Type: Artigo
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Brain regions susceptible to alpha-synuclein spreadingGuo, Yu-Jie ; Xiong, Huan ; Chen, Kang ; Zou, Jin-Jun ; Lei, PengMolecular psychiatry, 2022-01, Vol.27 (1), p.758-770 [Periódico revisado por pares]England: Nature Publishing GroupTexto completo disponível |
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Material Type: Artigo
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Structures of α-synuclein filaments from multiple system atrophySchweighauser, Manuel ; Shi, Yang ; Tarutani, Airi ; Kametani, Fuyuki ; Murzin, Alexey G ; Ghetti, Bernardino ; Matsubara, Tomoyasu ; Tomita, Taisuke ; Ando, Takashi ; Hasegawa, Kazuko ; Murayama, Shigeo ; Yoshida, Mari ; Hasegawa, Masato ; Scheres, Sjors H W ; Goedert, MichelNature (London), 2020-09, Vol.585 (7825), p.464-469 [Periódico revisado por pares]EnglandTexto completo disponível |
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10 |
Material Type: Artigo
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Reducing [alpha]-synuclein accumulationCrunkhorn, SarahNature reviews. Drug discovery, 2020-03, Vol.19 (3) [Periódico revisado por pares]Nature Publishing GroupTexto completo disponível |