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Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial
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Intensive blood pressure reduction with intravenous thrombolysis therapy for acute ischaemic stroke (ENCHANTED): an international, randomised, open-label, blinded-endpoint, phase 3 trial

Anderson, Craig S ; Arima, Hisatomi ; Chen, Guofang ; Martins, Sheila O ; Silva, Federico ; Thang, Nguyen H ; Arima, Hisatomi ; Li, Qiang ; Martins, Sheila O. ; Pontes-Neto, Octavio M. ; Wang, Xia ; Simes, R. John ; Hirakawa, Yoichiro ; Moullaali, Tom J. ; Carcel, Cheryl ; Gordon, Penny ; Cao, Yongjun ; Winters, Stephen ; Zhang, Shihong ; Manning, Lisa ; Minhas, Jatinder ; Malavera, Alejandra ; Ivanova, Elizaveta ; Armenis, Manuela ; Blacklock, Nick ; Naidu, Bala ; Smith, Phillipa ; Kong, Liang ; Ebraimo, Ahtasam ; Phuong, Do M. ; Tran, Nguyen T.B. ; Hoa, Nguyen A. ; Ray, E. ; Ng, G. ; Weiss, G. ; Titton, N. ; Castro, R. ; Fagundes, D. ; Alves, M. ; Rivas, R. ; Herrera, A. ; Zhou, S. ; Ping, L. ; Shi, J. ; Gong, P. ; Zhao, H. ; Li, R. ; Liu, D. ; Liang, L. ; Xia, J. ; Zhao, N. ; Huang, W. ; Zhang, A. ; Liu, H. ; Zhang, Y. ; Li, F. ; Huang, L. ; Zheng, R. ; Liu, J. ; Zhang, S. ; Liu, X. ; Lai, Y. ; Du, J. ; Wei, C. ; Li, W ; Zeng, X. ; Wu, X. ; Castellanos, J.A. ; Raj, P.G. ; Parmar, M. ; Patel, D. ; Gorthi, S.P. ; Prabhu, A. ; Nair, R. ; TP, S. ; Choudhury, N. ; Duberkar, D. ; Sacchini, E. ; Padiglioni, C. ; Kim, J. ; Hwang, H.W. ; Kwon, S.U. ; Kim, Y.J. ; Kim, B. ; Kim, Y.W. ; Lee, J.J. ; Chang, H.M. ; Martínez, A. ; Lin, Y.J. ; Huang, Y.C. ; Dyker, A. ; Natarajan, I. ; Qadiri, M.R. ; Smith, C. ; James, M. ; Marsden, T. ; Price, C. ; Bergin, A. ; Le Kim, K. ; Le Thanh, T. Tran

The Lancet (British edition), 2019-03, Vol.393 (10174), p.877-888 [Periódico revisado por pares]

England: Elsevier Ltd

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2
Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial
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Intraoperative ketamine for prevention of postoperative delirium or pain after major surgery in older adults: an international, multicentre, double-blind, randomised clinical trial

Avidan, Michael S, Dr Prof ; Maybrier, Hannah R, BS ; Abdallah, Arbi Ben, PhD ; Jacobsohn, Eric, Prof ; Vlisides, Phillip E, MD ; Pryor, Kane O, MBBS ; Veselis, Robert A, Prof ; Grocott, Hillary P, Prof ; Emmert, Daniel A, MD ; Rogers, Emma M, BS ; Downey, Robert J, MD ; Yulico, Heidi, DNP ; Noh, Gyu-Jeong, Prof ; Lee, Yonghun H, MD ; Waszynski, Christine M, DNP ; Arya, Virendra K, Prof ; Pagel, Paul S, Prof ; Hudetz, Judith A, PhD ; Muench, Maxwell R, BS ; Fritz, Bradley A, MD ; Waberski, Witold, MD ; Inouye, Sharon K, Prof ; Mashour, George A, Prof

The Lancet (British edition), 2017-07, Vol.390 (10091), p.267-275 [Periódico revisado por pares]

England: Elsevier Ltd

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3
Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes: A Randomized Clinical Trial
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Effect of Metformin Added to Insulin on Glycemic Control Among Overweight/Obese Adolescents With Type 1 Diabetes: A Randomized Clinical Trial

Libman, Ingrid M ; Miller, Kellee M ; DiMeglio, Linda A ; Bethin, Kathleen E ; Katz, Michelle L ; Shah, Avni ; Simmons, Jill H ; Haller, Michael J ; Raman, Sripriya ; Tamborlane, William V ; Coffey, Julie K ; Saenz, Ashleigh M ; Beck, Roy W ; Nadeau, Kristen J

JAMA : the journal of the American Medical Association, 2015-12, Vol.314 (21), p.2241-2250 [Periódico revisado por pares]

United States: American Medical Association

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4
Prevalence and treatment of opioid use disorders among primary care patients in six health systems
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Prevalence and treatment of opioid use disorders among primary care patients in six health systems

Lapham, Gwen ; Boudreau, Denise M. ; Johnson, Eric A. ; Bobb, Jennifer F. ; Matthews, Abigail G. ; McCormack, Jennifer ; Liu, David ; Samet, Jeffrey H. ; Saxon, Andrew J. ; Campbell, Cynthia I. ; Glass, Joseph E. ; Rossom, Rebecca C. ; Murphy, Mark T. ; Binswanger, Ingrid A. ; Yarborough, Bobbi Jo H. ; Bradley, Katharine A. ; Ahmedani, Brian ; Amoroso, Paul J. ; Arnsten, Julia H. ; Bart, Gavin ; Braciszewski, Jordan M. ; Cunningham, Chinazo O. ; Hechter, Rulin C. ; Horigian, Viviana E. ; Liebschutz, Jane M. ; Loree, Amy M. ; Matson, Theresa E. ; McNeely, Jennifer ; Merrill, Joseph O. ; Northrup, Thomas F. ; Schwartz, Robert P. ; Stotts, Angela L. ; Szapocznik, José ; Thakral, Manu ; Tsui, Judith I. ; Zare, Mohammad

Drug and alcohol dependence, 2020-02, Vol.207, p.107732-107732, Article 107732 [Periódico revisado por pares]

Ireland: Elsevier B.V

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5
Racial-ethnic disparities in management and outcomes among children with type 1 diabetes
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Racial-ethnic disparities in management and outcomes among children with type 1 diabetes

Willi, Steven M ; Miller, Kellee M ; DiMeglio, Linda A ; Klingensmith, Georgeanna J ; Simmons, Jill H ; Tamborlane, William V ; Nadeau, Kristen J ; Kittelsrud, Julie M ; Huckfeldt, Peter ; Beck, Roy W ; Lipman, Terri H

Pediatrics (Evanston), 2015-03, Vol.135 (3), p.424-434 [Periódico revisado por pares]

United States: American Academy of Pediatrics

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6
Secukinumab administration by pre-filled syringe: efficacy, safety and usability results from a randomized controlled trial in psoriasis (FEATURE)
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Secukinumab administration by pre-filled syringe: efficacy, safety and usability results from a randomized controlled trial in psoriasis (FEATURE)

Blauvelt, A. ; Prinz, J.C. ; Gottlieb, A.B. ; Kingo, K. ; Sofen, H. ; Ruer-Mulard, M. ; Singh, V. ; Pathan, R. ; Papavassilis, C. ; Cooper, S.

British journal of dermatology (1951), 2015-02, Vol.172 (2), p.484-493 [Periódico revisado por pares]

England: Blackwell Publishing Ltd

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7
Effect of Continuous Glucose Monitoring on Glycemic Control in Patients With Type 2 Diabetes Treated With Basal Insulin: A Randomized Clinical Trial
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Effect of Continuous Glucose Monitoring on Glycemic Control in Patients With Type 2 Diabetes Treated With Basal Insulin: A Randomized Clinical Trial

Martens, Thomas ; Beck, Roy W ; Bailey, Ryan ; Ruedy, Katrina J ; Calhoun, Peter ; Peters, Anne L ; Pop-Busui, Rodica ; Philis-Tsimikas, Athena ; Bao, Shichun ; Umpierrez, Guillermo ; Davis, Georgia ; Kruger, Davida ; Bhargava, Anuj ; Young, Laura ; McGill, Janet B ; Aleppo, Grazia ; Nguyen, Quang T ; Orozco, Ian ; Biggs, William ; Lucas, K. Jean ; Polonsky, William H ; Buse, John B ; Price, David ; Bergenstal, Richard M

JAMA : the journal of the American Medical Association, 2021-06, Vol.325 (22), p.2262-2272 [Periódico revisado por pares]

United States: American Medical Association

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8
Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen
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Community assessment to advance computational prediction of cancer drug combinations in a pharmacogenomic screen

Menden, Michael P ; Wang, Dennis ; Mason, Mike J ; Szalai, Bence ; Bulusu, Krishna C ; Guan, Yuanfang ; Yu, Thomas ; Kang, Jaewoo ; Jeon, Minji ; Wolfinger, Russ ; Nguyen, Tin ; Zaslavskiy, Mikhail ; Jang, In Sock ; Ghazoui, Zara ; Ahsen, Mehmet Eren ; Vogel, Robert ; Neto, Elias Chaibub ; Norman, Thea ; Tang, Eric K Y ; Garnett, Mathew J ; Veroli, Giovanni Y Di ; Fawell, Stephen ; Stolovitzky, Gustavo ; Guinney, Justin ; Dry, Jonathan R ; Saez-Rodriguez, Julio

Nature communications, 2019-06, Vol.10 (1), p.2674-17, Article 2674 [Periódico revisado por pares]

England: Nature Publishing Group

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9
Chronic migraine headache prevention with noninvasive vagus nerve stimulation: The EVENT study
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Chronic migraine headache prevention with noninvasive vagus nerve stimulation: The EVENT study

Silberstein, Stephen D ; Calhoun, Anne H ; Lipton, Richard B ; Grosberg, Brian M ; Cady, Roger K ; Dorlas, Stefanie ; Simmons, Kristy A ; Mullin, Chris ; Liebler, Eric J ; Goadsby, Peter J ; Saper, Joel R

Neurology, 2016-08, Vol.87 (5), p.529-538 [Periódico revisado por pares]

United States: American Academy of Neurology

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10
Effect of Vitamin E or Metformin for Treatment of Nonalcoholic Fatty Liver Disease in Children and Adolescents: The TONIC Randomized Controlled Trial
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Effect of Vitamin E or Metformin for Treatment of Nonalcoholic Fatty Liver Disease in Children and Adolescents: The TONIC Randomized Controlled Trial

Lavine, Joel E ; Schwimmer, Jeffrey B ; Van Natta, Mark L ; Molleston, Jean P ; Murray, Karen F ; Rosenthal, Philip ; Abrams, Stephanie H ; Scheimann, Ann O ; Sanyal, Arun J ; Chalasani, Naga ; Tonascia, James ; Ünalp, Aynur ; Clark, Jeanne M ; Brunt, Elizabeth M ; Kleiner, David E ; Hoofnagle, Jay H ; Robuck, Patricia R ; Nonalcoholic Steatohepatitis Clinical Research Network, for the

JAMA : the journal of the American Medical Association, 2011-04, Vol.305 (16), p.1659-1668 [Periódico revisado por pares]

United States: American Medical Association

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