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Potentiating KCC2 activity is sufficient to limit the onset and severity of seizures
Potentiating KCC2 activity is sufficient to limit the onset and severity of seizures
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Potentiating KCC2 activity is sufficient to limit the onset and severity of seizures

Moore, Yvonne E. ; Deeb, Tarek Z. ; Chadchankar, Heramb ; Brandon, Nicholas J. ; Moss, Stephen J.

Proceedings of the National Academy of Sciences - PNAS, 2018-10, Vol.115 (40), p.10166-10171 [Periódico revisado por pares]

United States: National Academy of Sciences

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2
Seizing Control of KCC2: A New Therapeutic Target for Epilepsy
Seizing Control of KCC2: A New Therapeutic Target for Epilepsy
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Seizing Control of KCC2: A New Therapeutic Target for Epilepsy

Moore, Yvonne E. ; Kelley, Matt R. ; Brandon, Nicholas J. ; Deeb, Tarek Z. ; Moss, Stephen J.

Trends in neurosciences (Regular ed.), 2017-09, Vol.40 (9), p.555-571 [Periódico revisado por pares]

England: Elsevier Ltd

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3
Modulation of neuronal activity by phosphorylation of the K–Cl cotransporter KCC2
Modulation of neuronal activity by phosphorylation of the K–Cl cotransporter KCC2
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Modulation of neuronal activity by phosphorylation of the K–Cl cotransporter KCC2

Kahle, Kristopher T ; Deeb, Tarek Z ; Puskarjov, Martin ; Silayeva, Liliya ; Liang, Bo ; Kaila, Kai ; Moss, Stephen J

Trends in neurosciences (Regular ed.), 2013-12, Vol.36 (12), p.726-737 [Periódico revisado por pares]

England: Elsevier Ltd

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4
NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents
NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents
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NMDA receptor activity downregulates KCC2 resulting in depolarizing GABAA receptor-mediated currents

Lee, Henry H C ; Deeb, Tarek Z ; Walker, Joshua A ; Davies, Paul A ; Moss, Stephen J

Nature neuroscience, 2011-06, Vol.14 (6), p.736-743 [Periódico revisado por pares]

United States: Nature Publishing Group

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5
KCC2 activity is critical in limiting the onset and severity of status epilepticus
KCC2 activity is critical in limiting the onset and severity of status epilepticus
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KCC2 activity is critical in limiting the onset and severity of status epilepticus

Silayeva, Liliya ; Deeb, Tarek Z. ; Hines, Rochelle M. ; Kelley, Matt R. ; Munoz, Michaelanne B. ; Lee, Henry H. C. ; Brandon, Nicholas J. ; Dunlop, John ; Maguire, Jaime ; Davies, Paul A. ; Moss, Stephen J.

Proceedings of the National Academy of Sciences - PNAS, 2015-03, Vol.112 (11), p.3523-3528 [Periódico revisado por pares]

United States: National Academy of Sciences

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6
L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks
L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks
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L-type voltage-gated calcium channel regulation of in vitro human cortical neuronal networks

Plumbly, William ; Brandon, Nick ; Deeb, Tarek Z ; Hall, Jeremy ; Harwood, Adrian J

Scientific reports, 2019-09, Vol.9 (1), p.13810-12, Article 13810 [Periódico revisado por pares]

England: Nature Publishing Group

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7
Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation
Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation
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Cyclin E Constrains Cdk5 Activity to Regulate Synaptic Plasticity and Memory Formation

Odajima, Junko ; Wills, Zachary P. ; Ndassa, Yasmine M. ; Terunuma, Miho ; Kretschmannova, Karla ; Deeb, Tarek Z. ; Geng, Yan ; Gawrzak, Sylwia ; Quadros, Isabel M. ; Newman, Jennifer ; Das, Manjusri ; Jecrois, Marie E. ; Yu, Qunyan ; Li, Na ; Bienvenu, Frederic ; Moss, Stephen J. ; Greenberg, Michael E. ; Marto, Jarrod A. ; Sicinski, Piotr

Developmental cell, 2011-10, Vol.21 (4), p.655-668 [Periódico revisado por pares]

Cambridge, MA: Elsevier Inc

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8
Compromising KCC2 transporter activity enhances the development of continuous seizure activity
Compromising KCC2 transporter activity enhances the development of continuous seizure activity
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Compromising KCC2 transporter activity enhances the development of continuous seizure activity

Kelley, Matthew R. ; Deeb, Tarek Z. ; Brandon, Nicholas J. ; Dunlop, John ; Davies, Paul A. ; Moss, Stephen J.

Neuropharmacology, 2016-09, Vol.108, p.103-110 [Periódico revisado por pares]

England: Elsevier Ltd

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9
Molecular architecture of potassium chloride co-transporter KCC2
Molecular architecture of potassium chloride co-transporter KCC2
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Molecular architecture of potassium chloride co-transporter KCC2

Agez, Morgane ; Schultz, Patrick ; Medina, Igor ; Baker, David J ; Burnham, Matthew P ; Cardarelli, Ross A ; Conway, Leslie C ; Garnier, Kelly ; Geschwindner, Stefan ; Gunnarsson, Anders ; McCall, Eileen J ; Frechard, Alexandre ; Audebert, Stéphane ; Deeb, Tarek Z ; Moss, Stephen J ; Brandon, Nicholas J ; Wang, Qi ; Dekker, Niek ; Jawhari, Anass

Scientific reports, 2017-11, Vol.7 (1), p.16452-14, Article 16452 [Periódico revisado por pares]

England: Nature Publishing Group

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10
Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway
Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway
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Small molecule inducers of ABCA1 and apoE that act through indirect activation of the LXR pathway

Fan, Jianjia ; Zhao, Rui Qi ; Parro, Cameron ; Zhao, Wenchen ; Chou, Hsien-Ya ; Robert, Jerome ; Deeb, Tarek Z. ; Raynoschek, Carina ; Barichievy, Samantha ; Engkvist, Ola ; Maresca, Marcello ; Hicks, Ryan ; Meuller, Johan ; Moss, Stephen J. ; Brandon, Nicholas J. ; Wood, Michael W. ; Kulic, Iva ; Wellington, Cheryl L.

Journal of lipid research, 2018-05, Vol.59 (5), p.830-842 [Periódico revisado por pares]

United States: Elsevier Inc

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