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Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment
Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment
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Lipidomic Analysis of α-Synuclein Neurotoxicity Identifies Stearoyl CoA Desaturase as a Target for Parkinson Treatment

Fanning, Saranna ; Haque, Aftabul ; Imberdis, Thibaut ; Baru, Valeriya ; Barrasa, M. Inmaculada ; Nuber, Silke ; Termine, Daniel ; Ramalingam, Nagendran ; Ho, Gary P.H. ; Noble, Tallie ; Sandoe, Jackson ; Lou, Yali ; Landgraf, Dirk ; Freyzon, Yelena ; Newby, Gregory ; Soldner, Frank ; Terry-Kantor, Elizabeth ; Kim, Tae-Eun ; Hofbauer, Harald F. ; Becuwe, Michel ; Jaenisch, Rudolf ; Pincus, David ; Clish, Clary B. ; Walther, Tobias C. ; Farese, Robert V. ; Srinivasan, Supriya ; Welte, Michael A. ; Kohlwein, Sepp D. ; Dettmer, Ulf ; Lindquist, Susan ; Selkoe, Dennis

Molecular cell, 2019-03, Vol.73 (5), p.1001-1014.e8 [Peer Reviewed Journal]

United States: Elsevier Inc

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2
Creatine biosynthesis and transport in health and disease
Creatine biosynthesis and transport in health and disease
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Creatine biosynthesis and transport in health and disease

Joncquel-Chevalier Curt, Marie ; Voicu, Pia-Manuela ; Fontaine, Monique ; Dessein, Anne-Frédérique ; Porchet, Nicole ; Mention-Mulliez, Karine ; Dobbelaere, Dries ; Soto-Ares, Gustavo ; Cheillan, David ; Vamecq, Joseph

Biochimie, 2015-12, Vol.119, p.146-165 [Peer Reviewed Journal]

France: Elsevier B.V

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3
The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection
The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection
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The 20S proteasome core, active within apoptotic exosome-like vesicles, induces autoantibody production and accelerates rejection

Dieudé, Mélanie ; Bell, Christina ; Turgeon, Julie ; Beillevaire, Deborah ; Pomerleau, Luc ; Yang, Bing ; Hamelin, Katia ; Qi, Shijie ; Pallet, Nicolas ; Béland, Chanel ; Dhahri, Wahiba ; Cailhier, Jean-François ; Rousseau, Matthieu ; Duchez, Anne-Claire ; Lévesque, Tania ; Lau, Arthur ; Rondeau, Christiane ; Gingras, Diane ; Muruve, Danie ; Rivard, Alain ; Cardinal, Héloise ; Perreault, Claude ; Desjardins, Michel ; Boilard, Éric ; Thibault, Pierre ; Hébert, Marie-Josée

Science translational medicine, 2015-12, Vol.7 (318), p.318ra200-318ra200 [Peer Reviewed Journal]

United States

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4
Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function
Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function
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Mannan-binding lectin-associated serine protease (MASP)-1 is crucial for lectin pathway activation in human serum, whereas neither MASP-1 nor MASP-3 is required for alternative pathway function

Degn, Søren E ; Jensen, Lisbeth ; Hansen, Annette G ; Duman, Duygu ; Tekin, Mustafa ; Jensenius, Jens C ; Thiel, Steffen

The Journal of immunology (1950), 2012-10, Vol.189 (8), p.3957-3969 [Peer Reviewed Journal]

United States

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5
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS
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Ischaemic accumulation of succinate controls reperfusion injury through mitochondrial ROS

Chouchani, Edward T ; Pell, Victoria R ; Gaude, Edoardo ; Aksentijević, Dunja ; Sundier, Stephanie Y ; Robb, Ellen L ; Logan, Angela ; Nadtochiy, Sergiy M ; Ord, Emily N J ; Smith, Anthony C ; Eyassu, Filmon ; Shirley, Rachel ; Hu, Chou-Hui ; Dare, Anna J ; James, Andrew M ; Rogatti, Sebastian ; Hartley, Richard C ; Eaton, Simon ; Costa, Ana S H ; Brookes, Paul S ; Davidson, Sean M ; Duchen, Michael R ; Saeb-Parsy, Kourosh ; Shattock, Michael J ; Robinson, Alan J ; Work, Lorraine M ; Frezza, Christian ; Krieg, Thomas ; Murphy, Michael P

Nature (London), 2014-11, Vol.515 (7527), p.431-435 [Peer Reviewed Journal]

England: Nature Publishing Group

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6
Aldehyde dehydrogenase (ALDH) superfamily in plants: gene nomenclature and comparative genomics
Aldehyde dehydrogenase (ALDH) superfamily in plants: gene nomenclature and comparative genomics
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Aldehyde dehydrogenase (ALDH) superfamily in plants: gene nomenclature and comparative genomics

Brocker, Chad ; Vasiliou, Melpomene ; Carpenter, Sarah ; Carpenter, Christopher ; Zhang, Yucheng ; Wang, Xiping ; Kotchoni, Simeon O. ; Wood, Andrew J. ; Kirch, Hans-Hubert ; Kopečný, David ; Nebert, Daniel W. ; Vasiliou, Vasilis

Planta, 2013-01, Vol.237 (1), p.189-210 [Peer Reviewed Journal]

Berlin/Heidelberg: Springer-Verlag

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7
Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons
Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons
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Reactive oxygen species regulate axonal regeneration through the release of exosomal NADPH oxidase 2 complexes into injured axons

Hervera, Arnau ; De Virgiliis, Francesco ; Palmisano, Ilaria ; Zhou, Luming ; Tantardini, Elena ; Kong, Guiping ; Hutson, Thomas ; Danzi, Matt C ; Perry, Rotem Ben-Tov ; Santos, Celio X C ; Kapustin, Alexander N ; Fleck, Roland A ; Del Río, José Antonio ; Carroll, Thomas ; Lemmon, Vance ; Bixby, John L ; Shah, Ajay M ; Fainzilber, Mike ; Di Giovanni, Simone

Nature cell biology, 2018-03, Vol.20 (3), p.307-319 [Peer Reviewed Journal]

England: Nature Publishing Group

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8
Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production
Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production
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Rac2 Modulates Atherosclerotic Calcification by Regulating Macrophage Interleukin-1β Production

Ceneri, Nicolle ; Zhao, Lina ; Young, Bryan D ; Healy, Abigail ; Coskun, Suleyman ; Vasavada, Hema ; Yarovinsky, Timur O ; Ike, Kenneth ; Pardi, Ruggero ; Qin, Lingfen ; Qin, Li ; Tellides, George ; Hirschi, Karen ; Meadows, Judith ; Soufer, Robert ; Chun, Hyung J ; Sadeghi, Mehran ; Bender, Jeffrey R ; Morrison, Alan R

Arteriosclerosis, thrombosis, and vascular biology, 2017-02, Vol.37 (2), p.328-340 [Peer Reviewed Journal]

United States: American Heart Association, Inc

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9
Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond
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Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond

Ilieva, Hristelina ; Polymenidou, Magdalini ; Cleveland, Don W

The Journal of cell biology, 2009-12, Vol.187 (6), p.761-772 [Peer Reviewed Journal]

United States: The Rockefeller University Press

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10
Matrix metalloproteinases as valid clinical targets
Matrix metalloproteinases as valid clinical targets
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Matrix metalloproteinases as valid clinical targets

Fingleton, Barbara

Current pharmaceutical design, 2007, Vol.13 (3), p.333-346 [Peer Reviewed Journal]

United Arab Emirates

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