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Spectral analysis of ocular pulse amplitude recordings obtained using a contact lens sensor.(Report)

Hirn, C ; Russell, Ra ; Lamparter, J ; Lascaratos, G ; Ho, T ; Garway - Heath, Df

Acta Ophthalmologica, August, 2013, Vol.91(s252), p.0(1) [Periódico revisado por pares]

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  • Título:
    Spectral analysis of ocular pulse amplitude recordings obtained using a contact lens sensor.(Report)
  • Autor: Hirn, C ; Russell, Ra ; Lamparter, J ; Lascaratos, G ; Ho, T ; Garway - Heath, Df
  • Assuntos: Sensors -- Analysis ; Ophthalmology -- Analysis ; Glaucoma -- Analysis
  • É parte de: Acta Ophthalmologica, August, 2013, Vol.91(s252), p.0(1)
  • Descrição: To purchase or authenticate to the full-text of this article, please visit this link: http://onlinelibrary.wiley.com/doi/10.1111/j.1755-3768.2013.2727.x/abstract Byline: C HIRN(1)-2727 (2)-2727, RA RUSSELL(2)-2727 (3)-2727, J LAMPARTER(4)-2727 (2)-2727, G LASCARATOS(2)-2727, T HO(2)-2727, DF GARWAY-HEATH(2)-2727 Abstract Purpose The aim of this study was to investigate whether the ocular pulse amplitude (OPA) can be detected in fluctuation curves recorded with the Sensimed Triggerfish[R] Sensor (TS), and analysed by Fast Fourier Transform (FFT). Methods 40 subjects (20 open angle glaucoma [OAG], 20 healthy) underwent one hour of TS monitoring. Intraocular pressure and OPA were measured by dynamic contour tonometry (DCT) and DCT OPA was used as the reference. Segments of TS OPA fluctuations were visually identified (VI), and the amplitude (mVequ) was measured (VI-TS OPA). In addition, FFT signal analysis, which reduces a periodic function into its frequency components, was performed on VI segments, and the amplitude (arbitrary units [AU]) of the fundamental measured (FFT-TS OPA). The correlation between VI- and FFT-TS OPA was investigated. VI- and FFT-TS OPA were compared with DCT OPA. Results In 3 subjects, TS recording failed. In 8 subjects, either no OPA or no fundamental could be identified. For the remaining 29 subjects (13 OAG, 16 healthy), both mean ([+ or -]standard deviation) VI- and FFT-TS OPA were lower in OAG (9.0[+ or -]3.9mVequ and 184.6[+ or -]303.7AU) than in healthy subjects (10.2[+ or -]4.5mVequ and 303.3[+ or -]292.0AU). Mean DCT OPA was higher in OAG (2.7[+ or -]0.8mmHg) than in healthy subjects (2.3[+ or -]0.6mmHg) (p>0.05 for all). There was a significant correlation between VI- and FFT-TS OPA (Spearman's rho=0.84; p 0.0001). In OAG subjects only, the correlation between VI-TS OPA and DCT OPA (Spearman's rho=0.52, p=0.072) and FFT-TS OPA and DCT OPA (Spearman's rho=0.48, p=0.099) approached significance. Conclusion It is possible to identify OPA in TS fluctuation curves and to analyse OPA by FFT. There is a weak association between TS OPA and DCT OPA in OAG. Author Affiliation: (1)-2727Ophthalmology, Triemli Hospital, Zurich (2)-2727NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London (3)-2727Optometry and Visual Science, City University, London (4)-2727Ophthalmology, University Medical Centre, Mainz
  • Idioma: English

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