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Premature myocardial infarction is strongly associated with increased levels of remnant cholesterol

Goliasch, Georg ; Wiesbauer, Franz ; Blessberger, Hermann ; Demyanets, Svitlana ; Wojta, Johann ; Huber, Kurt ; Maurer, Gerald ; Schillinger, Martin ; Speidl, Walter S

Journal of Clinical Lipidology, November 2015, Vol.9(6), pp.801-806.e1 [Periódico revisado por pares]

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  • Título:
    Premature myocardial infarction is strongly associated with increased levels of remnant cholesterol
  • Autor: Goliasch, Georg ; Wiesbauer, Franz ; Blessberger, Hermann ; Demyanets, Svitlana ; Wojta, Johann ; Huber, Kurt ; Maurer, Gerald ; Schillinger, Martin ; Speidl, Walter S
  • Assuntos: Remnant Cholesterol ; Lipids ; Premature Myocardial Infarction
  • É parte de: Journal of Clinical Lipidology, November 2015, Vol.9(6), pp.801-806.e1
  • Descrição: Remnant cholesterol has been defined as the cholesterol present in triglyceride-rich remnant lipoproteins. Elevated levels of remnant cholesterol have been associated with increased cardiovascular risk. Acute myocardial infarction (AMI) in very young individuals (≤40 years) represents a rare disease with a typical risk factor profile and a lipid phenotype that is characterized by a predominance of elevated triglyceride-rich lipoproteins. The aim of this study was to investigate the role of remnant cholesterol in premature AMI. We prospectively enrolled 302 patients into our multicenter case-control study comprising 102 consecutive myocardial infarction survivors (≤40 years) and 200 hospital controls. Myocardial infarction patients were frequency matched for age, gender, and center. Remnant cholesterol was calculated from standard lipid parameters. Remnant cholesterol was 1.7-fold higher in premature AMI patients compared...
  • Idioma: Inglês

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