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Impact of Intragastric Balloon Before Laparoscopic Gastric Bypass on Patients with Super Obesity: a Randomized Multicenter Study

Coffin, B ; Maunoury, V ; Pattou, F ; Hébuterne, X ; Schneider, S ; Coupaye, M ; Ledoux, S ; Iglicki, F ; Mion, F ; Robert, M ; Disse, E ; Escourrou, J ; Tuyeras, G ; Le Roux, Y ; Arvieux, C ; Pouderoux, P ; Huten, N ; Alfaiate, T ; Hajage, D ; Msika, S

Obesity surgery, April 2017, Vol.27(4), pp.902-909 [Periódico revisado por pares]

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  • Título:
    Impact of Intragastric Balloon Before Laparoscopic Gastric Bypass on Patients with Super Obesity: a Randomized Multicenter Study
  • Autor: Coffin, B ; Maunoury, V ; Pattou, F ; Hébuterne, X ; Schneider, S ; Coupaye, M ; Ledoux, S ; Iglicki, F ; Mion, F ; Robert, M ; Disse, E ; Escourrou, J ; Tuyeras, G ; Le Roux, Y ; Arvieux, C ; Pouderoux, P ; Huten, N ; Alfaiate, T ; Hajage, D ; Msika, S
  • Assuntos: Bridge Therapy ; Complications ; Gastric Balloon ; Gastric Bypass ; Morbid Obesity ; Gastric Balloon ; Gastric Bypass ; Obesity, Morbid -- Surgery
  • É parte de: Obesity surgery, April 2017, Vol.27(4), pp.902-909
  • Descrição: Super obese patients are recommended to lose weight before bariatric surgery. The effect of intragastric balloon (IGB)-induced weight loss before laparoscopic gastric bypass (LGBP) has not been reported. The aim of this prospective randomized multicenter study was to compare the impact of preoperative 6-month IGB with standard medical care (SMC) in LGBP patients. Patients with BMI >45 kg/m selected for LGBP were included and randomized to receive either SMC or IGB. After 6 months (M6), the IGB was removed and LGBP was performed in both groups. Postoperative follow-up period was 6 months (M12). The primary endpoint was the proportion of patients requiring ICU stay >24 h; secondary criteria were weight changes, operative time, hospitalization stay, and perioperative complications. Only 115 patients were included (BMI 54.3 ± 8.7 kg/m), of which 55 underwent IGB insertion. The proportion of patients who stayed in ICU >24 h was similar in both groups (P = 0.87). At M6, weight loss was significantly greater in the IGB group than in the SMC group (P < 0.0001). Three severe complications occurred during IGB removal. Mean operative time for LGBP was similar in both groups (P = 0.49). Five patients had 1 or more surgical complications, all in the IGB group (P = 0.02). Both groups had similar hospitalization stay (P = 0.59) and weight loss at M12 (P = 0.31). IGB insertion before LGBP induced weight loss but did not improve the perioperative outcomes or affect postoperative weight loss.
  • Idioma: Inglês

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