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Health versus disease as the catalyst for biomedical research: the science of adipokines as a case in point

Fantuzzi, Giamila

Frontiers in endocrinology, 2014, Vol.5, pp.136 [Periódico revisado por pares]

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  • Título:
    Health versus disease as the catalyst for biomedical research: the science of adipokines as a case in point
  • Autor: Fantuzzi, Giamila
  • Assuntos: 20th Century ; Adipokines ; Adiponectin ; History ; Leptin ; Pathology ; Physiology
  • É parte de: Frontiers in endocrinology, 2014, Vol.5, pp.136
  • Descrição: A common piece of advice when mentoring biomedical researchers preparing their first grant proposals is to focus on a specific disease or narrow range of conditions. The assumption is that proposing to investigate the pathological aspects of a problem – to study deviation from homeostasis – makes for a stronger project than approaching research through the lens of physiology, the study of the homeostatic state. Using the discovery of the adipokines leptin and adiponectin as an example, I question this assumption and discuss how both approaches can generate excellent research.
  • Idioma: Inglês

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