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Rice consumption contributes to arsenic exposure in US women

Gilbert-Diamond, Diane ; Cottingham, Kathryn L ; Gruber, Joann F ; Punshon, Tracy ; Sayarath, Vicki ; Gandolfi, A Jay ; Baker, Emily R ; Jackson, Brian P ; Folt, Carol L ; Karagas, Margaret R

Proceedings of the National Academy of Sciences of the United States of America, 20 December 2011, Vol.108(51), pp.20656-60 [Periódico revisado por pares]

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  • Título:
    Rice consumption contributes to arsenic exposure in US women
  • Autor: Gilbert-Diamond, Diane ; Cottingham, Kathryn L ; Gruber, Joann F ; Punshon, Tracy ; Sayarath, Vicki ; Gandolfi, A Jay ; Baker, Emily R ; Jackson, Brian P ; Folt, Carol L ; Karagas, Margaret R
  • Assuntos: Oryza ; Arsenic -- Toxicity
  • É parte de: Proceedings of the National Academy of Sciences of the United States of America, 20 December 2011, Vol.108(51), pp.20656-60
  • Descrição: Emerging data indicate that rice consumption may lead to potentially harmful arsenic exposure. However, few human data are available, and virtually none exist for vulnerable periods such as pregnancy. Here we document a positive association between rice consumption and urinary arsenic excretion, a biomarker of recent arsenic exposure, in 229 pregnant women. At a 6-mo prenatal visit, we collected a urine sample and 3-d dietary record for water, fish/seafood, and rice. We also tested women's home tap water for arsenic, which we combined with tap water consumption to estimate arsenic exposure through water. Women who reported rice intake (n = 73) consumed a median of 28.3 g/d, which is ∼0.5 cup of cooked rice each day. In general linear models adjusted for age and urinary dilution, both rice consumption (g, dry mass/d) and arsenic exposure through water (μg/d) were significantly associated with natural log-transformed total urinary arsenic (βrice = 0.009, βwater = 0.028, both P < 0.0001),...
  • Idioma: Inglês

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