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Mechanical properties and in vitro bioactivity of Ca5(PO4)2SiO4 bioceramic

Lu, Wenhao ; Duan, Wei ; Guo, Yaping ; Ning, Congqin

Journal of biomaterials applications, February 2012, Vol.26(6), pp.637-50 [Periódico revisado por pares]

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  • Título:
    Mechanical properties and in vitro bioactivity of Ca5(PO4)2SiO4 bioceramic
  • Autor: Lu, Wenhao ; Duan, Wei ; Guo, Yaping ; Ning, Congqin
  • Assuntos: Apatites -- Metabolism ; Biocompatible Materials -- Metabolism ; Calcium Phosphates -- Metabolism ; Ceramics -- Metabolism ; Durapatite -- Metabolism ; Silicates -- Metabolism
  • É parte de: Journal of biomaterials applications, February 2012, Vol.26(6), pp.637-50
  • Descrição: Pure Ca(5)(PO(4))(2)SiO(4) bioceramic was first prepared by a sol-gel method using triethyl phosphate, tetraethoxysilane, and calcium nitrate tetrahydrate as original materials. Simulated body fluid (SBF) immersion tests revealed that Ca(5)(PO(4))(2)SiO(4) samples had a greater in vitro apatite-forming ability than hydroxyapatite (HA). After soaking Ca(5)(PO(4))(2)SiO(4) samples in the SBF for 1 day, bone-like apatite precipitated on the surfaces and the apatite layer became thicker with increasing the soaking time. However, few bone-like apatites precipitated on the HA samples even after soaking in the SBF for 7 days. The good in vitro bioactivity of Ca(5)(PO(4))(2)SiO(4) samples was attributed to the silanol (Si-OH) groups and greater solubility of Ca(5)(PO(4))(2)SiO(4). In addition, hot-pressed Ca(5)(PO(4))(2)SiO(4) ceramic exhibited lower bending strength and elastic modulus than hot-pressed HA, since the former had a lower relative density than the latter. The results have shown that...
  • Idioma: Inglês

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