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Changes in glomerular structure following acute mesangial failure in the isolated perfused kidney

Sakai, T ; Lemley, K V ; Hackenthal, E ; Nagata, M ; Nobiling, R ; Kriz, W

Kidney international, March 1992, Vol.41(3), pp.533-41 [Periódico revisado por pares]

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  • Título:
    Changes in glomerular structure following acute mesangial failure in the isolated perfused kidney
  • Autor: Sakai, T ; Lemley, K V ; Hackenthal, E ; Nagata, M ; Nobiling, R ; Kriz, W
  • Assuntos: Acute Kidney Injury -- Pathology ; Kidney Glomerulus -- Pathology
  • É parte de: Kidney international, March 1992, Vol.41(3), pp.533-41
  • Descrição: The glomerular tuft is a complex network of tortuous anastomosing capillaries supported by an axial mesangial stalk and invested with a tough basement membrane "sack," which is itself surrounded by a layer of visceral epithelial cells. Under normal conditions, the complex architecture of the capillary tuft is maintained despite a high transmural hydrostatic pressure gradient which should favor capillary expansion. Some of the mechanical details of the way in which mesangium and GBM function as an integrated unit to resist capillary expansion have recently been examined [1–3].
  • Idioma: Inglês

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