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Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and Prediction

Mayrink, J ; Costa, M. L ; Cecatti, J. G Tamargo, Juan

The Scientific World Journal, 2018, Vol.2018, 9 pages [Periódico revisado por pares]

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  • Título:
    Preeclampsia in 2018: Revisiting Concepts, Physiopathology, and Prediction
  • Autor: Mayrink, J ; Costa, M. L ; Cecatti, J. G
  • Tamargo, Juan
  • Assuntos: Review Article
  • É parte de: The Scientific World Journal, 2018, Vol.2018, 9 pages
  • Descrição: Preeclampsia currently remains one of the leading causes of death and severe maternal morbidity. Although its prevalence is still underestimated in some places due to underreporting, preeclampsia is a disease that health professionals need to know how to deal with and take action. For this reason, the studies about the theme remain along with the advances in their understanding that often implies improvement and change of concepts and conducts. The complexity of its etiology is a challenge and requires further studies for its full understanding. Apparently, poor adaptation of the maternal organism to the conceptus, marked by the nonoccurrence of changes in the uterine spiral arteries, determines a series of systemic repercussions that compound the various forms of preeclampsia presentation. In recent years, the use of acetylsalicylic acid to prevent cases of early onset of the disease has been consolidated and, alongside, studies have advanced the development of accessible and effective methods of identifying women at risk of preeclampsia. The aim of this review is to discuss updates on the occurrence, concept, pathophysiology, repercussion, prevention, and prediction of preeclampsia.

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