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Risks associated with vaccinia virus in the laboratory

Macneil, Adam ; Reynolds, Mary G. ; Damon, Inger K.

Virology, March 1, 2009, Vol.385(1), p.1(4) [Periódico revisado por pares]

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  • Título:
    Risks associated with vaccinia virus in the laboratory
  • Autor: Macneil, Adam ; Reynolds, Mary G. ; Damon, Inger K.
  • Assuntos: Smallpox Vaccines -- Complications And Side Effects ; Smallpox -- Complications And Side Effects ; Vaccinia -- Complications And Side Effects ; Vaccination
  • É parte de: Virology, March 1, 2009, Vol.385(1), p.1(4)
  • Descrição: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.virol.2008.11.045 Byline: Adam MacNeil, Mary G. Reynolds, Inger K. Damon Keywords: Vaccinia; Laboratory-acquired infection; Orthopoxvirus; Vaccination; Smallpox vaccine Abstract: Vaccinia virus (VACV) is used commonly in research laboratories. Non-highly attenuated strains of VACV are potentially pathogenic in humans, and VACV vaccination and biosafety level 2 facilities and protocols are currently recommended for vaccinated laboratory workers in the United States who handle non-highly attenuated strains of the virus. Despite this, laboratory-related VACV exposures continue to occur and a number of recent instances of VACV infection in non-vaccinated laboratory workers have been documented. We provide a discussion of the usage and risks associated with VACV in laboratory research. Author Affiliation: Poxvirus and Rabies Branch, Division of Viral and Rickettsial Diseases, National Center for Zoonotic, Vector-Borne, and Enteric Diseases, Centers for Disease Control and Prevention, Atlanta, GA, USA Article History: Received 22 September 2008; Revised 23 November 2008; Accepted 26 November 2008 Article Note: (footnote) [star] The findings and conclusions in this report are those of the authors and do not necessarily represent the views of the Centers for Disease Control and Prevention.
  • Idioma: English

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