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FV 9. Diffusion Tensor Imaging in Neuromuscular diseases - A novel method for quantification of muscle degeneration in myopathy patients

Rehmann, R ; Schlaffke, L ; Vorgerd, M ; Tegenthoff, M ; Schmidt-Wilcke, T

Clinical Neurophysiology, September 2016, Vol.127(9), pp.e214-e215 [Periódico revisado por pares]

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  • Título:
    FV 9. Diffusion Tensor Imaging in Neuromuscular diseases - A novel method for quantification of muscle degeneration in myopathy patients
  • Autor: Rehmann, R ; Schlaffke, L ; Vorgerd, M ; Tegenthoff, M ; Schmidt-Wilcke, T
  • Assuntos: Medicine
  • É parte de: Clinical Neurophysiology, September 2016, Vol.127(9), pp.e214-e215
  • Descrição: To link to full-text access for this article, visit this link: http://dx.doi.org/10.1016/j.clinph.2016.05.026 Byline: R. Rehmann, L. Schlaffke, M. Vorgerd, M. Tegenthoff, T. Schmidt-Wilcke Abstract: The field of rare Myopathy diseases lacks in non-invasive, however quantifiable methods for evaluating states of diseases as well as monitoring disease progress and therapies. Therefore Diffusion Tensor Imaging (DTI) for non-invasive indirect representation of muscle fibre structure of human skeletal muscles, is a very promising tool for investigating and quantifying disease dependent structural changes, which cannot be observed using conventional imaging methods. DTI provides indirect measures of diffusion quantity and microstructure properties of skeletal muscles by fractional anisotropy (FA) and mean diffusivity (MD). Although there is raising evidence of this method in healthy control groups, little is known about disease dependent changes in diffusion properties.
  • Idioma: Inglês

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