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Bridging therapy after recent stent implantation: case report and review of data

Wessler, Jeffrey D ; Saldana, Fidencio ; Giugliano, Robert P

Cardiovascular Revascularization Medicine, 2012, Vol.13(1), pp.30-38 [Periódico revisado por pares]

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  • Título:
    Bridging therapy after recent stent implantation: case report and review of data
  • Autor: Wessler, Jeffrey D ; Saldana, Fidencio ; Giugliano, Robert P
  • Assuntos: Bridge Therapy ; Coronary Stents ; Antiplatelet Therapy ; Glycoprotein (GP) Iib/Iiia Inhibitor ; Medicine
  • É parte de: Cardiovascular Revascularization Medicine, 2012, Vol.13(1), pp.30-38
  • Descrição: For patients requiring surgery within their first year following coronary stent placement, maximizing the prevention of stent thrombosis with antiplatelet therapy while minimizing the risk of intraoperative bleeding has become a management challenge for cardiologists, surgeons and anesthesiologists. In this manuscript, we describe a case of a patient who received three stents (two of which were drug-eluting) and 7 months later was bridged with intravenous eptifibatide, a short-acting glycoprotein (GP) IIb/IIIa inhibitor, for 3 days prior to bronchoscopy and cervical mediastinoscopy for a suspected lung cancer. We then review the current literature for data and guidelines describing the use of short-acting GP IIb/IIIa as bridge therapy. Finally, we provide recommendations, based on our experience combined with this review, for bridge therapy in the perioperative period for patients with recent coronary stents.
  • Idioma: Inglês

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