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A critical evaluation of the planning target volume for 3-D conformal radiotherapy of prostate cancer

Tinger, Alfred ; Michalski, Jeff M ; Cheng, Abel ; Low, Daniel A ; Zhu, Ron ; Bosch, Walter R ; Purdy, James A ; Perez, Carlos A

International Journal of Radiation Oncology, Biology, Physics, 1998, Vol.42(1), pp.213-221 [Periódico revisado por pares]

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  • Título:
    A critical evaluation of the planning target volume for 3-D conformal radiotherapy of prostate cancer
  • Autor: Tinger, Alfred ; Michalski, Jeff M ; Cheng, Abel ; Low, Daniel A ; Zhu, Ron ; Bosch, Walter R ; Purdy, James A ; Perez, Carlos A
  • Assuntos: Radiotherapy ; 3d Conformal ; Prostate Cancer ; Uncertainty ; Organ Motion ; Treatment Planning ; Radiotherapy ; 3d Conformal ; Prostate Cancer ; Uncertainty ; Organ Motion ; Treatment Planning ; Medicine
  • É parte de: International Journal of Radiation Oncology, Biology, Physics, 1998, Vol.42(1), pp.213-221
  • Descrição: Purpose: To determine an adequate planning target volume (PTV) margin for three-dimensional conformal radiotherapy (3D CRT) of prostate cancer, the uncertainties in the internal positions of the prostate and seminal vesicles (SV) and in the treatment setups were measured. Methods and Materials: Weekly computed tomography (CT) scans of the pelvis ( n = 51) and daily electronic portal images ( n = 1630) were reviewed for eight patients who received seven-field 3D CRT for prostate cancer. The CT scans were registered in three dimensions to the original planning CT scan using commercially available software to measure the center-of volume (COV) motion of the prostate and SV. The daily portal images were registered to the corresponding simulation films to measure the setup displacements. The standard deviation (SD) of the internal organ motions was added to the SD of the setups in quadrature to determine the total uncertainty. Positive directions were left,...
  • Idioma: Inglês

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