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Dynamic changes of resting state connectivity related to the acquisition of a lexico-semantic skill

Schlaffke, L ; Schweizer, L ; Rüther, N.N ; Luerding, R ; Tegenthoff, M ; Bellebaum, C ; Schmidt-Wilcke, T

NeuroImage, 01 February 2017, Vol.146, pp.429-437 [Periódico revisado por pares]

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  • Título:
    Dynamic changes of resting state connectivity related to the acquisition of a lexico-semantic skill
  • Autor: Schlaffke, L ; Schweizer, L ; Rüther, N.N ; Luerding, R ; Tegenthoff, M ; Bellebaum, C ; Schmidt-Wilcke, T
  • Assuntos: Resting State – Fmri ; Resting State Connectivity ; Learning ; Neuroplasticity ; Language ; Asn ; BA ; Bold ; Dmn ; Fnc ; Fdr ; Fmri ; Fwe ; Ica ; Ifc ; IFC ; Ipl ; Lang ; MC
  • É parte de: NeuroImage, 01 February 2017, Vol.146, pp.429-437
  • Descrição: The brain undergoes adaptive changes during learning. Spontaneous neural activity has been proposed to play an important role in acquiring new information and/or improve the interaction of task related brain regions. A promising approach is the investigation of resting state functional connectivity (rs-fc) and resting state networks, which rely on the detection of interregional correlations of spontaneous BOLD fluctuations. Using Morse Code (MC) as a model to investigate neural correlates of lexico-semantic learning we sought to identify patterns in rs-fc that predict learning success and/or undergo dynamic changes during a 10-day training period. Thirty-five participants were trained to decode twelve letters of MC. Rs-fMRI data were collected before and after the training period and rs-fc analyses were performed using a group independent component analysis. Baseline connectivity between the language-network (LANG) and the anterior-salience-network...
  • Idioma: Inglês

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