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Contact allergy to fragrance mix I and its components in individuals with photocontact allergy to ketoprofen

Marmgren, Victoria ; Mowitz, Martin ; Zimerson, Erik ; Hindsén, Monica ; Bruze, Magnus

Contact dermatitis, 2021-12, Vol.85 (6), p.660-670 [Periódico revisado por pares]

Oxford, UK: Blackwell Publishing Ltd

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Título:
Contact allergy to fragrance mix I and its components in individuals with photocontact allergy to ketoprofen
Autor: Marmgren, Victoria ; Mowitz, Martin ; Zimerson, Erik ; Hindsén, Monica ; Bruze, Magnus
Assuntos: Acrolein - adverse effects ; Acrolein - analogs & derivatives ; Adolescent ; Adult ; Aged ; Aged, 80 and over ; Anti-Inflammatory Agents, Non-Steroidal - adverse effects ; chemical analysis ; Child ; Child, Preschool ; cinnamal ; cinnamyl alcohol ; Clinical Medicine ; contamination ; delayed hypersensitivity ; Dermatitis ; Dermatitis, Photoallergic - epidemiology ; Dermatitis, Photoallergic - etiology ; Dermatologi och venereologi ; Dermatology and Venereal Diseases ; Eugenol ; Female ; fragrance substance ; GC–MS ; Humans ; Hypersensitivity ; Isoeugenol ; Ketoprofen ; Ketoprofen - adverse effects ; Klinisk medicin ; Male ; Medical and Health Sciences ; Medicin och hälsovetenskap ; Middle Aged ; NSAID ; patch testing ; Perfume - adverse effects ; photopatch testing ; Propanols - adverse effects ; Retrospective Studies ; Young Adult
É parte de: Contact dermatitis, 2021-12, Vol.85 (6), p.660-670
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
content type line 23
Descrição: Background Contact allergy to fragrance mix I (FM I) is over‐represented in patients photoallergic to ketoprofen. The prevalence of contact allergy to two components of FM I, cinnamal and cinnamyl alcohol, in ketoprofen‐photoallergic patients is higher than in dermatitis patients. Objective To explore the prevalence of contact allergy to FM I and its individual components in patients with photocontact allergy to ketoprofen, and to compare with a dermatitis and the general population. Methods Data on patch and photopatch tests performed between 2009‐2018 were collected. Ketoprofen‐photoallergic patients were compared with dermatitis patients and published data on the general population regarding the prevalence and the distribution of contact allergy to FM I and its components. Results A higher prevalence of contact allergy to cinnamyl alcohol compared with cinnamal (23.3% vs 10.0%), and eugenol compared with isoeugenol (23.3% vs 6.7%), was observed in ketoprofen‐photoallergic patients, while the relationship was the opposite in the dermatitis group (0.7% vs 1.05%; 0.4% vs 0.9%). The overall prevalence of contact allergy to several components of FM I was significantly higher in ketoprofen‐photoallergic patients. Conclusions Contact allergy to FM I and many of its components is over‐represented in patients photoallergic to ketoprofen compared with dermatitis patients and the general population.
Editor: Oxford, UK: Blackwell Publishing Ltd
Idioma: Inglês

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Contact allergy to fragrance mix I and its components in individuals with photocontact allergy to ketoprofen

Marmgren, Victoria ; Mowitz, Martin ; Zimerson, Erik ; Hindsén, Monica ; Bruze, Magnus

Oxford, UK: Blackwell Publishing Ltd

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