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Laser-wakefield accelerators as hard x-ray sources for 3D medical imaging of human bone

Cole, J M ; Wood, J C ; Lopes, N C ; Poder, K ; Abel, R L ; Alatabi, S ; Bryant, J S J ; Jin, A ; Kneip, S ; Mecseki, K ; Symes, D R ; Mangles, S P D ; Najmudin, Z

Scientific reports, 2015-08, Vol.5 (1), p.13244-13244, Article 13244 [Periódico revisado por pares]

England: Nature Publishing Group

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Título:
Laser-wakefield accelerators as hard x-ray sources for 3D medical imaging of human bone
Autor: Cole, J M ; Wood, J C ; Lopes, N C ; Poder, K ; Abel, R L ; Alatabi, S ; Bryant, J S J ; Jin, A ; Kneip, S ; Mecseki, K ; Symes, D R ; Mangles, S P D ; Najmudin, Z
Assuntos: Absorptiometry, Photon - instrumentation ; Bone (trabecular) ; Bone imaging ; Brightness ; Computed tomography ; Equipment Design ; Equipment Failure Analysis ; Femur ; Femur - diagnostic imaging ; Humans ; Image Enhancement - instrumentation ; Imaging, Three-Dimensional - instrumentation ; In Vitro Techniques ; Lasers ; Medical imaging ; Oscillations ; Particle Accelerators - instrumentation ; Reproducibility of Results ; Sensitivity and Specificity ; Tomography, X-Ray Computed - instrumentation ; X-rays
É parte de: Scientific reports, 2015-08, Vol.5 (1), p.13244-13244, Article 13244
Notas: ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
Descrição: A bright μm-sized source of hard synchrotron x-rays (critical energy Ecrit > 30 keV) based on the betatron oscillations of laser wakefield accelerated electrons has been developed. The potential of this source for medical imaging was demonstrated by performing micro-computed tomography of a human femoral trabecular bone sample, allowing full 3D reconstruction to a resolution below 50 μm. The use of a 1 cm long wakefield accelerator means that the length of the beamline (excluding the laser) is dominated by the x-ray imaging distances rather than the electron acceleration distances. The source possesses high peak brightness, which allows each image to be recorded with a single exposure and reduces the time required for a full tomographic scan. These properties make this an interesting laboratory source for many tomographic imaging applications.
Editor: England: Nature Publishing Group
Idioma: Inglês

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Laser-wakefield accelerators as hard x-ray sources for 3D medical imaging of human bone

Cole, J M ; Wood, J C ; Lopes, N C ; Poder, K ; Abel, R L ; Alatabi, S ; Bryant, J S J ; Jin, A ; Kneip, S ; Mecseki, K ; Symes, D R ; Mangles, S P D ; Najmudin, Z

England: Nature Publishing Group

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