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Antibiotic Usage and Resistance: Gaining or Losing Ground on Infections in Critically Ill Patients?

Opal, Steven M ; Calandra, Thierry

JAMA : the journal of the American Medical Association, 2009-12, Vol.302 (21), p.2367-2368 [Periódico revisado por pares]

United States: American Medical Association

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Título:
Antibiotic Usage and Resistance: Gaining or Losing Ground on Infections in Critically Ill Patients?
Autor: Opal, Steven M ; Calandra, Thierry
Assuntos: Anti-Bacterial Agents - therapeutic use ; Antibiotics ; Cost of Illness ; Critical Illness ; Drug resistance ; Drug Resistance, Bacterial ; Drug therapy ; Drug Utilization ; Global Health ; Humans ; Infection - drug therapy ; Infection - epidemiology ; Infections ; Intensive care ; Intensive Care Units - statistics & numerical data ; Patients
É parte de: JAMA : the journal of the American Medical Association, 2009-12, Vol.302 (21), p.2367-2368
Notas: SourceType-Other Sources-1
content type line 63
ObjectType-Editorial-2
ObjectType-Commentary-1
Descrição: The increasing prevalence of antibiotic resistance genes among bacteria in the community and the continued exposure of commensal bacteria to antibiotics ensures that antibiotic resistance will persist and likely worsen in the future. While contamination from the environment and cross-infection from the hands and devices of health care workers account for some infections, many infections are caused by the intrinsic microorganisms residing within or on the patient at the time of arrival in the ICU. Critically ill patients regularly exposed to invasive procedures will continue to experience morbidity from bacterial and fungal infections. Without some radical new intervention, trends in antibiotic resistance will continue to emerge, and therapeutic options will become increasingly limited. Here, Opal and Calandra discuss the emerging antibiotic resistance and look at what the future holds for antimicrobial therapy.
Editor: United States: American Medical Association
Idioma: Inglês

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Antibiotic Usage and Resistance: Gaining or Losing Ground on Infections in Critically Ill Patients?

Opal, Steven M ; Calandra, Thierry

United States: American Medical Association

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