skip to main content
Idioma:
Primo Search
Clear Search Box
Search in: Busca Geral
Busca Avançada
Busca por Índices

Genotype-environment interaction on arterial stiffness: A pedigree-based study

Wang, X H ; Wang, S Y ; Peng, H X ; Fan, M ; Guo, H D ; Hou, T J ; Wang, M Y ; Wu, Y Q ; Qin, X Y ; Tang, X ; Li, J ; Chen, D F ; Hu, Y H ; Wu, T

Beijing da xue xue bao. Journal of Peking University. Yi xue ban, 2023-06, Vol.55 (3), p.400-407 [Periódico revisado por pares]

China

Texto completo disponível

Citações Citado por
  • Título:
    Genotype-environment interaction on arterial stiffness: A pedigree-based study
  • Autor: Wang, X H ; Wang, S Y ; Peng, H X ; Fan, M ; Guo, H D ; Hou, T J ; Wang, M Y ; Wu, Y Q ; Qin, X Y ; Tang, X ; Li, J ; Chen, D F ; Hu, Y H ; Wu, T
  • Assuntos: Ankle Brachial Index ; Cohort Studies ; Female ; Gene-Environment Interaction ; Genotype ; Humans ; Male ; Middle Aged ; Pedigree ; Pulse Wave Analysis - methods ; Vascular Stiffness - genetics
  • É parte de: Beijing da xue xue bao. Journal of Peking University. Yi xue ban, 2023-06, Vol.55 (3), p.400-407
  • Notas: ObjectType-Article-1
    SourceType-Scholarly Journals-1
    ObjectType-Feature-2
    content type line 23
  • Descrição: To utilized the baseline data of the Beijing Fangshan Family Cohort Study, and to estimate whether the association between a healthy lifestyle and arterial stiffness might be modified by genetic effects. Probands and their relatives from 9 rural areas in Fangshan district, Beijing were included in this study. We developed a healthy lifestyle score based on five lifestyle behaviors: smoking, alcohol consumption, body mass index (BMI), dietary pattern, and physical activity. The measurements of arterial stiffness were brachial-ankle pulse wave velocity (baPWV) and ankle-brachial index (ABI). A variance component model was used to determine the heritability of arterial stiffness. Genotype-environment interaction effects were performed by the maximum likelihood methods. Subsequently, 45 candidate single nucleotide polymorphisms (SNPs) located in the glycolipid metabolism pathway were selected, and generalized estimated equations were used to assess the gene-environment interaction effects between particular genet
  • Editor: China
  • Idioma: Chinês
Links
Voltar para lista de resultados
Resultado  1 AvançarIr para próxima página

  • Realização: ABCD-USP USP   Logos de Redes Sociais: Freepik

Buscando em bases de dados remotas. Favor aguardar.